Miao Li, Zhaofeng Pan, Qi He, Jiacong Xiao, Baihao Chen, Fanchen Wang, Pan Kang, Haoran Luo, Jianliang Li, Jiaxu Zeng, Shaocong Li, Junzheng Yang, Haibin Wang, Chi Zhou
Iron overload is a prevalent pathological factor observed among elderly individuals and those with specific hematological disorders, and is frequently associated with an elevated incidence of osteoporosis. Although arctiin (ARC) has been shown to possess antioxidant properties and the ability to mitigate bone degeneration, its mechanism of action in the treatment of iron overload‑induced osteoporosis (IOOP) remains incompletely understood. To explore the potential molecular mechanisms underlying the effects of ARC, the MC3T3‑E1 cell osteoblast cell line was used...
November 2023: International Journal of Molecular Medicine