Journals Journal of the Formosan Medica...

Journal of the Formosan Medical Association
Chen-Hua Liu, Yih-Sharng Chen, Meng-Kun Tsai, Sheoi-Shen Wang, Chih-Yuan Lee, Chuan-I Tsao, Chun-Jen Liu, Tung-Hung Su, Tai-Chung Tseng, Shang-Chin Huang, Jo-Hsuan Wu, Pei-Jer Chen, Jia-Horng Kao
Data are limited regarding the long-term durability of sustained virologic response (SVR) in solid organ transplant recipients who achieve SVR12 with direct-acting antivirals (DAAs) for hepatitis C virus (HCV). We reported the virologic outcomes in 42 recipients who received DAAs for acute or chronic HCV infection after heart, liver, and kidney transplantation. After achieving SVR12 , all recipients received HCV RNA surveys at SVR24 , and biannually until the last visit. If HCV viremia was detected during the follow-up period, direct sequencing and phylogenetic analysis were performed to confirm late relapse or reinfection...
March 18, 2023: Journal of the Formosan Medical Association
Heng-Ching Liao, Fang-Ju Lin, Chien-Ning Hsu, Susan Shur-Fen Gau, Chi-Chuan Wang
This study documented the prescribing patterns of methylphenidate and atomoxetine among patients aged 3 to 18 in Taiwan diagnosed with attention deficit hyperactivity disorder (ADHD) between 2004 and 2017. Initial treatment for ADHD, the time between the first diagnosis and the first prescription, and medication-switching patterns were investigated. The final cohort consisted of 256,882 patients, and 147,210 (57.3%) of them received medication treatment. Most of the patients (98.2%) received methylphenidate...
March 15, 2023: Journal of the Formosan Medical Association
Melanie Kapapa, Daniela Weber, Alexandre Serra
BACKGROUND: An Oesophageal atresia (OA) affects almost 1 in 3500 newborn and its aetiology for development between 4th to 6th pregnancy weeks had not yet been clarified. METHODS: This retrospective, observational control group-supported (n = 30) examination was performed with OA mothers (n = 20) who were interrogated via specialized questionnaires and interviews to evaluate data on medical pregnancy history including hormonal treatment, changing of life habits (nutrition, diet, medication), drug consumption (alcohol, smoking, illicit drugs) as well as exposure to nuclear waste or poisonous substance exposition...
March 14, 2023: Journal of the Formosan Medical Association
Cheng-Chiang Liu, Jian-Pei Huang
BACKGROUND: The level of vitamin D in pregnant women and the effect of vitamin D supplementation are lack in Taiwan. OBJECTIVE: To investigate the vitamin D serum level and the effect of its supplementation on pregnancy. METHODS: We included 1048 pregnant women who underwent prenatal exam with known serum 25-hydroxyvitamin D3 [25(OH)D3] levels and delivery at the Mackay Memorial Hospital, Taipei, Taiwan during 2015-2018. A daily dose 2000 IU of vitamin D was given, starting at 12-16 weeks of pregnancy, to reach the level of 20 ng/mL, and then a maintenance dose of 800 IU/day was given...
March 14, 2023: Journal of the Formosan Medical Association
Chien-Hui Hung, Han-Ying Chen, Jessica Kang, Yi-Yun Tai, Shin-Yu Lin, Chien-Nan Lee
BACKGROUND: The rate of induction of labour has increased over the decades and numerous medications are available in the market. This study compares the efficacy and safety between dinoprostone slow-release pessary (Propess) and dinoprostone tablet (Prostin) for labour induction at term in nulliparous women. METHODS: This was a prospective single-blind randomized controlled trial conducted in a tertiary medical centre in Taiwan from September 1, 2020 to February 28, 2021...
March 10, 2023: Journal of the Formosan Medical Association
Pao-Yu Chen, Jann-Tay Wang, Sui-Yuan Chang, Chien-Ching Hung, Chi-Tai Fang, Aristine Cheng, Wang-Da Liu, Yu-Shan Huang, Kuan-Yin Lin, Hsin-Yun Sun, Sung-Ching Pan, Yu-Cheng Cheng, Hurng-Yi Wang, Wang-Huei Sheng, Yee-Chun Chen, Yi-Lwun Ho, Ming-Shiang Wu, Shan-Chwen Chang
BACKGROUND: COVID-19 rebound is usually reported among patients experiencing concurrent symptomatic and viral rebound. But longitudinal viral RT-PCR results from early stage to rebound of COVID-19 was less characterized. Further, identifying the factors associated with viral rebound after nirmatrelvir-ritonavir (NMV/r) and molnupiravir may expand understanding of COVID-19 rebound. METHODS: We retrospectively analyzed clinical data and sequential viral RT-PCR results from COVID-19 patients receiving oral antivirals between April and May, 2022...
March 8, 2023: Journal of the Formosan Medical Association
Chrong-Reen Wang, Wei-Chieh Lin
No abstract text is available yet for this article.
March 8, 2023: Journal of the Formosan Medical Association
Shin-Yi Lin, Yen-Bin Liu, Li-Ting Ho, Yu-Fong Peng, Ching-Hua Kuo, Sung-Chun Tang, Chih-Fen Huang, Jiann-Shing Jeng
BACKGROUND/PURPOSE: Amiodarone increases exposure of direct oral anticoagulants (DOACs). We aimed to analyze the effects of concurrent amiodarone use on DOAC concentrations and clinical outcomes. METHODS: Patients who were ≥20 years of age, had atrial fibrillation, and took DOAC were enrolled to provide trough and peak samples for DOAC concentration measurements using ultra-high-performance liquid chromatography-tandem mass spectrometry. The results were compared with concentrations reported in clinical trials to define above, within, or under the expected range...
March 6, 2023: Journal of the Formosan Medical Association
Chun-Jui Huang, Lin-Hsuan Lee, Cheng-Pin Cheng, Harn-Shen Chen, Chii-Min Hwu, Kam-Tsun Tang, Chiao-Wei Shih, Chang-Ching Yeh, Fan-Fen Wang, Chen-Chang Yang
BACKGROUND: Urinary iodine concentration (UIC) measured by Sandell-Kolthoff spectrophotometric method has been used in the Nutrition and Health Surveys in Taiwan but this method is time consuming and produces toxic waste from arsenic trioxide. The aim of this study was to develop and validate an inductively coupled plasma mass spectrometry (ICP-MS) system to determine UIC in Taiwan. METHODS: Samples and iodine calibrators were diluted 100-fold into an aqueous solution containing Triton X-100, 0...
March 4, 2023: Journal of the Formosan Medical Association
Jie Cheng, Kai Huang, Juan-Li Mou, Yao-Jia Lao, Jia-Hui Feng, Fan Hu, Meng-Lu Lin, Tangnuer Maimaitiaishan, Jian Shang, Jun Lin
BACKGROUND AND PURPOSE: Emerging researches have regarded serum chloride as a capable predictor of mortality in liver cirrhosis. We aim to investigate the clinical role of admission chloride in cirrhotic patients with esophagogastric varices receiving transjugular intrahepatic portosystemic shunt (TIPS), which is unclear. METHODS: We retrospectively analyzed data of cirrhotic patients with esophagogastric varices undergoing TIPS in Zhongnan Hospital of Wuhan University...
March 4, 2023: Journal of the Formosan Medical Association
Meng-Ju Lin, Tung-Hung Su, Chun-Jen Liu, Hung-Chih Yang, Chi-Ling Chen, Jyh-Ming Liou, Tai-Chung Tseng, Chen-Hua Liu, Chun-Ming Hong, Pei-Jer Chen, Jia-Horng Kao
BACKGROUND/PURPOSE: Distinct hepatitis relapse has been observed after discontinuing entecavir (ETV) or tenofovir disoproxil fumarate (TDF) therapy in chronic hepatitis B (CHB) patients. End-of-therapy (EOT) serum cytokines were compared and used for outcome prediction. METHODS: A total of 80 non-cirrhotic CHB patients in a tertiary medical center in Taiwan who discontinued ETV (n = 51) or TDF (n = 29) therapy after fulfilling the APASL guidelines were prospectively enrolled...
March 3, 2023: Journal of the Formosan Medical Association
Tsung-Chia Chen
No abstract text is available yet for this article.
March 2, 2023: Journal of the Formosan Medical Association
Chih-Horng Wu, Ming-Chih Ho, Jia-Horng Kao, Cheng-Maw Ho, Tung-Hung Su, Shih-Jer Hsu, Hsiang-Yun Huang, Chun-Yu Lin, Po-Chin Liang
BACKGROUND: Sarcopenia is a common finding in patients with decompensated cirrhosis without effective therapy. We aimed to examine whether a transjugular portosystemic shunt (TIPS) could improve the abdominal muscle mass assessed by cross-sectional images in patients with decompensated cirrhosis and to investigate the association of imaging-defined sarcopenia with the prognosis of such patients. METHODS: In this retrospective observational study, we enrolled 25 Decompensated cirrhosis patients aged >20 who received TIPS for the control of variceal bleeding or refractory ascites between April 2008 and April 2021...
March 1, 2023: Journal of the Formosan Medical Association
Zhi-Ye Yu, Chun-Fu Lai, Tai-Shuan Lai, Shao-Yu Yang, Shih-I Chen, Mei-Jun Lai, Chun-Min Kang, Yu-Tsung Huang, Yi-Ting Chen, Po-Ren Hsueh, Yung-Ming Chen, Shuei-Liong Lin
BACKGROUND: Patients with chronic kidney disease are at high risk for coronavirus disease 2019. Little is known about immune response to severe acute respiratory syndrome coronavirus 2 vaccination in patients on peritoneal dialysis (PD). METHOD: We prospectively enrolled 306 PD patients receiving two doses of vaccines (ChAdOx1-S: 283, mRNA-1273: 23) from July 2021 at a medical center. Humeral and cellular immune responses were assessed by anti-spike IgG concentration and blood T cell interferon-γ production 30 days after vaccination...
February 28, 2023: Journal of the Formosan Medical Association
Yu-Cheng Lu, Kao-Lang Liu, Vin-Cent Wu, Shuo-Meng Wang, Yen-Hung Lin, Shih-Chieh Jeff Chueh, Kwan-Dun Wu, Yann-Rong Su, Kuo-How Huang
PURPOSE: Mineralocorticoid receptor antagonists are the first-line treatment for bilateral adrenal hyperplasia (BAH) with primary aldosteronism (PA), while unilateral adrenalectomy is the standard treatment for aldosterone-producing adenoma (APA). In this study, we investigated the outcomes of patients with BAH after unilateral adrenalectomy and compared them with those of patients with APA. METHODS: From January 2010 to November 2018, 102 patients with a diagnosis of PA confirmed by adrenal vein sampling (AVS) and available NP-59 scans were enrolled...
February 20, 2023: Journal of the Formosan Medical Association
Ting-Yen Kuo, Ming-Chieh Hsieh, Chia-Dan Cheng, Ren-Yeong Huang, Thomas E Van Dyke, Cheng-En Sung, Chen-Ying Wang, Yi-Shing Hsieh, Wan-Chien Cheng
OBJECTIVES: This study aimed to evaluate the impact of chlorhexidine (CHX) gel on inflammation-induced periodontal tissue destruction, osteoclastogenesis, subgingival microbiota, and on the modulation of the RANKL/OPG as well as inflammatory mediators during bone remodeling in vivo. MATERIALS AND METHODS: Ligation- and LPS injection-induced experimental periodontitis were created to investigate the effect of topical application of CHX gel in vivo. Alveolar bone loss, osteoclast number and gingival inflammation was evaluated by micro-CT, histological, immunohistochemistry and biochemical analysis...
February 17, 2023: Journal of the Formosan Medical Association
Cheng-Kuang Yang, Tai-Lung Cha, Yen-Hwa Chang, Shu-Pin Huang, Jen-Tai Lin, Shian-Shiang Wang, Chao-Yuan Huang, See-Tong Pang
Darolutamide, a second-generation androgen receptor inhibitor (SGARI), has been shown to increase metastasis-free survival and overall survival among men with non-metastatic castration-resistant prostate cancer (nmCRPC). Its unique chemical structure potentially provides efficacy and safety advantages over the SGARIs apalutamide and enzalutamide, which are also indicated for nmCRPC. Despite a lack of direct comparisons, the SGARIs appear to have similar efficacy, safety, and quality of life (QoL) results. Indirect evidence suggests that darolutamide is preferred for its good adverse event profile, an attribute valued by physicians, patients, and their caregivers for maintaining QoL...
February 14, 2023: Journal of the Formosan Medical Association
Kai-Chieh Chang, Hsin-Shui Chen, Chi-Shin Wu, Chin-Kai Chang, Juey-Jen Hwang, Su-Hua Huang, Yung-Ming Chen, Bor-Wen Cheng, Min-Hsiu Weng, Chih-Cheng Hsu, Wei-Lieh Huang
INTRODUCTION: Social participation activities have a close association with health aging. However, the clinical significance of numbers of social participation activities and its cutoff value has not been defined. METHODS: We recruited 516 people aged ≥55 years. Twelve social participation behaviors modified according to Taiwanese culture were investigated, and the adequacy of cutoff number was determined by the area under the receiver operating characteristic curve (AUC) according to the results of cluster analysis of individual activities and scores of the Brief Symptom Rating Scale-5 (BSRS-5) and the Chinese Happiness Inventory (CHI)...
February 12, 2023: Journal of the Formosan Medical Association
Chia-Hao Hu, Li-Yu Chiang, Shen-Mao Hsu, Chien-Yuan Lin, Kuen-Fu Liaw
No abstract text is available yet for this article.
February 12, 2023: Journal of the Formosan Medical Association
Ta-Wei Tai, Chun-Feng Huang, Huei-Kai Huang, Rong-Sen Yang, Jung-Fu Chen, Tien-Tsai Cheng, Fang-Ping Chen, Chung-Hwan Chen, Yin-Fan Chang, Wei-Chieh Hung, Der-Sheng Han, Ding-Cheng Chan, Ching-Chou Tsai, I-Wen Chen, Wing P Chan, Husan-Jui Chang, Jawl-Shan Hwang, Chih-Hsing Wu
Osteoporosis greatly increases the risk of fractures. Osteoporotic fractures negatively impact quality of life, increase the burden of care, and increase mortality. Taiwan is an area with a high prevalence of osteoporosis. This updated summary of guidelines has been developed by experts of the Taiwan Osteoporosis Association with the intention of reducing the risks of osteoporotic fractures and improving the quality of care for patients with osteoporosis. The updated guidelines compile the latest evidence to provide clinicians and other healthcare professionals with practical recommendations for the prevention, diagnosis, and management of osteoporosis under clinical settings in Taiwan...
February 11, 2023: Journal of the Formosan Medical Association
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