journal
https://read.qxmd.com/read/38775587/erratum
#1
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[This corrects the article doi: 10.1590/S0004-2803.24612023-117].
May 20, 2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38775586/correlation-of-leptin-and-adiponectin-receptor-expression-with-clinicopathological-parameters-in-colorectal-carcinoma-a-cross-sectional-prospective-study
#2
JOURNAL ARTICLE
Priyanka Parmesh, Udupi Shastri Dinesh, Ajay S Khandagale, Anil Bargale Bapu, Roshni Sadashiv, Pradnya Reddy
BACKGROUND: Colorectal carcinoma (CRC) is one of the common carcinomas with a rising incidence of metastasis due to its advanced stage of presentation. The existing biomarkers such as CEA (Carcinoembryonic antigen) etc., for prognosis, have low sensitivity and specificity. Hence a need for a newer definitive biomarker. Obesity is the leading cause of CRC. Leptin and adiponectin secreted by adipose tissue have been studied as potential biomarkers in the field of CRC. The present study helps to understand the association of leptin and adiponectin receptors with clinicopathological parameters...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38775585/spontaneous-regression-of-hepatocellular-carcinoma-focusing-in-the-associated-risk-factors
#3
JOURNAL ARTICLE
Cristiane Valle Tovo, Carolina Rossatto Ribas, Giovana Dal Pozzo Sartori, Gabriela Perdomo Coral, Eiji Suwa, Angelo Alves de Mattos
BACKGROUND: Spontaneous regression (SR) is defined as the partial or complete disappearance of a tumor, in the absence of a specific treatment. Evidence of the SR in hepatocellular carcinoma (HCC) is rare. OBJECTIVE: The authors aimed to review all the cases of SR of HCC in two reference centers of Southern Brazil, highlighting the main characteristics. METHODS: Data of all patients with HCC were retrospectively reviewed looking for the occurrence of SR in patients from two tertiary centers in Southern Brazil, in the last five years...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38775584/adherence-and-persistence-to-treatment-with-infliximab-analysis-of-a-patient-support-program-cohort-in-brazil
#4
JOURNAL ARTICLE
Aniela Bonorino Xexeo Castelo Branco, Wilton Argolo, Nathalia Santos, Gabriela Hernandez, Adriana Kakehasi, Carlos Walter Sobrado, Richard Melsheimer
BACKGROUND: Monoclonal antibodies have proven efficacy in the management of several conditions and infliximab (IFX) is one of the most important drugs of the class. Some recent data have shown low rates of both persistence and adherence to several available biologics. OBJECTIVE: The objective of this study was to describe adherence and persistence rate to IFX treatment and also persistence in the patient support program (PSP), among patients diagnosed with inflammatory bowel diseases (IBD) or rheumatic diseases (RD) enrolled in the program of a large pharmaceutical company in Brazil...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38775583/clinical-characteristics-and-outcomes-of-patients-with-severe-covid-19-and-cirrhosis-or-liver-transplant-in-a-brazilian-quaternary-center
#5
JOURNAL ARTICLE
Tulio L Correa, Mariana Sandoval Terra Campos Guelli, Ricardo Tavares de Carvalho
BACKGROUND: Specific associations between liver cirrhosis and liver transplant with poorer outcomes in COVID-19 are still not completely clear. OBJECTIVE: We aimed to evaluate the clinical characteristics and outcomes of patients with severe COVID-19 and cirrhosis or liver transplant in Sao Paulo, Brazil. METHODS: A retrospective observational study was conducted in a quaternary hospital. Patients with COVID-19 and liver cirrhosis or liver transplant were selected...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38775582/decreased-expression-of-microrna-629-in-gastric-cancer-samples-potentiated-by-the-virulence-marker-of-h-pylori-caga-gene
#6
JOURNAL ARTICLE
Caroline Dos Reis Rodrigues Soares, Lucas Matheus Vieira da Silva, Bianca Reis Almeida, Jéssica Nunes Pereira, Mônica Pezenatto Dos Santos, Mônica Santiago Barbosa, Marília de Arruda Cardoso Smith, Spencer Luiz Marques Payão, Lucas Trevizani Rasmussen
BACKGROUND: Helicobacter pylori (H. pylori) is a gram-negative bacterium associated with the etiology of several gastrointestinal tract pathologies, and cagA-positive (cagA+) strains are found in populations with gastric ulcers and precancerous lesions, inducing pro-inflammatory responses. The development of neoplasms is related to microRNA (miRNA) dysregulation, indicating highly expressed miRNA-629. The article aims to correlate the expression level of miRNA-629 with the presence of H...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38511798/structural-evaluation-of-inflammatory-bowel-disease-comprehensive-care-units-in-brazil
#7
JOURNAL ARTICLE
Abel Botelho Quaresma, Ludmila Resende Guedes, Jaqueline Ribeiro de Barros, Júlio Pinheiro Baima, Marcello Imbrizi, Marco Antônio Zerôncio, Paulo Gustavo Kotze, Cristina Flores
BACKGROUND: The most efficient way to prevent complications from inflammatory bowel disease (IBD) is to provide patients with optimized care. Nonetheless, in Brazil, there is no validated methodology for evaluating health services recognized as comprehensive care units (CCU), making it difficult to assess the quality of care provided. OBJECTIVE: To understand the current scenario, map the distribution of centers and identify strengths and weaknesses, considering local and regional characteristics...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38511797/brazilian-clinical-guideline-for-the-therapeutic-management-of-gastroesophageal-reflux-disease-brazilian-federation-of-gastroenterology-fbg
#8
REVIEW
Joaquim Prado P Moraes-Filho, Gerson Domingues, Decio Chinzon
BACKGROUND: Gastroesophageal Reflux Disease (GERD) is a prevalent condition in Brazil, affecting 12% to 20% of the urban population, with significant implications for patient quality of life and potential for complications. OBJECTIVE: This paper focuses on the recent update of the Brazilian guidelines for GERD, a necessary revision due to advancements in knowledge and practice since the last publication over a decade ago. The update pays particular attention to the role and safety of proton pump inhibitors (PPIs), acknowledging the growing concerns about their long-term use, adverse events, and overprescription...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38511796/rate-of-infection-tuberculosis-in-brazilians-ibd-private-patients-follow-up-15-years
#9
JOURNAL ARTICLE
Didia B Cury, Liana C B Cury, Ana C Micheletti, Rogério A Oliveira, José J S Gonçalves
BACKGROUND: Latent tuberculosis (LTB) is a condition where the patient is infected with Mycobacterium tuberculosis but does not develop active TB. There's a possibility of tuberculosis (TB) activation following the introduction of anti-TNFs. OBJECTIVE: To assess the risk of biological therapy inducing LTB during inflammatory bowel diseases (IBD) treatment over 15 years in a high-risk area in Brazil. METHODS: A retrospective study of an IBD patients' database was carried out in a private reference clinic in Brazil...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38511795/hot-versus-cold-snare-for-colorectal-polypectomies-sized-up-to-10mm-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
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JOURNAL ARTICLE
Paulo Ricardo Pavanatto Cavassola, Diogo Turiani Hourneaux de Moura, Bruno Salomão Hirsch, Davi Lucena Landim, Wanderley Marques Bernardo, Eduardo Guimarães Hourneaux de Moura
BACKGROUND: Colorectal cancer is the third most common cancer, and prevention relies on screening programs with resection complete resection of neoplastic lesions. OBJECTIVE: We aimed to evaluate the best snare polypectomy technique for colorectal lesions up to 10 mm, focusing on complete resection rate, and adverse events. METHODS: A comprehensive search using electronic databases was conducted to identify randomized controlled trials comparing hot versus cold snare resection for polyps sized up to 10 mm, and following PRISMA guidelines, a meta-analysis was performed...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38511794/beyond-traditional-tools-exploring-convolutional-neural-networks-as-innovative-prognostic-models-in-pancreatic-ductal-adenocarcinoma
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JOURNAL ARTICLE
H Shafeeq Ahmed
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and lethal form of cancer with limited prognostic accuracy using traditional factors. This has led to the exploration of innovative prognostic models, including convolutional neural networks (CNNs), in PDAC. CNNs, a type of artificial intelligence algorithm, have shown promise in various medical applications, including image analysis and pattern recognition. Their ability to extract complex features from medical images makes them suitable for improving prognostication in PDAC...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38511793/comparison-of-gut-microbiota-in-alcoholic-and-metabolic-dysfuncion-associated-steatotic-liver-disease-in-animal-models
#12
JOURNAL ARTICLE
Cássio Marques Perlin, Larisse Longo, Rutiane Ullmann Thoen, Carolina Uribe-Cruz, Mário Reis Álvares-DA-Silva
BACKGROUND: Alcoholic liver disease (ALD) and metabolic-dysfunction associated steatotic liver disease (MASLD) are common, and gut microbiota (GM) is involved with both. Here we compared GM composition in animal models of MASLD and ALD to assess whether there are specific patterns for each disease. METHODS: MASLD model- adult male Sprague Dawley rats, randomized into two groups: MASLD-control (n=10) fed a standard diet; MASLD-group (n=10) fed a high-fat-choline-deficient diet for 16 weeks...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38511792/videofluoroscopic-evaluation-of-the-impact-of-capsule-size-and-subject-s-age-and-gender-on-capsule-swallowing
#13
JOURNAL ARTICLE
Laís Flavia de Souza Gutierres, Marina Rodrigues Montaldi, Weslania Viviane Nascimento, Roberto Oliveira Dantas
BACKGROUND: People recurrently have difficulties swallowing solid medications, which can be associated with the size of the medication and the age and gender of individuals. OBJECTIVE: To evaluate the impact of capsule size and adults' age and gender on oral and pharyngeal capsule transit during capsule swallows. METHODS: Videofluoroscopy was used to measure capsule oral and pharyngeal transit during swallows in 49 healthy individuals (17 men and 32 women), with a mean age of 46 years (ranging from 23 to 88 years)...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38451674/evaluating-lactoferrin-and-calprotectin-as-markers-of-intestinal-inflammation-inchronic-pancreatitis
#14
JOURNAL ARTICLE
Claudia Teresa Carvente, Maria Lúcia Cardoso Gomes Ferraz, Carlos Fischer de Toledo
BACKGROUND: The treatment of chronic pancreatitis does not consistently solve intestinal abnormalities, and despite the implementation of various therapeutic measures, patients often continue to experience persistent diarrhea. Therefore, it is imperative to recognize that diarrhea may stem from factors beyond pancreatic insufficiency, and intestinal inflammation emerges as a potential contributing factor. OBJECTIVE: The aim of this study was to assess fecal lactoferrin and calprotectin levels as indicators of intestinal inflammation in patients with chronic pancreatitis experiencing persistent diarrhea...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38451673/the-brazilian-blue-march-campaign
#15
EDITORIAL
Marcelo Averbach, Hélio Moreira Junior, Herbeth José Toledo Silva, Francisco Sérgio Rangel de Paula Pessoa
No abstract text is available yet for this article.
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38451672/behind-the-proton-pump-inhibitor-prescription-an-international-survey-on-physician-practices-and-knowledge
#16
JOURNAL ARTICLE
Jean Félix Piñerúa-Gonsálvez, Rosanna Del Carmen Zambrano-Infantino, Julio César Albornoz-Sandoval, Pedro Waykin Tong-Morao, Mariangel Nohemy León-Hernández, Barbara Daniela Matheus-Alonso, Frank Suárez-López, Yormalis Flores, Santos Neomar Higuera, María Lourdes Ruiz-Rebollo, Mariseli Sulbaran
BACKGROUND: Proton pump inhibitors (PPIs) are widely prescribed worldwide, often resulting in their overuse. Consequently, it is essential to identify the likely causes of this overuse to facilitate their appropriate prescription. OBJECTIVE: This study aims to assess physician prescribing patterns, their knowledge of PPIs, and factors affecting their knowledge. METHODS: An online survey was conducted among Latin American and Spanish physicians, collecting the following data: professional information, patterns of PPI usage, familiarity with published evidence, and the management approach in three hypothetical case-scenarios...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38451671/endosonography-guided-rescue-procedures-after-failed-ercp-in-a-patient-with-pancreatic-ductal-adenocarcinoma
#17
JOURNAL ARTICLE
José Celso Ardengh, Anna Carolina Orsini-Arman, Bruna Haueisen-Figueiredo, Guilherme Camarotti de Oliveira-Canejo, Otávio Micelli-Neto
BACKGROUND: • The ERCP even when done by experienced professionals, fails in 10% of cases. BACKGROUND: • Until the development of the EUS-BD, PTBD had a role as a rescue therapy, despite a high rate of adverse events. BACKGROUND: • The EUS-BD is safe and has similar efficacy, when compared to PTBD and should be performed immediately after ERCP failure. BACKGROUND: • A doctor with skills in both methods (ERCP/EUS) is needed to determine the best EUS-guided therapeutic option...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38451670/hospitalization-use-of-biologics-and-surgery-rates-in-inflammatory-bowel-diseases-a-single-centre-comparative-analysis-between-public-and-private-healthcare-systems-in-a-tertiary-unit-from-latin-america
#18
JOURNAL ARTICLE
Patrícia Zacharias, Daniéla Oliveira Magro, Milena Perussolo, Fernanda da Silva Barbosa Baraúna, Paulo Gustavo Kotze
BACKGROUND: Inflammatory bowel diseases (IBD) have rising incidence and prevalence rates globally. In IBD, there are scarce stu-dies comparing differences between patients according to socioeconomic status. Our aim was to comparatively evaluate hospitalizations, use of biologics and rates of surgery in patients with IBD between public and private healthcare systems. METHODS: Single-center retrospective cohort study in patients with IBD from a tertiary referral unit from Latin America, between 2015 and 2021...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38451669/assessment-of-the-accuracy-of-the-rapid-test-for-the-diagnosis-of-helicobacter-pylori-in-patients-that-didn-t-undergo-previous-eradication-therapy-and-who-went-through-endoscopy
#19
JOURNAL ARTICLE
Gianluca Z Rovaris, João V Back, Maria Paula Ronchi-Colombo, Vitória S Rosa, Manoel C B Cardoso, Emilio C Berger
BACKGROUND: Helicobacter pylori infection is widely spread globally and is known to cause potentially serious diseases. Several diagnostic methods exist to identify and treat carriers of this bacterium. Serological tests for the diagnosis of infection are based on the detection of antibodies immunoglobulin G against H. pylori, a non-invasive, inexpensive, and easy-to-perform option. OBJECTIVE: This research aims to ascertain the accuracy of an immunochromatographic serological test to verify the feasibility of using this method in patients who have not undergone previous eradication therapy...
2024: Arquivos de Gastroenterologia
https://read.qxmd.com/read/38451668/a-medical-and-neuropsychiatric-management-survey-in-a-brazilian-cohort-of-patients-with-inflammatory-bowel-disease-ibd
#20
JOURNAL ARTICLE
Antônio Miguel Furtado Leitão, José Lopes Tabatinga Neto, Marcellus Henrique Loiola Ponte de Souza, Lúcia Libanez Bessa Campelo Braga, Francisco de Assis Aquino Gondim
BACKGROUND: Inflammatory bowel disease (IBD) can be accompanied by several neurological disorders. Since 2004, we started a Brazilian cohort to assess neuropsychiatric complications in IBD patients. Changes in therapeutic strategy and differences in the prevalence and relevance of neuropsychiatric disorders have been reported in the literature. We conducted a short patient-reported survey about the medical management of IBD (with a special focus on neuropsychiatric management) and its complications...
2024: Arquivos de Gastroenterologia
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