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Margaret Rees, Irene Lambrinoudaki, Antonio Cano, Tommaso Simoncini
No abstract text is available yet for this article.
January 30, 2019: Maturitas
Claudio Di Lorito, Kristian Pollock, Rowan Harwood, Roshan das Nair, Pip Logan, Sarah Goldberg, Vicky Booth, Kavita Vedhara, Veronika Van Der Wardt
INTRODUCTION: Research has established that exercise and physical activity can improve executive functioning, independence and quality of life in people with dementia. A dedicated theory explaining behaviour change in relation to physical activity in people with dementia does not exist. We aimed to develop a theoretical model which can be used to inform effective interventions to promote physical activity in people with dementia. METHODS: There were five phases: 1...
January 23, 2019: Maturitas
Sarah Chapman, Lynda Ware
No abstract text is available yet for this article.
December 23, 2018: Maturitas
Panayotes Demakakos
No abstract text is available yet for this article.
December 6, 2018: Maturitas
Violante Di Donato, Michele Carlo Schiavi, Valentina Iacobelli, Ottavia D'oria, Evangelos Kontopantelis, Tommaso Simoncini, Ludovico Muzii, Pierluigi Benedetti Panici
OBJECTIVE: To evaluate the tolerability and safety of ospemifene in treating dyspareunia associated with postmenopausal vulvo- vaginal atrophy (VVA). METHODS: The literature was searched through to 31 July 2018 to identify randomized controlled trials comparing ospemifene 60 mg against placebo for the treatment of VVA. Two groups of outcomes were selected: 1) side-effects, including hot flushes, urinary tract infection (UTI), headache, deep venous thrombosis (DVT), coronary heart disease (CHD), cardiovascular event (CVE), discontinuation due to side-effects, serious adverse event (SAE); 2) Safety, in relation to endometrial thickness, vaginal bleeding, breast tenderness, breast and endometrial cancer...
November 28, 2018: Maturitas
Violante Di Donato, Michele Carlo Schiavi, Valentina Iacobelli, Ottavia D'oria, Evangelos Kontopantelis, Tommaso Simoncini, Ludovico Muzii, Pierluigi Benedetti Panici
OBJECTIVE: To evaluate the efficacy of ospemifene in treating dyspareunia associated with postmenopausal vulvo-vaginal atrophy (VVA). METHODS: A structured search was carried out in PubMed-Medlin, Embase, Cochrane Controlled Trials Register databases through to 31 July 2018. The search included the following terms: "Ospemifene", "vulvovaginal atrophy", "dyspareunia", "SERM" and "randomized controlled trial" (RCTs)...
November 24, 2018: Maturitas
Dolores Sánchez-Rodríguez, Cédric Annweiler, Tommy Cederholm
No abstract text is available yet for this article.
November 22, 2018: Maturitas
Ji-Eun Kim, Jaesung Choi, JooYong Park, Jong-Koo Lee, Aesun Shin, Sang Min Park, Daehee Kang, Ji-Yeob Choi
A lack of estrogen due to menopause changes metabolic homeostasis, which increases the risk of metabolic syndrome (MetS) in postmenopausal women. Hormone therapy (HT) has beneficial effects on chronic diseases as well as on menopause symptoms. The aim of this study was to investigate the association of HT use with MetS and its components by diabetes status in middle-aged postmenopausal Korean women. A cross-sectional analysis was undertaken of a total of 39,295 non-diabetic and 3,359 diabetic postmenopausal women aged 40 to 69 years from the Health Examinees-Gem (HEXA-G) study (2004-2013)...
March 2019: Maturitas
D A E Bolton, S E Schwartz, M Mansour, G Rydalch, D W McDannald
Merely viewing objects within reachable space can activate motor cortical networks and potentiate movement. This holds potential value for smooth interaction with objects in our surroundings, and could offer an advantage for quickly generating targeted hand movements (e.g. grasping a support rail to maintain stability). The present study investigated if viewing a wall-mounted safety handle resulted in automatic activation of motor cortical networks, and if this effect changes with age. Twenty-five young adults (18-30 years) and seventeen older adults (65+ years) were included in this study...
March 2019: Maturitas
Neha Pathak, Rageshri Dhairyawan, Shema Tariq
Intimate partner violence (IPV) against women is a significant public health issue globally. It has serious physical and psychological health consequences as well huge economic and social costs. With an ageing population globally, it is important to understand how older women experience IPV. We present a narrative review of 48 studies exploring IPV in women aged ≥45 years, focusing on: (1) prevalence of IPV; (2) factors associated with IPV; (3) impact of IPV; (4) responses to IPV; (5) IPV interventions; and (6) key populations...
March 2019: Maturitas
Natasha Aparecida Grande de França, Lavanya Srinivasa Murthy, Steven Phu, Elizabeth Liberts, Sara Vogrin, Ligia Araujo Martini, Gustavo Duque
OBJECTIVES: A high level of parathyroid hormone (PTH) was recently identified as a risk factor for falling. As balance instability is one of the major risk factors for falls, we aimed to investigate whether high PTH concentrations are associated with poor balance in older persons. STUDY DESIGN: Cross-sectional study with 127 community-dwelling older adults (75% female), aged 65-96 years, at the Falls and Fracture Clinic, Western Health-Sunshine Hospital, Melbourne, Australia...
March 2019: Maturitas
David Facal, Ana Maseda, Arturo X Pereiro, Manuel Gandoy-Crego, Laura Lorenzo-López, Javier Yanguas, José C Millán-Calenti
OBJECTIVE: To analyze the definition of "cognitive frailty" and to study the conceptual and operational definitions used and their implications for empirical research. The relationships between this concept and cognitive reserve, the role of neuropathology and brain reserve, motor signs of aging and the reversibility of cognitive frailty are also discussed. STUDY DESIGN: Systematic review of empirical studies identified from Medline Advanced 1966, CINAHL, Web of Science, PsycINFO, and Scopus until August 2017...
March 2019: Maturitas
Toshiyuki Yasui, Yuki Ideno, Yoko Onizuka, Junko Nakajima-Shimada, Jung-Su Lee, Hiromitsu Shinozaki, Mikiko Kishi, Reiko Suzuki, Kunihiko Hayashi
Results of studies on the associations of soy food intake with urinary estrogen levels in premenopausal women and in postmenopausal women have been inconsistent. We examined the associations of urinary isoflavone levels as well as soy food intake with estrone (E1) and estradiol (E2) in pre- and postmenopausal women. In addition, we compared the levels of isoflavones, E1 and E2 across current hormone users such as those receiving hormone replacement therapy and those using oral contraceptives and non-users among both pre- and postmenopausal women...
March 2019: Maturitas
Roberta Vaccaro, Daniele Zaccaria, Mauro Colombo, Simona Abbondanza, Antonio Guaita
OBJECTIVE: Hearing loss is a common chronic condition in elderly people. The prevalence of disabling hearing loss among the elderly worldwide is 33% and in Italy ranges from 0.6% (profound hearing loss) to 39% (mild hearing loss). We investigated the relationship between self-reported hearing disability and clinician-evaluated hearing status, and its longitudinal consequences in relation to cognitive impairment and functional decline. We hypothesised that subjects who report that they have a hearing disability have a worse functional and cognitive profile than people who do not report having a hearing disability...
March 2019: Maturitas
Jeanine M Van Ancum, Kimberley S van Schooten, Nini H Jonkman, Bas Huijben, Rob C van Lummel, Carel G M Meskers, Andrea B Maier, Mirjam Pijnappels
OBJECTIVES: Standardized tests of gait speed are regarded as being of clinical value, but they are typically performed under optimal conditions, and may not reflect daily-life gait behavior. The aim of this study was to compare 4-m gait speed to the distribution of daily-life gait speed. STUDY DESIGN: The cross-sectional Grey Power cohort included 254 community-dwelling participants aged 18 years or more. MAIN OUTCOME MEASURES: Pearson's correlations were used to compare gait speed assessed using a timed 4-m walk test at preferred pace, and daily-life gait speed obtained from tri-axial lower-back accelerometer data over seven consecutive days...
March 2019: Maturitas
Young-Mee Lim, Kyungah Jeong, Sa Ra Lee, Hye Won Chung, Wanhyung Lee
OBJECTIVE: We investigated whether, in the Korean population, the risk of premature ovarian insufficiency (POI) and early menopause varies with a woman's socioeconomic status, evaluated in relation to income, education, and occupation. METHODS: This cross-sectional, population-based study involved 31,508 women aged >19 years registered in the Korea National Health and Nutrition Examination Survey (KNHANES) (2007-2016). Menopausal status and socioeconomic status were obtained from self-reported KNHANES data...
March 2019: Maturitas
Marco Papageorgiou, Ali Raza, Sarah Fraser, Kulmira Nurgali, Vasso Apostolopoulos
The recreational use of methamphetamine (METH, or ice) is a global burden. It pervades and plagues contemporary society; it has been estimated that there are up to 35 million users worldwide. METH is a highly addictive psychotropic compound which acts on the central nervous system, and chronic use can induce psychotic behavior. METH has the capacity to modulate immune cells, giving the drug long-term effects which may manifest as neuropsychiatric disorders, and that increase susceptibility to communicable diseases, such as HIV...
March 2019: Maturitas
Guy I Sydney, Kalliopi J Ioakim, Stavroula A Paschou
An adrenal incidentaloma (AI) is an adrenal mass incidentally found via a radiological modality, independent of an endocrinological investigation. In this review, we aimed to investigate the possible reasons behind the increased frequency in AI detection, especially in ageing populations. The pathophysiological effects of insulin resistance (IR), hyperinsulinemia and various anabolic pathways are analyzed. In addition, we review data from studies indicating an increased incidence of adrenal adenomas and carcinomas in patients with type 2 diabetes mellitus (T2DM)...
March 2019: Maturitas
Claire Hardy, Amanda Griffiths, Myra S Hunter
OBJECTIVES: To develop and evaluate a 30-min online training for managers, in order to improve menopause-related knowledge, attitudes and confidence in having supportive discussions with women experiencing menopausal symptoms at work. The study also explored intentions and behaviour in terms of having conversations. STUDY DESIGN: A prospective, pre-post design involved collecting data at three time points: pre-training, immediately after training, and four weeks post-training...
February 2019: Maturitas
Hui Jeong An, Eun Hee Ahn, Jung Oh Kim, Han Sung Park, Chang Soo Ryu, Sung Hwan Cho, Ji Hyang Kim, Woo Sik Lee, Nam Keun Kim
BACKGROUND: Until now, an association between tissue inhibitor of metalloproteinase (TIMP) polymorphisms and primary ovarian insufficiency (POI) has not been identified. The aim of our study was to investigate whether the TIMP polymorphisms TIMP1T > C (rs4898), TIMP1G > A (rs6609533), TIMP2G > C (rs8179090), TIMP2G > A (rs2277698), TIMP3G > A (rs135029), and TIMP4T > C (rs3755724), which regulate matrix metalloproteinases (MMPs), confer a risk for primary ovarian insufficiency (POI) in Korean women (further studies would be required to evaluate the associations between TIMP polymorphisms and POI in other populations)...
February 2019: Maturitas
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