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Journals Saudi Journal of Gastroenterol...

Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association

https://read.qxmd.com/read/37721255/efficacy-of-early-biologic-therapy-versus-late-conventional-therapy-in-children-and-adolescents-with-crohn-s-disease-a-systematic-review-and-meta-analysis
#21
JOURNAL ARTICLE
Lei Zhang, Zhixiao Jin, Jia Hao
BACKGROUND: The objective of this study was to estimate the effectiveness of early biologics compared to conventional treatment in the management of Crohn's disease among pediatric and adolescent patients. METHODS: A comprehensive literature search was conducted in four electronic databases to identify relevant studies published from inception to 2023. The inclusion criteria comprised randomized controlled trials (RCTs) and cohort studies that reported on the efficacy and clinical outcomes of early biologic therapy compared to late/conventional therapy in children with Crohn's disease...
September 15, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37706422/unlocking-the-path-to-efficient-h-pylori-eradication-embracing-potassium-competitive-acid-blockers-p-cabs
#22
EDITORIAL
Thomas J Borody, John Ng, Sibasish Dolai
No abstract text is available yet for this article.
September 11, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37706420/clinical-and-laboratory-features-of-biliary-atresia-and-patterns-of-management-practices-saudi-national-study-2000-2018
#23
JOURNAL ARTICLE
Homoud Alhebbi, Mohammed El-Edreesi, Mohammed Abanemai, Omar Saadah, Maher Alhatlani, Hana Halabi, Razan Bader, Ahmed Al Sarkhy, Ahmed Aladsani, Sami Wali, Talal Alguofi, Nawaf Alkhathran, Amira NasserAllah, Muhammed Salman Bashir, Abdulrahman Al-Hussaini
BACKGROUND: We utilized the data from the Saudi national biliary atresia (BA) study (2000-2018) to describe the clinical, biochemical, imaging, and histopathological features of BA and the perioperative clinical practices among local pediatric gastroenterologists. METHODS: This is a retrospective, multicenter, nationwide study that included 10 tertiary care governmental hospitals including the four liver transplant (LT) centers in different regions across Saudi Arabia...
September 6, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37706419/disease-patterns-among-saudi-children-undergoing-colonoscopy-for-lower-gastrointestinal-bleeding-single-tertiary-care-center-experience
#24
JOURNAL ARTICLE
Sami Alrashidi, Tarig AlAmery, Abdullah Alshanbary, Eman Aljohani, Salman M Bashir, Bader Alsaleem, Ali Asery, Abdulrahman Al-Hussaini
BACKGROUND: : The yield of colonoscopy in cases presenting with lower gastrointestinal bleeding (LGIB) in previously published studies varies according to several factors, including endoscopic skills, histopathological experience, and pattern of colonic pathology in different countries. The local literature is limited to a single small 20-year-old study. Our objective was to provide updated data on the diagnostic yield of colonoscopy in Saudi children with LGIB in Saudi Arabia. METHODS: : This was a retrospective analysis of pediatric patients (0-14 years of age) who underwent colonoscopy for LGIB at the King Fahad Medical City (KFMC), from 2008 to 2018...
September 6, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37635621/correlation-between-physician-and-patient-directed-disease-assessments-in-ulcerative-colitis-patients-from-saudi-arabia-and-kuwait-data-from-iconic
#25
JOURNAL ARTICLE
Othman Al Harbi, Salem Owayed, Yousif Qari, Mahmoud Mosli, Ali Anwar, Alaa Masri, Mohamed Gouda, Ahmed Alfadhli
BACKGROUND: The aim of the observational, prospective study was to validate a novel, nonverbal assessment tool for perceived disease burden-Pictorial Representation of Illness and Self-Measure (PRISM)-in ulcerative colitis (UC) against established patient health questionnaires. The cumulative burden of patients recently diagnosed (<3 years) with UC was also evaluated. METHODS: "ICONIC" - Understanding the impact of ulcerative colitis and its associated disease burden on patients - was a noninterventional, multicountry, multicenter study performed in a 2-year follow-up format in adult patients with recently diagnosed UC in 33 countries, regardless of disease severity or treatment...
August 23, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37602639/the-when-why-and-whom-to-biopsy-of-type-1-diabetes-mellitus-children-with-positive-anti-tissue-transglutaminase-serology
#26
EDITORIAL
Stefano Guandalini
No abstract text is available yet for this article.
August 9, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37602638/comparison-of-kras-gene-in-circulating-tumor-dna-levels-vs-histological-grading-of-colorectal-cancer-patients-through-liquid-biopsy
#27
JOURNAL ARTICLE
Hafiz Syed Mohammad Osama Jafri, Shamim Mushtaq, Saeeda Baig, Afreen Bhatty, Sabra Siraj
BACKGROUND: To determine KRAS gene in circulating tumor DNA in comparison with histological grading through liquid biopsy in colorectal cancer patients. METHODS: This dual-centered cross-sectional study included 73 diagnosed patients of colorectal cancer at different grading levels [Grade I, well differentiated (n = 7, 9.5%); Grade II, moderately differentiated (n = 14,18.9%); and Grade III, poorly differentiated (n = 52, 70%)]. Blood was collected, and plasma was separated...
August 8, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37602637/association-of-esophageal-motility-disorder-symptoms-with-chicago-classification-versions-3-0-and-4-0-using-high-resolution-esophageal-manometry-a-single-center-experience-from-saudi-arabia
#28
JOURNAL ARTICLE
Mohammed A Alzahrani, Mohammed A Alfahadi, Meshref A Alshehri, Abdulaziz H Alamri, Eman A Almahjani, Aishah M Alahmari, Abdullah A Al-Shahrani, Abdulaziz S Alshahrani, Ibrahim M Almanjahi, Abdullah M Alqarni
BACKGROUND: Esophageal motility disorders (EMDs) can significantly impact patients' quality of life. The Chicago Classification (CC) was developed as a robust framework to enable clinicians to better understand and classify the nature of motility disorders. Previous studies have primarily focused on the CC version 3.0 (CCv3.0), and data regarding the correlation between symptoms and CC version 4.0 (CCv4.0) in the Saudi Arabian population are lacking. This study aimed to assess the correlation between symptoms and CCv3...
August 8, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37602636/ramadan-fasting-model-exerts-hepatoprotective-anti-obesity-and-anti-hyperlipidemic-effects-in-an-experimentally-induced-nonalcoholic-fatty-liver-in-rats
#29
JOURNAL ARTICLE
Abeer A Alasmari, Abdulrahman S Al-Khalifah, Ahmed S BaHammam, Noura M S Alshiban, Ahmad T Almnaizel, Hesham S Alodah, Maha H Alhussain
BACKGROUND: The epidemic of nonalcoholic fatty liver disease (NAFLD) and its metabolic effects present a serious public health concern. We hypothesized that the Ramadan fasting model (RFM), which involves fasting from dawn to dusk for a month, could provide potential therapeutic benefits and mitigate NAFLD. Accordingly, we aimed to validate this hypothesis using obese male rats. METHODS: Rats were split into two groups (n = 24 per group), and they were given either a standard (S) or high-fat diet (HFD) for 12 weeks...
August 8, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37470635/an-algorithm-based-active-cleansing-protocol-can-reduce-the-bowel-preparation-time-for-screening-colonoscopy-a-propensity-score-matching-study
#30
JOURNAL ARTICLE
Fumiaki Ishibashi, Sho Suzuki, Ryu Tanaka, Konomi Kobayashi, Tomohiro Kawakami, Mizuki Nagai, Kentaro Mochida, Tetsuo Morishita
BACKGROUND: Methods that minimize the time for on-site bowel preparation before colonoscopy are needed. We prospectively validated that a novel algorithm-based active cleansing (ABAC) protocol could reduce the time for preparation compared with the conventional method. METHODS: This was an open-label, multicenter, prospective comparative study from April to October 2021. The study compared the bowel preparation time for colonoscopy between patients instructed with the ABAC protocol and control groups...
July 19, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37470634/clinical-and-pathological-characteristics-of-early-onset-colorectal-cancer-in-south-korea
#31
JOURNAL ARTICLE
Su Bee Park, Jin Young Yoon, Min Seob Kwak, Jae Myung Cha
BACKGROUND: Early-onset colorectal cancer (EOCRC) may differ by race and ethnicity, and recently South Korea has witnessed a surge in cases. We aimed to evaluate the clinical and pathological features of patients with EOCRC, and to determine the predictors of overall survival. METHODS: In this retrospective study, EOCRC was defined as CRC diagnosed in patients aged < 50 years, and late-onset CRC was defined as CRC diagnosed in those over 75 years of age. The clinical and pathological characteristics of patients with EOCRC were compared with late-onset CRC...
July 17, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37417191/association-between-smoking-and-colorectal-cancer-in-eastern-mediterranean-regional-office-emro-a-systematic-review-and-meta-analysis
#32
JOURNAL ARTICLE
Mohammad-Hossein Keivanlou, Ehsan Amini-Salehi, Soheil Hassanipour, Abinash Mahapatro, Nakka Raghuma, Farahnaz Joukar, Negin Letafatkar, Arman Habibi, Naeim Norouzi, Maryam Sadat Aleali, Mona Javid, Arian Mirdamadi, Fariborz Mansour-Ghanaei
BACKGROUND: Smoking poses a significant risk for colorectal cancer (CRC), considered the third leading reason for cancer-related deaths worldwide. However, there has been limited research on the relationship between smoking and CRC in the Eastern Mediterranean Regional Office (EMRO). Therefore, a meta-analysis was conducted to combine available data and gain a comprehensive understanding of the relationship between smoking and CRC in EMRO. METHODS: Two independent researchers searched PubMed, Scopus, and Web of Science until December 2022...
July 4, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37417192/long-term-health-and-economic-benefits-of-switching-to-tenofovir-alafenamide-versus-continuing-on-entecavir-in-chronic-hepatitis-b-patients-with-low-level-viremia-in-saudi-arabia
#33
JOURNAL ARTICLE
Faisal M Sanai, Mohammed Aljawad, Abdullah Saeed Alghamdi, Alon Yehoshua, Abdullah Khathlan, Mohammed Alghamdi, Sam Kozma, Nathaniel Smith, Fadoua El-Moustaid, Sushanth Jeyakumar, Nandita Kachru
BACKGROUND: Despite the success of current treatments, many chronic hepatitis B (CHB) patients still live with low-level viremia [LLV] resulting in liver disease progression. This study evaluated the long-term health and economic impact of switching to tenofovir alafenamide (TAF) from entecavir (ETV) in Saudi Arabia (SA) in chronic hepatitis B (CHB) LLV patients. METHODS: A hybrid decision tree Markov state-transition model was developed to simulate a cohort of patients with CHB LLV treated with ETV and switched to TAF over a lifetime horizon in SA...
June 30, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37417190/does-percutaneous-cholecystostomy-affect-prognosis-of-patients-with-acute-cholecystitis-that-are-unresponsive-to-conservative-treatment
#34
JOURNAL ARTICLE
Danny Hazan, Eyal Leibovitz, Muhamad Jazmawi, Mordechai Shimonov
BACKGROUND: Percutaneous cholecystostomy (PC) can be used as bridging or definitive therapy in some cases of acute cholecystitis. We aimed to compare hospital stay and survival of patients that underwent PC insertion because of acute calculus cholecystitis (ACC) compared to those who did not. METHODS: This is a retrospective study in which patients with gangrenous cholecystitis and perforation were excluded. Regression models were used to evaluate the influence of PC on mortality and hospital stay...
June 28, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37357494/effects-of-irritable-bowel-syndrome-on-the-health-related-quality-of-life-among-the-saudi-population
#35
JOURNAL ARTICLE
Emad S Aljahdli, Ftoon Badroun, Hanan H Mushaeb, Raghad Aljohani, Sara Albisher, Leena Basalaim, Salma Baeisa
BACKGROUND: Irritable bowel syndrome (IBS) is a digestive system disorder. Patients with IBS have a significantly lower quality of life (QoL). In this study, we aimed to assess how IBS affects the Saudi Arabian population's health-related (HR)-QoL. METHODS: A cross-sectional Web-based survey was conducted with a representative sample (n = 1346) of patients who met the Rome IV criteria for IBS from all regions of the country between February and May 2021. The questionnaire surveyed participants' socio-demographic data (nationality, sex, age, region, marital status, level of education, and occupation) and included 24 questions on IBS divided into four categories: (1) diagnosis; (2) symptoms; (3) impact on patients' lives; and (4) management methods...
June 22, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37338468/clinicopathological-and-prognostic-features-of-borrmann-type-iv-gastric-cancer-versus-other-borrmann-types-a-unique-role-of-signet-ring-cell-carcinoma
#36
JOURNAL ARTICLE
Chengcai Liang, Yao Liang, Biyi Ou, Lei Yuan, Shuqiang Yuan
BACKGROUND: Evidence specifically comparing the clinicopathology of Borrmann type IV (B-IV) gastric cancer with that of other Borrmann types is insufficient. METHODS: A total of 3130 patients with advanced gastric cancer who underwent gastrectomy from January 2001 to September 2017 were enrolled in the analysis. Logistic regression and survival analysis methodology were used to investigate factors associated with peritoneal metastasis and overall survival (OS). RESULTS: Of the total cohort, 264 (8...
June 16, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37313945/ibd-in-the-elderly-beware-of-pitfalls
#37
EDITORIAL
Mohmmed T Sharip, Sreedhar Subramanian
No abstract text is available yet for this article.
June 12, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37313944/ibd-disk-as-a-tool-estimating-the-prevalence-of-inflammatory-bowel-disease-related-disability-and-associated-influencing-factors-in-saudi-arabia-a-cross-sectional-study
#38
JOURNAL ARTICLE
Yaser Meeralam, Adnan B Al-Zanbagi, Mona Al Saedi, Walaa Alharthi, Hanadi A Sabbahi, Talal Alhejaili, Mohammed K Shariff
BACKGROUND: Inflammatory bowel disease (IBD) disk is an easy tool to use in clinical practice to measure IBD-related disability, with a score >40 correlating with high daily-life burden. Its use has been limited mainly to the western world. We aimed to estimate the prevalence of IBD-related disability and evaluate the associated risk factors in Saudi Arabia. METHODS: In this cross sectional study conducted at a tertiary referral center for IBD, the English IBD disk was translated into Arabic, and patients with IBD were approached to complete it...
June 8, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37282448/the-prevalence-and-clinical-characteristics-of-clostridium-difficile-infection-in-saudi-patients-admitted-with-inflammatory-bowel-disease-a-case-control-study
#39
JOURNAL ARTICLE
Abdulrahman AlKhormi, Abdullah M Altheyabi, Saud A AlGhamdi, Osama Alshahrani, Abdulwahed A Alotay, Ahmad Deeb
BACKGROUND: Inflammatory bowel disease (IBD) patients are at increased risk of Clostridium difficile infection (CDI), causing significant morbidity and mortality. This study examined CDI's prevalence, predisposing factors, and clinical outcomes in Saudi hospitalized IBD patients. METHODS: : A retrospective case-control study was conducted at a tertiary medical city in Riyadh, Saudi Arabia. All Saudi adult patients with IBD, admitted over the preceding four years were identified from the hospital's database...
May 31, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/37282447/frequency-and-predictive-factors-for-spontaneous-normalization-of-anti-tissue-transglutaminase-iga-serology-among-saudi-children-with-type-1-diabetes-mellitus-a-cohort-study
#40
JOURNAL ARTICLE
Ahmed Al Sarkhy, Ali Al Hassan, Heba Assiri, Hayfa Alabdulkarim, Noor AlAnazi, Nawaf Alshammari, Najla AlOtaibi, Mona Al Asmi, Asaad Assiri, Reem Al-Khalifah, Shaik Shaffi Ahamed, Mohammad El Mouzan
BACKGROUND: Celiac serology can be transiently elevated in patients with type 1 diabetes mellitus (T1DM) and normalized despite gluten consumption. This study aimed to identify the frequency and predictive factors of spontaneous normalization of anti-tissue transglutaminase (anti-TTG-IgA) antibodies in these patients. METHODS: The charts of all patients (≤18 years) with T1DM were retrospectively reviewed from 2012 to 2021 at a tertiary care center in Riyadh, Saudi Arabia...
May 31, 2023: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
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