J L Woodruff, M K Bykalo, F Z Loyo-Rosado, E S Maissy, A T Sadek, M Hersey, J M Erichsen, N D Maxwell, M A Wilson, S K Wood, P Hashemi, C A Grillo, L P Reagan
The complications of obesity extend beyond the periphery to the central nervous system (CNS) and include an increased risk of developing neuropsychiatric co-morbidities like depressive illness. Preclinical studies support this concept, including studies that have examined the effects of high-fat diet (HFD) on depressive-like behaviors. Although women are approximately two-fold more likely to develop depressive illness compared to men, most preclinical studies have focused on the effects of HFD in male rodents...
April 30, 2024: Appetite