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Lasers in Surgery and Medicine | Page 2

Sarathkumar Loganathan, Soundarapandian Santhanakrishnan, Ravi Bathe, Muthukumaraswamy Arunachalam
BACKGROUND AND OBJECTIVES: The employability of the non-invasive femtosecond laser ablation technique for dental treatment has been severely limited by its low ablation rate despite the advantage of minimal tissue damage. The study explores a means of improving the femtosecond laser ablation rate and efficiency by physiochemical surface modification. MATERIALS AND METHODS: Surface modification of dental hard tissues has been carried out by food graded orthophosphoric acid and Carie care gel pretreatment...
June 5, 2019: Lasers in Surgery and Medicine
Kamila Pasternak-Mnich, Barbara Ziemba, Aleksandra Szwed, Karolina Kopacz, Marek Synder, Maria Bryszewska, Jolanta Kujawa
BACKGROUND AND OBJECTIVES: We have investigated how low intensity laser irradiation emitted by a multiwave-locked system (MLS M1) affects the viability and proliferation of human bone marrow mesenchymal stem cells (MSCs) depending on the parameters of the irradiation. STUDY DESIGN/MATERIALS AND METHODS: Cells isolated surgically from the femoral bone during surgery were identified by flow cytometry and cell differentiation assays. For irradiation, two wavelengths (808 and 905 nm) with the following parameters were used: power density 195, 230, and 318 mW/cm 2 , doses of energy 3, 10, and 20 J (energy density 0...
June 4, 2019: Lasers in Surgery and Medicine
Christine Petti, Jacqueline Stoneburner
BACKGROUND AND OBJECTIVES: Liposuction has become increasingly popular in the past decade due to advances in technique and technology. Despite the demand, there exists a significant population of patients who have contour deformities post-liposuction. The 1,060 nm diode laser has been Food and Drug Administration approved for the removal of unwanted fat, so it was theorized that this noninvasive laser system could be efficacious to smooth these areas of post-liposuction contour deformities...
June 4, 2019: Lasers in Surgery and Medicine
Ying Wang, Raquel Ferrer-Espada, Yan Baglo, Ying Gu, Tianhong Dai
BACKGROUND AND OBJECTIVES: The aim of this study was to investigate the efficacy, safety, and mechanism of action of antimicrobial blue light (aBL) for the inactivation of Neisseria gonorrhoeae, the etiological agent of gonorrhea. STUDY DESIGN/MATERIALS AND METHODS: The susceptibilities of N. gonorrhoeae (ATCC 700825) in planktonic suspensions to aBL at 405- and 470-nm wavelengths were compared. The roles of oxygen in the anti-gonococcal activity of aBL were studied by examining the effects of hypoxic condition (blowing N2 ) on the anti-gonococcal efficiency of 405-nm aBL...
June 3, 2019: Lasers in Surgery and Medicine
Adel Zeidan, Dukho Do, Dongkyun Kang, Mitsuhiro Ikuta, Jiheun Ryu, Guillermo J Tearney
BACKGROUND AND OBJECTIVE: Spectrally encoded endoscopy (SEE) is an optical imaging technology that uses spatial wavelength multiplexing to conduct endoscopy in miniature, small diameter probes. Contrary to the previous side-viewing SEE devices, forward-viewing SEE probes are advantageous as they provide a look ahead that facilitates navigation and surveillance. The objective of this work was to develop a miniature forward-viewing SEE probe with a wide field of view and a high spatial resolution...
May 26, 2019: Lasers in Surgery and Medicine
Bin Zhang, Yan Chu, Zigang Xu, Yujuan Sun, Li Li, Xiaofeng Han, Chen Wang, Li Wei, Yuanxiang Liu, Lin Ma
BACKGROUND AND OBJECTIVES: Café-au-lait spots, also known as café-au-lait macules (CALMs), are a common pigmentary disorder. Although various laser modalities have been used to treat CALMs, the efficacy of laser treatment in children differs from that in adults. We investigated the efficacy, safety, and clinical factors of the treatment of CALMs using Q-switched alexandrite laser (755 nm) therapy in children. METHODS: In total, 471 children with CALMs underwent Q-switched alexandrite laser therapy at a treatment interval of 3-12 months...
May 25, 2019: Lasers in Surgery and Medicine
Allison C Hu, Ellen M Hong, Omar Toubat, Ryan Sivoraphonh, Christian Barnes, Wesley J Moy, Tatiana B Krasieva, Brian J F Wong
OBJECTIVES: Injury to healthy dermis and the dermoepidermal junction initiates a robust healing process consisting of fibrous tissue overgrowth, collagen deposition, and scar formation. The conventional management of scars and other skin injuries has largely relied upon surgical soft tissue transfer to resurface and/or replace damaged and dysmorphic tissue with new skin. However, these strategies are invasive, expensive, and may further exacerbate integumentary injury. In this study, we examine the creation of in situ redox generated pH changes in fresh human skin...
May 24, 2019: Lasers in Surgery and Medicine
Guillermo J Tearney, Thomas D Wang, Dongkun Kang
No abstract text is available yet for this article.
May 22, 2019: Lasers in Surgery and Medicine
Mandy W M Chan, Samantha Yee-Nam Shek, Chi Keung Yeung, Henry Hin-Lee Chan
BACKGROUND AND OBJECTIVE: To evaluate safety and efficacy of treatment with the picosecond Nd:YAG 532 nm for lentigines in Asian skin. STUDY DESIGN/MATERIALS AND METHODS: This was a prospective, open-label cohort study, using a novel picosecond 532-nm laser for the treatment of facial lentigines. Subjects received up to three laser treatments every 4-6 weeks and were assessed at 4 and 12 weeks after final treatment. Primary endpoint was degree of improvement in lentigines at 12 weeks after the final treatment, assessed by treating investigator based on Physicians Global Assessment...
May 21, 2019: Lasers in Surgery and Medicine
Afshan Shirkavand, Shirin Farivar, Ezeddin Mohajerani, Leila Ataie-Fashtami, Mohammad H Ghazimoradi
BACKGROUND AND OBJECTIVE: Optical reflectance spectroscopy is a non-invasive technique for optical characterization of biological samples. Any alteration in a cell from normal or carcinogenic causes will change its refractive index. The aim of this study is to develop a computerized program for extraction of a refractive index of normal and cancerous skin cell lines, including melanoma, fibroblast, and adipose cells, using visible near-infrared reflectance spectra and the Kramers-Kronig (K-K) relations...
May 15, 2019: Lasers in Surgery and Medicine
Tao Ma, Yi-Chao Chai, Hao-Yang Zhu, Huan Chen, Yue Wang, Qing-Shan Li, Li-Hui Pang, Rong-Qian Wu, Yi Lv, Ding-Hui Dong
BACKGROUND AND OBJECTIVE: Despite the successful application of laser in animal experiments and clinics, the adjustment of laser parameters during surgery is still unclear. This study aimed to investigate the effect of different 980-nm diode laser parameters in hepatectomy. This could provide a clear protocol for using 980-nm diode laser in hepatectomy. STUDY DESIGN/MATERIALS AND METHODS: In total, 48 Sprague-Dawley rats were used to explore the effects of different 980-nm diode laser parameters in hepatectomy, by setting different parameter combinations...
May 14, 2019: Lasers in Surgery and Medicine
Christine Sofie Krohn Fuchs, Christiane Bay, Maurice Adatto, Hans Lomholt, Merete Haedersdal
BACKGROUND AND OBJECTIVE: Recently, a novel acne treatment based on selective photothermolysis of pilosebaceous units with follicular delivery of inert gold microparticles as an exogenous chromophore and diode laser pulses has been developed. To evaluate the efficacy and safety of a single monotherapy treatment regimen with gold microparticles and diode laser exposure in patients with moderate and moderately severe acne. Further, to evaluate the added benefit of a second treatment regimen combined with pharmaceutical acne treatment in patients with inadequate initial response...
May 14, 2019: Lasers in Surgery and Medicine
Abel Swaan, Christophe K Mannaerts, Berrend G Muller, Rob Aa van Kollenburg, Marit Lucas, C Dilara Savci-Heijink, Ton G van Leeuwen, Theo M de Reijke, Daniel M de Bruin
OBJECTIVE: To demonstrate the safety and feasibility of clinical in vivo needle-based optical coherence tomography (OCT) imaging of the prostate. MATERIALS AND METHODS: Two patients with prostate cancer underwent each two percutaneous in vivo needle-based OCT measurements before transperineal template mapping biopsy. The OCT probe was introduced via a needle and positioned under ultrasound guidance. To test the safety, adverse events were recorded during and after the procedure...
May 14, 2019: Lasers in Surgery and Medicine
Alexander A Daoud, Chloe Gianatasio, Ashley Rudnick, Mary Michael, JillS Waibel
BACKGROUND AND OBJECTIVES: Scar rehabilitation is a complex process that incorporates medical, surgical, and physical therapeutic measures to best restore function and visual normalcy. Lasers have emerged as essential tools in the management of scars, with devices available to address scar size, dyschromia, and contour irregularities. As different lasers treat these different features, multi-laser, same session therapeutic approaches may offer a more comprehensive approach to scar revision...
May 14, 2019: Lasers in Surgery and Medicine
Jianfang Rong, Liang Zhang, Wangdi Liao, Yong Xie, Nonghua Lu, Xu Shu
BACKGROUND AND OBJECTIVE: Confocal laser endomicroscopy (CLE) is a novel endoscopic technique that can image cells and subcellular layers of the gastric mucosa in vivo. We aimed to investigate the value of CLE in assessing the quality of ulcer healing (QOUH) and preliminarily establish evaluation criteria. MATERIALS AND METHODS: Patients with duodenal ulcers were enrolled. After duodenal ulcer healing, we compared the value of CLE and white light endoscopy (WLE) in assessing the QOUH by using the histopathological diagnosis as the gold standard...
May 10, 2019: Lasers in Surgery and Medicine
Marcus Wurlitzer, Elisabeth Hessling, Karsten Rinas, MarcelineManka Fuh, Hannes Petersen, Franz Ricklefs, Katrin Lamszus, Jan Regelsberger, Stephanie Maier, Sebastian Kruber, Nils-Owe Hansen, RJDwayne Miller, Hartmut Schlüter
BACKGROUND AND OBJECTIVES: A picosecond infrared laser (PIRL) has recently been demonstrated to cut biological tissue without scar formation based on the minimal destructive action on the surrounding cells. During cutting with PIRL, the irradiated tissue is ablated by a cold vaporization process termed desorption by impulsive vibrational excitation. In the resulting aerosol, all molecules are dissolved in small droplets and even labile biomolecules like proteins remain intact after ablation...
May 8, 2019: Lasers in Surgery and Medicine
Gary Peterson, Daniella Karassawa Zanoni, Marco Ardigo, Jocelyn C Migliacci, Snehal G Patel, Milind Rajadhyaksha
BACKGROUND: Reflectance confocal microscopy (RCM) is a developing approach for noninvasive detection of oral lesions with label-free contrast and cellular-level resolution. For access into the oral cavity, confocal microscopes are being configured with small-diameter telescopic probes and small objective lenses. However, a small probe and objective lens allows for a rather small field-of-view relative to the large areas of tissue that must be examined for diagnosis. To extend the field-of-view for intraoral RCM imaging, we are investigating a video-mosaicking approach...
May 8, 2019: Lasers in Surgery and Medicine
Elisabeth Russe, Gottfried Wechselberger, Karl Schwaiger, Klemens Heinrich, Michaela Hladik, Heike Traintinger
OBJECTIVES: Extracorporeal shockwave therapy (ESWT) has been demonstrated as a feasible noninvasive method to improve wound healing. This effect was demonstrated to result from increased perfusion and angiogenesis due to systemic growth factor expression. We, therefore, hypothesized that preoperative ESWT reduces scar formation after surgery. METHODS: A prospective, controlled pilot study on 24 patients undergoing abdominoplasty was conducted and the efficacy of preoperative unfocused, low energy EWST was evaluated...
April 29, 2019: Lasers in Surgery and Medicine
Yunyoung C Chang, Jennifer Croix, Srimanasi Javvaji, Shannon Hernandez, Anne M Chapas, Jennifer MacGregor
PURPOSE: Microfocused ultrasound (MFUS) is a safe and effective method for noninvasive skin tightening. Previous clinical studies demonstrate a 60-100% patient satisfaction after MFUS. We used an anonymous online platform after MFUS to assess patient satisfaction. DESIGN: Patients treated with MFUS between January 2013 and 2016 were invited to complete an anonymous online survey at least 4 months post-treatment. Patients were asked to rate improvement in skin tightening as none (0%), mild (0-25%), moderate (26-50%), significant (51-75%), or dramatic (76-100%) and treatment satisfaction as disappointed, neutral, satisfied, or extremely satisfied...
August 2019: Lasers in Surgery and Medicine
Luke A Hardy, Viktoriya Vinnichenko, Nathaniel M Fried
OBJECTIVES: The experimental Thulium fiber laser (TFL) is currently being studied as a potential alternative to the gold standard Holmium:YAG laser for lithotripsy. Recent advances in both Holmium and TFL technology allow operation at similar laser parameters for direct comparison. The use of a "dusting" mode with low pulse energy (0.2-0.4 J) and high pulse rate (50-80 Hz) settings, is gaining popularity in lithotripsy due to the desire to produce smaller residual stone fragments during ablation, capable of being spontaneously passed through the urinary tract...
August 2019: Lasers in Surgery and Medicine
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