journal
https://read.qxmd.com/read/36948266/the-anti-tumor-effects-of-celastrus-orbiculatus-thunb-and-its-monomer-composition-a-review
#1
REVIEW
Xinyi Feng, Zixin Yin, Shiya Ou, Zewen Chu, Jun Feng, Yuanyuan Luo, Yaqi Hu, Yanqing Liu, Wei Jiang, Xiaoqing Wang, Haibo Wang
ETHNOPHARMACOLOGICAL RELEVANCE: Celastrus orbiculatus Thunb. has been included in "The Plant List" (http://www. theplantlist.org) and is the most widely researched species in its genus. It is called Nanshe Teng in China. Celastrus orbiculatus Thunb. is a plant of Euonymus and it's medicinal part is the vine and stem. It is also called Alias Dragon grass, Yellow Yine, etc. It has good anti-tumor, anti-inflammatory and other effects. More and more studies have shown that Celastrus orbiculatus Thunb...
March 20, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36948265/rhus-chinensis-mill-fruits-alleviate-liver-injury-induced-by-isoniazid-and-rifampicin-through-regulating-oxidative-stress-apoptosis-and-bile-acid-transport
#2
JOURNAL ARTICLE
Yilin Sun, Yuanyue Zhang, Nan Ma, Shengbao Cai
ETHNOPHARMACOLOGICAL RELEVANCE: Rhus chinensis Mill. is a species of the genus Rhus belonging to the family Anacardiaceae. Its fruits used to treat/prevent liver related diseases (e.g., jaundice and hepatitis) in folk medicine. Otherwise, the effects and underlying mechanisms of the fruits on the prevention of isoniazid and rifampicin-caused liver injury have not been investigated. AIM OF THE STUDY: To study the preventive effects and mechanisms of the Rhus chinensis Mill...
March 20, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36948264/panaxytriol-upregulates-cyp3a4-expression-through-the-interaction-between-nuclear-regulators-and-dna-response-elements
#3
JOURNAL ARTICLE
Jingdi Yan, Qi Gu, Chao Meng, Jianming Liu, Fanglan Liu, Chunhua Xia
ETHNOPHARMACOLOGICAL RELEVANCE: Cytochrome P3A4 (CYP3A4) is a crucial drug-metabolizing enzyme, and its expression is regulated by the pregnane X receptor (PXR), constitutive androstane receptor (CAR), steroid receptor coactivator 1 (SRC-1), and acetyltransferase P300. Panaxytriol is a naturally derived active substance extracted from the roots of Panax ginseng C. A. Mey. which is widely used clinically. Our previous studies have shown that panaxytriol induces CYP3A4 expression through PXR activation, which is antagonized by high CAR expression...
March 20, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36948263/chamomile-essential-oils-exert-anti-inflammatory-effects-involving-human-and-murine-macrophages-evidence-to-support-a-therapeutic-action
#4
JOURNAL ARTICLE
Paola De Cicco, Giuseppe Ercolano, Carmina Sirignano, Valentina Rubino, Daniela Rigano, Angela Ianaro, Carmen Formisano
ETHNOPHARMACOLOGICAL RELEVANCE: Chamomile (M. chamomilla L.) is an herbaceous plant from family Astereaceae, that has a long history of use in traditional medicine. It has been used as herbal remedies for thousands of years to treat several diseases, including infections, neuropsychiatric, respiratory, gastrointestinal, and liver disorders. Chronic inflammation is involved in the pathogenesis of most infectious and non-infectious diseases and macrophages are considered the major cellular players that drive disease initiation and maintenance...
March 20, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36948262/traditional-uses-chemical-compositions-and-pharmacological-activities-of-dendrobium-a-review
#5
REVIEW
Pei-Yuan Li, Li Li, Yuan-Zhong Wang
ETHNOPHARMACOLOGICAL RELEVANCE: Dendrobium is a kind of medicine food homology plant. Dendrobium has long been used to strengthen "Yin" and tonify five viscera. AIM OF THIS REVIEW: This paper presents a systematic review of the folk usage, chemical composition and pharmacological activity of Dendrobium, aiming to provide a reference for subsequent in-depth understanding and better exploitation of health food, medicine, and natural products. MATERIALS AND METHODS: Available information about the genus Dendrobium was collected via Web of Science, PubMed, Science Direct, Scopus, APA-Psy Articles, Google Scholar, Connected Papers, Springer Search, and KNCI...
March 20, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36940737/fufang-shengdi-mixture-alleviates-psoriasis-like-skin-inflammation-via-promoting-annexin-a-proteins-expression
#6
JOURNAL ARTICLE
Xiaoying Zhou, Chunming Lyu, Xingmi Chen, Yuhan Ye, Yuanyuan Lei, Ying Liu, Tong Zhang, Yang Yang
ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Chinese medicine believes that "blood fever" is an important cause of psoriasis. Fufang Shengdi mixture (FFSD), based on the Hongban Decoction, is composed of Rehmannia glutinosa (Gaertn.) DC., Raw gypsum (Chinese: Sheng Shi Gao), and Lonicera japonica Thunb (Caprifoliaceae). FFSD has effects on nourishing Yin, clearing heat, connecting collaterals, and cooling blood. In modern medical explanation, FFSD has the effects of anti-inflammatory and immunosuppression...
March 18, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36940736/component-identification-of-modified-sanmiao-pills-by-uplc-xevo-g2-xs-qtof-and-its-anti-gouty-arthritis-mechanism-based-on-network-pharmacology-and-experimental-verification
#7
JOURNAL ARTICLE
Ruyi Chen, Fenfen Li, Kai Zhou, Mengyu Xing, Xiaoxi Zhang, Xinyu Zhao, Chenxi Wu, Ziwei Han, Yixuan Zhou, Li Yan, Daozong Xia
ETHNOPHARMACOLOGICAL RELEVANCE: Modified sanmiao pills (MSMP), a traditional Chinese medicine (TCM) formula, is consisted of rhizome of Smilax glabra Roxb., Cortexes of Phellodendron chinensis Schneid., rhizome of Atractylodes chinensis (DC.) Koidz., and roots of Cyathula officinalis Kuan. in a ratio of 3:3:2:1. This formula has been broadly applied to treat gouty arthritis (GA) in China. AIMS OF THE STUDY: To elaborate the pharmacodynamic material basis and pharmacological mechanism of MSMP against GA...
March 18, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36940735/intestinal-escherichia-coli-and-related-dysfunction-as-potential-targets-of-traditional-chinese-medicine-for-respiratory-infectious-diseases
#8
REVIEW
Lini Wei, Lulu Zhang, Yan Zhang, Lan Yan, Bin Liu, Zhiwen Cao, Ning Zhao, Xiaojuan He, Li Li, Cheng Lu
ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Chinese medicine (TCM) has saved countless lives and maintained human health over its long history, especially in respiratory infectious diseases. The relationship between the intestinal flora and the respiratory system has been a popular research topic in recent years. According to the theory of the "gut-lung axis" in modern medicine and the idea that "the lung stands in an interior-exterior relationship with the large intestine" in TCM, gut microbiota dysbiosis is a contributing factor to respiratory infectious diseases, and there is potential means for manipulation of the gut microbiota in the treatment of lung diseases...
March 18, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36934787/bupleurum-chinense-exerts-a-mild-antipyretic-effect-on-lps-induced-pyrexia-rats-involving-inhibition-of-peripheral-tnf-%C3%AE-production
#9
JOURNAL ARTICLE
Yuan Kang, Yuan Gao, Ximeng Li, Xinwei Guo, Zhuangzhuang Liu, Wenjing Li, Jianhe Wei, Yun Qi
ETHNOPHARMACOLOGICAL RELEVANCE: Bupleuri Radix, the dried roots of Bupleurum chinense DC. (BC) or Bupleurum scorzonerifolium Willd., is one of the most frequently used traditional Chinese medicines. As the species in Xiao-Chai-Hu decoction, BC has been used as an antipyretic medicine with a long history. However, its antipyretic characteristics and underlying mechanism(s) remain unclear. AIM OF THE STUDY: To elucidate the antipyretic characteristics and mechanism(s) of BC used in its traditional way...
March 17, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36933876/therapeutic-potential-and-industrial-applications-of-terminalia-arjuna-bark
#10
REVIEW
Vikas Kumar, Nitin Sharma, Rakshandha Saini, Smita Mall, Gokhan Zengin, Anuradha Sourirajan, Prem Kumar Khosla, Kamal Dev, Mohamed El-Shazly
ETHNOPHARMACOLOGICAL RELEVANCE: Terminalia arjuna (Roxb. ex DC.) Wight & Arnot (Combretaceae) is one of the most frequently used medicinal trees in Indian traditional medicinal systems. It is used for the treatment of a variety of diseases including cardiovascular disorders. AIM OF THE STUDY: The purpose of this review was to provide a comprehensive overview of the phytochemistry, medicinal uses, toxicity, and industrial applications of T. arjuna bark (BTA), as well as to identify gaps in research and applications of this important tree...
March 16, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36933875/a-plantaginis-semen-coptidis-rhizoma-compound-alleviates-type-2-diabetic-mellitus-in-mice-via-modulating-ages-rage-pathway
#11
JOURNAL ARTICLE
Pei Liu, Xing Yan, Jiaying Pu, Qi Liao, Kang Wang, Jiping Lan, Rui Wang, Zhengtao Wang, Lili Ding, Li Yang
ETHNOPHARMACOLOGICAL RELEVANCE: Plantaginis Semen-Coptidis Rhizoma Compound(CQC) was first recorded in Shengji Zonglu. Clinical and experimental studies have reported that both of Plantaginis Semen and Coptidis Rhizoma exerted the effects of lowering blood glocose and lipid. However, the potential mechanism of CQC on type 2 diabetes (T2DM) remain unclear. AIM OF THE STUDY: The main objective of our investigation was to explore the mechanisms of CQC on T2DM based on network pharmacology and experimental research...
March 16, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36933874/pien-tze-huang-attenuated-acetaminophen-induced-liver-injury-by-autophagy-mediated-nlrp3-inflammasome-inhibition
#12
JOURNAL ARTICLE
Ruowei Zhao, Qing Zhang, Wenjing Liu, Yifan Lin, Yuhui He, Dennis Chang, Shaohua Li, Wen Xu, Yanxiang Lin, Yanfang Zheng, Xian Zhou, Mingqing Huang
ETHNOPHARMACOLOGICAL RELEVANCE: Pien Tze Huang is a classic traditional Chinese medicinal product, used for inflammatory diseases as stated in China Pharmacopoeia. In particular, it is effective in treating liver diseases and pro-inflammatory conditions. Acetaminophen (APAP) is a widely used analgesic drug, but its over-dose is associated with acute liver failure where the clinical approved antidote treatment is limited. Inflammation has been considered as one of the therapeutic targets against APAP-induced liver injury...
March 16, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36933873/the-potential-mechanism-of-qinghua-quyu-jianpi-decoction-in-the-treatment-of-ulcerative-colitis-based-on-network-pharmacology-and-experimental-validation
#13
JOURNAL ARTICLE
Fanfan Qu, Danyan Li, Shengsheng Zhang, Chenchen Zhang, Aihua Shen
ETHNOPHARMACOLOGICAL RELEVANCE: Ulcerative colitis (UC) is a chronic and recurrent inflammation of the gastrointestinal tract. Following the idea of herbal property and compatibility, a traditional Chinese medicine (TCM) formula consists of a number of TCM herbs. Qinghua Quyu Jianpi Decoction (QQJD) has been clinically proven to be effective in treating UC, however, its therapeutic mechanism has not been fully elucidated. AIM OF STUDY: Here, we used network pharmacology analysis and ultra-performance liquid chromatography-tandem mass spectrometry to predict the mechanism of action of QQJD, and then validated our predictions through in vivo and in vitro experiments...
March 16, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36933872/jiawei-yanghe-decoction-suppresses-breast-cancer-by-regulating-immune-responses-via-jak2-stat3-signaling-pathway
#14
JOURNAL ARTICLE
Yanting You, Xiaomei Chen, Xiaohu Chen, Hong Li, Ruisi Zhou, Jie Zhou, Meilin Chen, Baizhao Peng, Shuai Ji, Hiu Yee Kwan, Lifang Zou, Jingtao Yu, Yanyan Liu, Yifen Wu, Xiaoshan Zhao
ETHNOPHARMACOLOGICAL RELEVANCE: Jiawei Yanghe Decoction (JWYHD) is a widely used traditional Chinese medicine prescription in the clinical setting for the treatment of autoimmune diseases. Many studies showed that JWYHD has anti-tumor activities in cell and animal models. However, the anti-breast cancer effects of JWYHD and the underlying mechanisms of action remain unknown. AIM OF STUDY: This study aimed to determine the anti-breast cancer effect and reveal the underlying mechanisms of action in vivo, in vitro and in silico...
March 16, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36931413/ethanol-extract-of-propolis-regulates-type-2-diabetes-in-mice-via-metabolism-and-gut-microbiota
#15
JOURNAL ARTICLE
Rui Guan, Ning Ma, Guolong Liu, Qiu Wu, Shufang Su, Jun Wang, Yue Geng
ETHNOPHARMACOLOGICAL RELEVANCE: Propolis is a traditional natural medicine with various activities such as antioxidant and anti-inflammatory, immunomodulatory, anti-tumour, gastroenteritis treatment and prevention, anti-microbial and parasitic, as well as glucose regulation and anti-diabetes, and is expected to be an anti-diabetic candidate with few side effects, but the mechanism of action of propolis on type 2 diabetes mellitus (T2DM) has not been fully elucidated. AIM OF THE STUDY: The purpose of this study was to investigate the mechanism of the effect of ethanol extract of propolis (EEP) on the regulation of blood glucose in T2DM mice...
March 15, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36931412/yinma-jiedu-granule-attenuates-lps-induced-acute-lung-injury-in-rats-via-suppressing-inflammation-level
#16
JOURNAL ARTICLE
Gen Li, Jingwei Ma, Yang Yang, Caixia Zang, Cheng Ju, Fangyu Yuan, Jingwen Ning, Meiyu Shang, Qiuzhu Chen, Yueqi Jiang, Fangfang Li, Xiuqi Bao, Degui Mu, Dan Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: Yinma Jiedu Granule (YMJD) is a traditional Chinese patent medicine (CPM), which has been proved to have anti-inflammatory effects and therapeutical effects on obstructive pulmonary disease. AIM OF STUDY: The purpose of the current investigation is to find out if YMJD can alleviate acute lung injury (ALI) induced by lipopolysaccharide (LPS) in rats and its underlying mechanisms. MATERIALS AND METHODS: Rats were treated with either vehicle or YMJD for 14 consecutive days, and two hours after the last administration, the rat model of ALI was induced by the intratracheal instillation of LPS...
March 15, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36931411/an-evaluation-of-the-qualitative-superiority-of-the-mongolian-medicinal-herb-hurdan-tsagaan-platycodi-radix-from-five-different-geographic-origins-based-on-anti-inflammatory-effects
#17
JOURNAL ARTICLE
Qin Si, Longga Su, Dong Wang, Bao-Jun De, Risu Na, Nagongbilige He, Tserentsoo Byambaa, Tserendagva Dalkh, Xilinqiqige Bao, Letai Yi
ETHNOPHARMACOLOGICAL RELEVANCE: The contents and types of the active compounds in medicinal herbs depend greatly on their extraction methods, sources of origin and the modes of cultivation. Platycodon grandiflorus (Jacq.) A.DC. is an ethnic medicinal herb widely cultivated in China, and its dried root, Platycodi Radix (PR), is an important ingredient in herbal formulae for attenuating lung issues in Mongolian medical practice. However, research evaluating the superiority of PR based on harvesting regions is relatively limited...
March 15, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36924865/anti-tyrosinase-and-antimelanogenic-effect-of-cinnamic-acid-derivatives-from-prunus-mahaleb-l-phenolic-composition-isolation-identification-and-inhibitory-activity
#18
JOURNAL ARTICLE
Zühal Bayrakçeken Güven, Iclal Saracoglu, Akito Nagatsu, Mustafa Abdullah Yilmaz, A Ahmet Basaran
ETHNOPHARMACOLOGICAL RELEVANCE: The traditional use of Prunus species against skin diseases and especially for skin lightning cosmeceutical purposes is widespread in many cultures. Prunus mahaleb L. is a well known food plant and used in the baking industry for flavoring. The fruit kernels (endocarp) are used in India for hyperpigmentation. AIM OF THE STUDY: To investigate the chemical composition with the antimelanogenesis effect of P. mahaleb seed and kernel extracts and isolated compounds...
March 14, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36924864/jian-yan-ling-capsules-ameliorate-cognitive-impairment-in-mice-with-d-galactose-induced-senescence-and-inhibit-the-oxidation-induced-apoptosis-of-ht22-hippocampal-cells-by-regulating-the-nrf2-ho1-signaling-pathway
#19
JOURNAL ARTICLE
Qianyin Lou, Xue-Er Meng, Chongqi Wei, Jiaxiang Tong, Yang Chen, Mengting Li, Qingqing Wang, Sheng Guo, Jin-Ao Duan, Er-Xin Shang, Yue Zhu
ETHNOPHARMACOLOGICAL RELEVANCE: The Jian-Yan-Ling (JYL) capsule is a famous anti-aging Chinese patent medicine. It is applied mainly to delay senescence to improve cognition in aging individuals. However, the action mechanisms of JYL for improving cognition have not been determined. AIM OF THE STUDY: We will evaluate the effect of the JYL capsule at improving the cognition of aging mice by improving oxidative stress in the hippocampus and exploring its action mechanism...
March 14, 2023: Journal of Ethnopharmacology
https://read.qxmd.com/read/36924863/network-pharmacology-and-experimental-verification-to-explore-the-anti-migraine-mechanism-of-yufeng-ningxin-tablet
#20
JOURNAL ARTICLE
Shangyue Yu, Fan Chunlan, Li Yilin, Pei Hailuan, Tian Yingying, Zuo Zeping, Wang Zijian, Liu Chuang, Zhao Xinyue, Wang Zhibin
ETHNOPHARMACOLOGICAL RELEVANCE: Yufeng Ningxin Tablet (YNT) is a traditional Chinese medicine formula, that has been used clinically to treat migraine for many years. It is composed of one herb Pueraria lobata var. lobata (Willd.) Ohwi (Relevant Chinese name: Gegen). Previously, it has been recorded by traditional Chinese doctor that Gegen could be used as medicine to treat migraine. However, the underlying mechanism of action remains to be investigated. AIM OF THE STUDY: It was to explore the effect and mechanism of YNT on migraine based on network pharmacology and experimental verification...
March 14, 2023: Journal of Ethnopharmacology
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