journal
Journals Psychiatry and Clinical Neuros...

Psychiatry and Clinical Neurosciences

https://read.qxmd.com/read/37210704/therapeutic-outcomes-wide-association-scan-of-different-antipsychotics-in-patients-with-schizophrenia-randomized-clinical-trials-and-multi-ancestry-validation
#1
JOURNAL ARTICLE
Zhe Lu, Yuyanan Zhang, Yaoyao Sun, Yundan Liao, Zhewei Kang, Xiaoyang Feng, Hao Yan, Lifang Wang, Tianlan Lu, Dai Zhang, Weihua Yue
AIM: This study identified discrepant therapeutic outcomes of antipsychotics. METHODS: A total of 5191 patients with schizophrenia were enrolled, 3030 as discovery cohort, 1395 as validation cohort, and 766 as multi-ancestry validation cohort. Therapeutic Outcomes Wide Association Scan was conducted. Types of antipsychotics (one antipsychotic vs. other antipsychotics) were dependent variables, therapeutic outcomes including efficacy and safety were independent variables...
May 21, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37199263/corrigendum
#2
(no author information available yet)
No abstract text is available yet for this article.
May 18, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37178325/association-between-low-levels-of-anti-inflammatory-cytokines-during-pregnancy-and-postpartum-depression
#3
JOURNAL ARTICLE
Chiaki T Ono, Zhiqian Yu, Taku Obara, Mami Ishikuro, Keiko Murakami, Masahiro Kikuya, Saya Kikuchi, Natsuko Kobayashi, Hisaaki Kudo, Soichi Ogishima, Naoko Minegishi, Junichi Sugawara, Shinichi Kuriyama, Masayuki Yamamoto, Nobuo Yaegashi, Hiroaki Tomita
AIM: Previous studies based on a relatively limited number of subjects have indicated potential associations between plasma cytokine concentrations in perinatal women and postpartum depression (PPD). This report aimed to examine alterations in cytokine levels during pregnancy and after delivery by measuring nine cytokines in prenatal and postnatal plasma samples in a large cohort. METHODS: A nested, case-control study was conducted using plasma samples from 247 women with PPD (Edinburgh Postnatal Depression Scale: EPDS ≥9) and 243 age-matched control (EPDS ≤2) women from among perinatal women who participated in the Tohoku Medical Megabank three-generation cohort...
May 13, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37169515/l-theanine-combination-therapy-with-fluvoxamine-in-moderate-to-severe-obsessive-compulsive-disorder-a-placebo-controlled-double-blind-randomized-trial
#4
JOURNAL ARTICLE
Mehran Nematizadeh, Hossein Ghorbanzadeh, Hossein Sanjari Moghaddam, Mohammadreza Shalbafan, Mahsa Boroon, Amir-Abbas Keshavarz-Akhlaghi, Shahin Akhondzadeh
AIM: The main aim of this study was to investigate the additional effects of L-theanine, an amino acid in tea and an analog of glutamate with neuroprotective and anti-depressant properties, on obsessive-compulsive disorder (OCD) symptoms in combination with fluvoxamine. METHODS: Patients from either sex aged between 18-60 years diagnosed with OCD, based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), who had a Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score of more than 21 were enrolled in a double-blinded, parallel-group, placebo-controlled, clinical trial of 10 weeks to receive either L-theanine (100 mg twice daily) and fluvoxamine (100 mg daily initially followed by 200 mg daily after week 5) or placebo and fluvoxamine...
May 11, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37166682/high-sensitivity-c-reactive-protein-and-bilirubin-as-possible-biomarkers-for-hikikomori-in-depression-a-case-control-study
#5
LETTER
Sota Kyuragi, Toshio Matsushima, Matsuo Keitaro, Tomohiro Nakao, Takahiro A Kato
No abstract text is available yet for this article.
May 11, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37165609/parental-history-of-dementia-and-the-risk-of-dementia-a-cross-sectional-analysis-of-a-global-collaborative-study
#6
JOURNAL ARTICLE
Dae Jong Oh, Jong Bin Bae, Darren M Lipnicki, Ji Won Han, Perminder S Sachdev, Tae Hui Kim, Kyung Phil Kwak, Bong Jo Kim, Shin Gyeom Kim, Jeong Lan Kim, Seok Woo Moon, Joon Hyuk Park, Seung-Ho Ryu, Jong Chul Youn, Dong Young Lee, Dong Woo Lee, Seok Bum Lee, Jung Jae Lee, Jin Hyeong Jhoo, Ingmar Skoog, Jenna Najar, Therese R Sterner, Antonio Guaita, Roberta Vaccaro, Elena Rolandi, Nikolaos Scarmeas, Mary Yannakoulia, Mary H Kosmidis, Steffi G Riedel-Heller, Susanne Roehr, Jacqueline Dominguez, Ma Fe De Guzman, Krizelle Cleo Fowler, Antonio Lobo, Pedro Saz, Raul Lopez-Anton, Kaarin J Anstey, Nicolas Cherbuin, Moyra E Mortby, Henry Brodaty, Julian Trollor, Nicole Kochan, Ki Woong Kim
BACKGROUND: Parental history of dementia appears to increase the risk of dementia, but there have been inconsistent results. We aimed to investigate whether the association between parental history of dementia and the risk of dementia are different by dementia subtypes and sex of parent and offspring. METHODS: For this cross-sectional study, we harmonized and pooled data for 17,194 older adults from nine population-based cohorts of eight countries. These studies conducted face-to-face diagnostic interviews, physical and neurological examinations, and neuropsychological assessments to diagnose dementia...
May 10, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37144917/exome-wide-screening-identifies-novel-susceptibility-genes-for-subjective-well-being
#7
LETTER
Qingqing Cai, Chuyu Pan, Sirong Shi, Xiaoge Chu, Xiaoyue Qin, Dan He, Na Zhang, Yijing Zhao, Wenming Wei, Feng Zhang
No abstract text is available yet for this article.
May 5, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37133257/peritraumatic-distress-and-psychological-symptoms-in-people-infected-with-covid-19-after-the-easing-of-china-s-zero-covid-policy
#8
LETTER
Shifeng Li, Qiongying Xu
No abstract text is available yet for this article.
May 3, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37114655/changes-in-child-behavioral-problems-and-maternal-attachment-towards-children-with-attention-deficit-hyperactivity-disorder-following-behavioral-parent-training-a-pilot-study
#9
LETTER
Ayaka Ishii-Takahashi, Yuki Kawakubo, Junko Hamada, Naomi Nakajima, Takuya Kawahara, Akiko Hirose, Rio Yamaguchi, Hitoshi Kuwabara, Takashi Okada, Yukiko Kano
No abstract text is available yet for this article.
April 28, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37097074/gray-matter-reserve-determines-glymphatic-system-function-in-young-onset-alzheimer-s-disease-evidenced-by-dti-alps-and-compared-with-age-matched-controls
#10
JOURNAL ARTICLE
Hsin-I Chang, Chi-Wei Huang, Shih-Wei Hsu, Shu-Hua Huang, Kun-Ju Lin, Tsung-Ying Ho, Mi-Chia Ma, Wen-Chiu Hsiao, Chiung-Chih Chang
BACKGROUND: The diffusion tensor imaging analysis along the perivascular space (ALPS)-index can be used to model the glymphatic system in vivo. AIM: This study explores putative mechanisms between prediction of ALPS-index and cognitive outcomes in young-onset Alzheimer's disease (YOAD) and age-matched controls (CTLs) and analyze whether the link was mediated by the integrity of ALPS-index-anchored cerebral gray matter (GM). METHODS: We enrolled 130 patients with YOAD and 137 CTLs...
April 25, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37092883/circadian-variability-of-objective-sleep-measures-predicts-the-relapse-of-a-mood-episode-in-bipolar-disorder-findings-from-the-apple-cohort
#11
JOURNAL ARTICLE
Yuichi Esaki, Kenji Obayashi, Keigo Saeki, Kiyoshi Fujita, Nakao Iwata, Tsuyoshi Kitajima
AIM: Sleep disturbance, a core feature of bipolar disorder, is closely associated with mood symptoms. We examined the association between actigraphy sleep parameters and mood episode relapses in patients with bipolar disorder. METHODS: This prospective cohort study analyzed 193 outpatients with bipolar disorder who participated in the Association between the Pathology of Bipolar Disorder and Light Exposure in Daily Life (APPLE) cohort study. The participants' sleep was objectively evaluated via actigraphy over 7 consecutive days for the baseline assessment and then at the 2-year follow-up appointment for mood episode relapses...
April 24, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37070555/influence-of-cannabis-use-on-incidence-of-psychosis-in-people-at-clinical-high-risk
#12
JOURNAL ARTICLE
Lucy A Chester, Lucia R Valmaggia, Matthew J Kempton, Edward Chesney, Dominic Oliver, Emily P Hedges, Elise Klatsa, Daniel Stahl, Mark van der Gaag, Lieuwe de Haan, Barnaby Nelson, Patrick McGorry, G Paul Amminger, Anita Riecher-Rössler, Erich Studerus, Rodrigo Bressan, Neus Barrantes-Vidal, Marie-Odile Krebs, Birte Glenthøj, Merete Nordentoft, Stephan Ruhrmann, Gabriele Sachs, Philip McGuire
AIMS: Evidence for case-control studies suggests that cannabis use is a risk factor for the development of psychosis. However, there have been limited prospective studies and the direction of this association remains controversial. The primary aim of the present study was to examine the association between cannabis use and the incidence of psychotic disorders in people at clinical high risk of psychosis. Secondary aims were to assess associations between cannabis use and the persistence of psychotic symptoms, and with functional outcome...
April 18, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37052366/neuropsychopharmacology-renaissance-in-japan-a-new-era-after-the-crisis
#13
EDITORIAL
Norio Ozaki, Teiji Kimura, Tetsuro Kikuchi, Takeo Ishiyama
No abstract text is available yet for this article.
April 13, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37029954/resting-state-theta-phase-gamma-amplitude-coupling-as-a-biomarker-for-the-transdiagnostic-dimensional-approach-in-psychiatric-disorders
#14
LETTER
Minah Kim, Yurim Shim, Junbeom Kwon, Sangyoon Bae, Junhee Lee, Jiook Cha, Soo-Hee Choi, Se Hyun Kim, Ung Gu Kang, Jun Soo Kwon
No abstract text is available yet for this article.
April 8, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/37029644/discrimination-in-clinical-diagnosis-between-patients-with-schizophrenia-and-healthy-controls-using-eye-movement-and-cognitive-functions
#15
JOURNAL ARTICLE
Kosuke Okazaki, Kenichiro Miura, Junya Matsumoto, Naomi Hasegawa, Michiko Fujimoto, Hidenaga Yamamori, Yuka Yasuda, Manabu Makinodan, Ryota Hashimoto
AIM: Eye movements and cognitive functions are significantly impaired in schizophrenia. We aimed to develop promising clinical diagnostic markers that fit practical digital health applications in psychiatry using eye movement and cognitive function data from 1254 healthy individuals and 336 patients with schizophrenia. METHODS: Multivariate analyses using logistic regression were performed to confirm net performance of eye movements and cognitive functions scored using the Wechsler Adult Intelligence Scale Third Edition and Wechsler Memory Scale-Revised...
April 8, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/36992617/depression-and-lifestyle-focusing-on-nutrition-exercise-and-their-possible-relevance-to-molecular-mechanisms
#16
JOURNAL ARTICLE
Hiroshi Kunugi
Accumulating evidence has suggested the important role of lifestyle factors in depressive disorder. This paper aimed to introduce and outline recent research on epidemiological and intervention studies on lifestyle-related factors in depressive disorder with a special focus on diet. Evidence on exercise, sleep and related behaviors is also described. Here findings from meta-analytic studies are emphasized and related studies by the author's research group are introduced. Dietary factors that increase the risk of the illness include energy overload, skipping breakfast, unhealthy diet styles such as Western diet, inflammation-prone diet, and high consumption of ultra-processed food...
March 29, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/36974903/erratum
#17
(no author information available yet)
No abstract text is available yet for this article.
March 28, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/36949621/are-sleep-disturbances-a-cause-or-consequence-of-autism-spectrum-disorder
#18
JOURNAL ARTICLE
Takashi Yamada, Takeo Watanabe, Yuka Sasaki
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by core symptoms such as atypical social communication, stereotyped behaviors, and restricted interests. One of the comorbid symptoms of individuals with ASD is sleep disturbance. There are two major hypotheses regarding the neural mechanism underlying ASD, i.e., the excitation/inhibition (E/I) imbalance and the altered neuroplasticity hypotheses. However, the pathology of ASD remains unclear due to inconsistent research results. This paper argues that sleep is a confounding factor, thus, must be considered when examining the pathology of ASD because sleep plays an important role in modulating the E/I balance and neuroplasticity in the human brain...
March 22, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/36944556/moderation-effect-of-the-eveningness-chronotype-on-the-relationship-between-adhd-tendency-and-internet-addiction
#19
LETTER
Tomotaka Miyashita, Shunsuke Takagi, Sayuri Ishii, Nanase Kobayashi, Daisuke Jitoku, Sugihara Genichi, Hidehiko Takahashi
No abstract text is available yet for this article.
March 21, 2023: Psychiatry and Clinical Neurosciences
https://read.qxmd.com/read/36938718/neural-responses-to-emotional-stimuli-across-the-dissociative-spectrum-common-and-specific-mechanisms
#20
REVIEW
Marco Cavicchioli, Anna Ogliari, Cesare Maffei, Clara Mucci, Georg Northoff, Andrea Scalabrini
AIM: Departing from existing neurobiological models of dissociation, the current study aims at conducting a quantitative meta-analytic review of neural responses to emotional stimuli among individuals ascribed to the dissociative spectrum (DS). Accordingly, the study explored common and specific brain mechanisms across borderline personality disorder, conversion/somatoform disorders, posttraumatic stress disorder, posttraumatic stress disorder related to repeated interpersonal traumatic experiences, and dissociative disorders...
March 20, 2023: Psychiatry and Clinical Neurosciences
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