M E R Chierato, V B V Silveira, D F P Pavani, W O Fahl, K Iamamoto, K M Asano, H B C R Batista, K C Scheffer, P C Maiorka, E Mori
Rabies, a fatal zoonotic viral disease affecting mammals, including humans, remains a significant global health concern, particularly in low-income countries. The disease, primarily transmitted through infected animal saliva, prompts urgent diagnosis for timely post-exposure prophylaxis (PEP). The gold standard diagnostic test, direct fluorescent antibody test (dFAT), while sensitive, suffers from limitations such as subjective interpretation and high costs. As a confirmatory technique, the LN34 Pan-Lyssavirus RT-qPCR assay has emerged as a promising tool for universal Lyssavirus detection...
May 6, 2024: Journal of Virological Methods