Adela D Mattiazzi, Alexandra Centeno, Alexandra Amador, Casiana Fernandez-Bango, Catherine Dillard Scowby, Marian O'Rourke, Tamieka Hill-Matthie, Ronak Patel, Frances Barrios, Phillip Ruiz, Linda Chen, Junichiro Saghesima, Gaetano Ciancio, George W Burke, Michael Goldstein, Jayanthi Chandar, Gabriel Contreras, David Roth, Warren Kupin, Giselle Guerra, Rodrigo Vianna
BACKGROUND: Transplantation continues to be challenging in highly sensitized patients. Herein, we compared induction immunosuppression (IS) based on immunologic risk stratification and desensitization with intravenous immunoglobulin (IVIG). METHODS: Of the 42 highly sensitized kidney and 3 kidney-pancreas transplant recipients who underwent IVIG for desensitization from 2008-2014, 10 (Control group) received standard induction IS with antithymocyte globulin, basiliximab, and methylprednisolone, and 35 (Rituximab group) received standard IS with rituximab ± IVIG ± plasmapheresis...
2014: Clinical Transplants