Kristina Sandgren, Sara N Strandberg, Joakim H Jonsson, Josefine Grefve, Angsana Keeratijarut Lindberg, Erik Nilsson, Anders Bergh, Karin Söderkvist, Camilla Thellenberg Karlsson, Bengt Friedrich, Anders Widmark, Lennart Blomqvist, Vibeke Berg Loegager, Jan Axelsson, Mattias Ögren, Margareta Ögren, Tufve Nyholm, Katrine Riklund
OBJECTIVE: PET/CT and multiparametric MRI (mpMRI) are important diagnostic tools in clinically significant prostate cancer (csPC). The aim of this study was to compare csPC detection rates with [68Ga]PSMA-11-PET (PSMA)-PET, [11C]Acetate (ACE)-PET, and mpMRI with histopathology as reference, to identify the most suitable imaging modalities for subsequent hybrid imaging. An additional aim was to compare inter-reader variability to assess reproducibility. METHODS: During 2016-2019, all study participants were examined with PSMA-PET/mpMRI and ACE-PET/CT prior to radical prostatectomy...
August 24, 2023: Nuclear Medicine Communications