Monsurul Hoq, Susan Matthews, Susan Donath, John Carlin, Vera Ignjatovic, Paul Monagle
Establishing paediatric reference intervals (RIs) is a challenging task due to difficulties in subject recruitment, collection of adequate blood volume, and the inherent physiological changes of many biomarkers with age. Despite these challenges, several national and international initiatives have demonstrated: (a) the feasibility of prospectively designed paediatric RI studies; (b) the development of continuous RIs; and (c) the comparison of reference values across analyser types to harmonise paediatric RIs...
May 2020: Clinical Biochemist. Reviews