Gen Li, Jingwei Ma, Yang Yang, Caixia Zang, Cheng Ju, Fangyu Yuan, Jingwen Ning, Meiyu Shang, Qiuzhu Chen, Yueqi Jiang, Fangfang Li, Xiuqi Bao, Degui Mu, Dan Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: Yinma Jiedu Granule (YMJD) is a traditional Chinese patent medicine (CPM), which has been proved to have anti-inflammatory effects and therapeutical effects on obstructive pulmonary disease. AIM OF STUDY: The purpose of the current investigation is to find out if YMJD can alleviate acute lung injury (ALI) induced by lipopolysaccharide (LPS) in rats and its underlying mechanisms. MATERIALS AND METHODS: Rats were treated with either vehicle or YMJD for 14 consecutive days, and two hours after the last administration, the rat model of ALI was induced by the intratracheal instillation of LPS...
March 15, 2023: Journal of Ethnopharmacology