Journals Psychiatry and Clinical Neuros...

Psychiatry and Clinical Neurosciences
Sangni Liu, Dandan Fan, Cancan He, Xinyi Liu, Haisan Zhang, Hongxing Zhang, Zhijun Zhang, Chunming Xie
AIM: Childhood maltreatment (CM) is an important risk factor for major depressive disorder (MDD). This study aimed to explore the specific effect of CM on cerebral blood flow (CBF) and brain functional connectivity (FC) in MDD patients. METHODS: A total of 150 subjects were collected including 55 MDD patients with CM, 34 MDD patients without CM, 19 healthy controls (HC) with CM, and 42 HC without CM. All subjects completed MRI scans and neuropsychological tests...
October 2, 2023: Psychiatry and Clinical Neurosciences
Lorenzo Moccia, Michelangelo di Luzio, Eliana Conte, Marco Modica, Marianna Ambrosecchia, Martina Ardizzi, Pierluigi Lanzotti, Georgios D Kotzalidis, Delfina Janiri, Marco Di Nicola, Luigi Janiri, Vittorio Gallese, Gabriele Sani
Sense of agency (SoA) indicates a person's ability to perceive her/his own motor acts as actually being her/his and, through them, to exert control over the course of external events. Disruptions in SoA may profoundly affect the individual's functioning, as observed in several neuropsychiatric disorders. This is the first article to systematically review studies that investigated intentional binding (IB), a quantitative proxy for SoA measurement, in neurological and psychiatric patients. Eligible were studies of IB involving patients with neurological and/or psychiatric disorders...
September 26, 2023: Psychiatry and Clinical Neurosciences
Shangying Tsai, Martha Sajatovic, Pao-Huan Chen, Yu-Jui Huang, Kuo-Hsuan Chung
No abstract text is available yet for this article.
September 14, 2023: Psychiatry and Clinical Neurosciences
Shusei Arafuka, Hiroshige Fujishiro, Youta Torii, Hirotaka Sekiguchi, Chikako Habuchi, Ayako Miwa, Mari Yoshida, Shuji Iritani, Yasushi Iwasaki, Masashi Ikeda, Norio Ozaki
AIM: Clinical studies reported that patients with schizophrenia are at a higher risk of developing dementia than people without schizophrenia. However, early neuropathological studies have shown that the incidence of Alzheimer's disease (AD) in schizophrenia patients does not differ from that in controls. These inconsistent results may be attributable to the inclusion of non-AD dementia, but there have been few clinicopathological studies in older patients with schizophrenia based on the current neuropathological classification...
September 14, 2023: Psychiatry and Clinical Neurosciences
Naomi Hasegawa, Yuka Yasuda, Norio Yasui-Furukori, Hisashi Yamada, Hikaru Hori, Kayo Ichihashi, Yoshikazu Takaesu, Hitoshi Iida, Hiroyuki Muraoka, Fumitoshi Kodaka, Jun-Ichi Iga, Naoki Hashimoto, Kazuyoshi Ogasawara, Kazutaka Ohi, Kentaro Fukumoto, Shusuke Numata, Takashi Tsuboi, Masahide Usami, Akitoyo Hishimoto, Ryuji Furihata, Taishiro Kishimoto, Toshinori Nakamura, Eiichi Katsumoto, Shinichiro Ochi, Tatsuya Nagasawa, Kiyokazu Atake, Chika Kubota, Hiroshi Komatsu, Hirotaka Yamagata, Kenta Ide, Masahiro Takeshima, Mikio Kido, Saya Kikuchi, Tsuyoshi Okada, Junya Matsumoto, Kenichiro Miura, Taichi Shimazu, Ken Inada, Koichiro Watanabe, Ryota Hashimoto
AIM: This study aims to examine the real-world effectiveness of education regarding clinical guidelines for psychiatric disorders using 'the Effectiveness of guidelines for dissemination and education in psychiatric treatment (EGUIDE)' project. METHODS: The EGUIDE project is a nationwide prospective implementation study of two clinical practice guidelines, i.e., the Guideline for Pharmacological Therapy of Schizophrenia and the Treatment Guidelines for Major Depressive Disorders, in Japan...
September 8, 2023: Psychiatry and Clinical Neurosciences
(no author information available yet)
Retraction: [Noda Y, Sato A, Fujii K, Nagano Y, Iwasa M, Hirahata K, Kitahata R, Osawa R, A pilot study of the effect of transcranial magnetic stimulation treatment on cognitive dysfunction associated with post COVID-19 condition, Psychiatry Clin. Neurosci. 2023; 77: 241-242 (]. The above article from Psychiatry and Clinical Neurosciences, published online on 30 January 2023 in Wiley Online Library ( has been retracted by agreement between the authors, the Editors in Chief, Tadafumi Kato and Hidehiko Takahashi, and John Wiley & Sons Australia Ltd...
September 8, 2023: Psychiatry and Clinical Neurosciences
Shu-Xian Xu, Xin-Hui Xie, Lihua Yao, Wei Wang, Honghan Zhang, Mian-Mian Chen, Siqi Sun, Zhao-Wen Nie, Corina Nagy, Zhongchun Liu
AIM: This study aimed to investigate the neuroinflammatory hypothesis of depression and the potential anti-inflammatory effect of electroconvulsive therapy (ECT) in vivo, utilizing astrocyte-derived extracellular vesicles (ADEVs) isolated from plasma. METHODS: A total of 40 patients with treatment-resistant depression (TRD) and 35 matched healthy controls (HCs) were recruited at baseline, and 34 TRD patients completed the post-ECT visits. Blood samples were collected at baseline and post-ECT...
September 7, 2023: Psychiatry and Clinical Neurosciences
Huajie Di, Yi Wen
No abstract text is available yet for this article.
September 6, 2023: Psychiatry and Clinical Neurosciences
Marlene Pils, Julia Rutsch, Feride Eren, Göran Engberg, Fredrik Piehl, Simon Cervenka, Carl Sellgren, Svenja Troßbach, Dieter Willbold, Sophie Erhardt, Oliver Bannach, Carsten Korth
AIM: The Disrupted-in-schizophrenia 1 (DISC1) protein is a key regulator at the intersection of major signaling pathways relevant for adaptive behavior. It is prone to posttranslational changes such as misassembly and aggregation but the significance of such transformations for human mental illness has remained unclear. We aimed to demonstrate the occurrence of DISC1 protein aggregates in patients with first episode psychosis (FEP). METHOD: Cerebrospinal fluid (CSF) samples of patients with FEP (n = 50) and matched healthy controls (HC; n = 47) were measured by the highly sensitive surface-based fluorescence intensity distribution analysis (sFIDA) technology that enables single aggregate detection...
September 5, 2023: Psychiatry and Clinical Neurosciences
Ping-Tao Tseng, Bing-Syuan Zeng, Trevor Thompson, Brendon Stubbs, Po-Ren Hsueh, Kuan-Pin Su, Yen-Wen Chen, Tien-Yu Chen, Yi-Cheng Wu, Pao-Yen Lin, Andre F Carvalho, Chih-Wei Hsu, Dian-Jeng Li, Ta-Chuan Yeh, Cheuk-Kwan Sun, Yu-Shian Cheng, Yow-Ling Shiue, Chih-Sung Liang, Yu-Kang Tu
AIM: Many randomised controlled trials (RCTs) have investigated the use of interleukin-6 (IL-6) antagonists for the treatment of coronavirus disease 2019 (COVID-19), yielding inconsistent results. This network meta-analysis (NMA) aimed to identify the source of these inconsistent results by re-assessing whether participants treated with standard of care (SoC) plus placebo group have different all-cause mortality from those treated with SoC alone and to re-evaluate the efficacy of IL-6 antagonists in the treatment of COVID-19...
August 30, 2023: Psychiatry and Clinical Neurosciences
Jee In Kang, Jun Ho Seo, Chun Il Park, Shin Tae Kim, Yoon-Keun Kim, Jung-Kyu Jang, Cheol-O Kwon, Sumoa Jeon, Hae Won Kim, Se Joo Kim
AIM: The present study examined the microbiome abundance and composition of drug-naïve or drug-free patients with obsessive-compulsive disorder (OCD) compared to healthy controls. In addition, in the OCD group, the microbiome composition was compared between early-onset and late-onset OCD. METHODS: Serum samples were collected from 89 patients with OCD and 107 age- and sex-matched healthy controls. Bacterial DNA was isolated from bacteria-derived extracellular vesicles in serum and then amplified and quantified using primers specific to the V3-V4 hypervariable region of the 16S rDNA gene...
August 30, 2023: Psychiatry and Clinical Neurosciences
Jichun Yang, Yimin Qu, Yongle Zhan, Haihui Ma, Xiaoxiu Li, Dongmei Man, Hongguo Wu, Ping Huang, Liangkun Ma, Yu Jiang
BACKGROUND: Antepartum depression is a prevalent unhealthy mental health problem worldwide, particularly in low-income countries. It is a major contributor to adverse birth outcomes. Previous studies linking antepartum depression to birthweight have yielded conflicting results, which may be reason that the depressive symptoms were only measured once during pregnancy. This study aimed to explore the associations between trajectories of antepartum depressive symptoms and birthweight. METHODS: Depressive symptoms were assessed prospectively at each trimester in 3699 pregnant women from 24 hospitals across 15 provinces in China, using the Edinburgh Postpartum Depression Scale (EPDS)...
August 26, 2023: Psychiatry and Clinical Neurosciences
Naomi B Fine, Liat Helpman, Daphna Bardin Armon, Guy Gurevitch, Gal Sheppes, Zivya Seligman, Talma Hendler, Miki Bloch
AIM: Childhood sexual abuse (CSA) among women is an alarmingly prevalent traumatic experience, that often leads to debilitating and treatment-refractory Post-Traumatic Stress Disorder (PTSD) raising the need for novel adjunctive therapies. Neuroimaging investigations systematically report amygdala hyperactivity is the most consistent and reliable neural abnormality in PTSD and childhood abuse, raising the potential of implementing volitional neural modulation using neurofeedback (NF) aimed at down-regulating amygdala activity...
August 24, 2023: Psychiatry and Clinical Neurosciences
Szu-Wei Cheng, Chung-Wen Chang, Wan-Jung Chang, Hao-Wei Wang, Chih-Sung Liang, Taishiro Kishimoto, Jane Pei-Chen Chang, John S Kuo, Kuan-Pin Su
ChatGPT has sparked extensive discussions within the healthcare community since its November 2022 release. However, potential applications in the field of psychiatry have received limited attention. Deep learning has proven beneficial to psychiatry, and GPT is a powerful deep learning-based language model with immense potential for this field. Despite the convenience of ChatGPT, this advanced chatbot currently has limited practical applications in psychiatry. It may be used to support psychiatrists in routine tasks such as completing medical records, facilitating communications between clinicians and with patients, polishing academic writings and presentations, and programming and performing analyses for research...
August 23, 2023: Psychiatry and Clinical Neurosciences
Toshiharu Iida, Mizue Tanaka, Yohei Kawasaki, Shinichi Oka, Hiroyuki Shichino
No abstract text is available yet for this article.
August 22, 2023: Psychiatry and Clinical Neurosciences
Yuan Cao, Paulo Lizano, Gaoju Deng, Huan Sun, Xiaoqin Zhou, Hongsheng Xie, Yaru Zhan, Jingshi Mu, Xipeng Long, Hongqi Xiao, Shiyu Liu, Qiyong Gong, Changjian Qiu, Zhiyun Jia
AIM: Elevated inflammation and larger choroid plexus (ChP) volume has been previously identified in mood disorders. Connections between inflammation, ChP, and clinical symptoms in bipolar II depression (BDII-D) are unclear. Data-driven clustering based on neuroanatomical phenotypes may help to elucidate neurobiological associations in BDII-D. METHODS: Inflammatory cytokines, clinical symptoms, and neuroanatomical features were assessed in 150 BDII-D patients...
August 16, 2023: Psychiatry and Clinical Neurosciences
Emma A van Reekum, Julia J Woo, Jo-Anne Petropoulos, Zainab Samaan, Lawrence Mbuagbaw
AIM: To determine whether, in people with pre-existing obsessive-compulsive, eating, anxiety, and mood disorders, the COVID-19 pandemic was associated with a change in psychiatric symptoms, compared to pre-pandemic levels. METHODS: We searched MEDLINE, CINAHL, PsychINFO, and EMBASE from inception until February 16th, 2022. Studies were included if they reported pre-pandemic and during-pandemic psychiatric symptoms, using validated scales, in people with pre-existing mood, anxiety, eating, or obsessive-compulsive disorders...
August 11, 2023: Psychiatry and Clinical Neurosciences
Junghan Lee, Kyung Won Chang, Hyun Ho Jung, Dre Kim, Jin Woo Chang, Dong Ho Song
AIM: Deep brain stimulation (DBS) is one option for treating refractory TS; however, it remains unclear which preoperative factors are predictive of DBS outcomes. This study investigated the efficacy of DBS targeting the anteromedial globus pallidus internus (amGPi) and evaluated predisposing factors affecting the outcomes of DBS in a single center in Korea. METHOD: Twenty patients who had undergone DBS for refractory TS were reviewed retrospectively. Tic symptoms were followed up at 3-months intervals for up to 1 year after surgery...
August 10, 2023: Psychiatry and Clinical Neurosciences
Ryoko Okazaki, Toshihiko Nagata, Yuri Okamoto, Ichiro Mizuta, Noriko Yamamoto, Takahiro Tokunaga, Tatsuhisa Yamashita, Yoshimasa Urasaki, Hirotaka Kosaka
No abstract text is available yet for this article.
August 10, 2023: Psychiatry and Clinical Neurosciences
Chong Chen, Ryo Okubo, Sumiyo Okawa, Kosuke Hagiwara, Tomohiro Mizumoto, Naoko Higuchi, Shin Nakagawa, Takahiro Tabuchi
No abstract text is available yet for this article.
August 3, 2023: Psychiatry and Clinical Neurosciences
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