Sun Jae Park, Minseo Kim, Seogsong Jeong, Young Jun Park, Seulggie Choi, Jooyoung Chang, Yun Hwan Oh, Sun Wook Cho, Young Joo Park, Sang Min Park
Background: Although recent studies have introduced antibiotics as a potential risk factor for thyroid cancer, further studies are necessary. We examined the association between long-term antibiotic usage and thyroid cancer risk. Methods: This nationwide cohort study investigated 9,804,481 individuals aged 20 years or older who participated in health screening (2005-2006) with follow-up ending on December 31, 2019, using the Korean National Health Insurance Service database. Multivariable Cox proportional hazards regression was used to estimate adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) for thyroid cancer risk according to the cumulative days of antibiotic prescription and the number of antibiotic classes, respectively...
December 18, 2023: Thyroid: Official Journal of the American Thyroid Association