journal
https://read.qxmd.com/read/37733117/solid-pseudopapillary-neoplasms-of-the-pancreas-in-childhood-and-adolescence-an-analysis-of-the-german-registry-for-rare-pediatric-tumors-step
#1
JOURNAL ARTICLE
Christian Jentzsch, Jörg Fuchs, Abbas Agaimy, Christian Vokuhl, Gabriele Escherich, Claudia Blattmann, Steven W Warmann, Andreas Schmidt, Jürgen Schäfer, Ines B Brecht, Dominik T Schneider, Michael Abele
UNLABELLED: Solid pseudopapillary neoplasms (SPNs) are the most common entity among pediatric pancreatic tumors. Still, these are rare tumors with an annual incidence of 0.1-0.2/1,000,000, and little is known about their optimal treatment. This analysis aimed to increase knowledge about the occurrence and treatment strategies of SPN in childhood. Data regarding diagnostics, treatment, and outcome of children aged 0-18 years with SPN recorded in the German Registry for Rare Pediatric Tumors (STEP) were analyzed...
September 21, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37733116/continuing-difficulties-in-distinguishing-covid-19-mis-c-from-other-disease-entities
#2
LETTER
Nevio Cimolai
No abstract text is available yet for this article.
September 21, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37733115/standardized-treatment-and-diagnostic-approach-to-reduce-disease-burden-in-the-early-postoperative-phase-in-children-with-congenital-heart-defects-standard-study-a-pilot-randomized-controlled-trial
#3
JOURNAL ARTICLE
Antonia Vogt, Sascha Meyer, Hans-Joachim Schäfers, Julius Johannes Weise, Stefan Wagenpfeil, Hashim Abdul-Khaliq, Martin Poryo
To explore the effect of a daily goal checklist on pediatric cardiac intensive care unit (PCICU) length of stay (LOS) after congenital heart surgery. This study is a prospective randomized single-center study. Group characteristics were as follows: STANDARD group: n = 30, 36.7% female, median age 0.9 years; control group: n = 33, 36.4% female, median age 1.1 years. Invasive ventilation time, STAT categories, mean vasoactive-inotropic score (VIS)24h , maximal (max.) VIS24h , mean VIS24-48h , max...
September 21, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37733114/effect-of-intravenous-immunoglobulin-on-the-outcome-of-children-with-septic-shock-in-a-picu-a-retrospective-cohort-study
#4
JOURNAL ARTICLE
Haixin Huang, Jian Chen, Hongxing Dang, Chengjun Liu, Junming Huo, Yue-Qiang Fu
UNLABELLED: The therapeutic efficacy of intravenous immuneglobulin (IVIG) on children with septic shock remains uncertain. Therefore, we endeavored to investigate the impact of administering intravenous immunoglobulin (IVIG) in the pediatric intensive care unit (PICU) on patient with septic shock. We retrospectively analyzed the data of children admitted to the PICU due to septic shock from January 2017 to December 2021 in a tertiary pediatric hospital. The main outcome was in-hospital mortality...
September 21, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37728752/respiratory-syncytial-virus-can-we-still-believe-that-after-pandemic-bronchiolitis-is-not-a-critical-issue-for-public-health
#5
JOURNAL ARTICLE
Anna Chiara Vittucci, Livia Antilici, Cristina Russo, Anna Maria Caterina Musolino, Sebastian Cristaldi, Renato Cutrera, Sabrina Persia, Chiara Velia Di Maio, Massimiliano Raponi, Carlo Federico Perno, Alberto Villani
Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection among infants and young children, resulting in annual epidemics worldwide. Since the beginning of the COVID-19 pandemic, non-pharmacological interventions were applied, interfering with the circulation of most respiratory viruses, including RSV. The aim of this study is to analyze the RSV infection trend among hospitalized infants during the actual epidemic season (2022-2023) in comparison with the last pre-pandemic season (2018-2019), in order to outline whether significant differences emerge due to COVID-19 pandemia...
September 20, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37726566/effect-of-the-covid-19-pandemic-on-the-pediatric-infectious-disease-landscape
#6
REVIEW
Moshe Shmueli, Idan Lendner, Shalom Ben-Shimol
This narrative review aims to present an overview of the COVID-19 pandemic's effects on the landscape of pediatric infectious diseases. While COVID-19 generally results in mild symptoms and a favorable prognosis in children, the pandemic brought forth significant consequences. These included persistent symptoms among infected children ("long COVID"), a profound transformation in healthcare utilization (notably through the widespread adoption of telemedicine), and the implementation of optimization strategies within healthcare settings...
September 20, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37725211/unveiling-pseudo-pulseless-electrical-activity-pseudo-pea-in-ultrasound-integrated-infant-resuscitation
#7
JOURNAL ARTICLE
Belinda Chan, Susan Sieg, Yogen Singh
UNLABELLED: Point-of-care ultrasound (POCUS) holds immense potential to manage critically deteriorating infants within the neonatal intensive care unit (NICU) and is increasingly used in neonatal clinical practice worldwide. Recent ultrasound-based protocols such as the Sonographic Assessment of liFe-threatening Emergencies-Revised (SAFE-R) and Crashing Neonate Protocol (CNP) offer step-by-step guidance for diagnosing and addressing reversible causes of cardiorespiratory collapse. Traditionally, pulseless electrical activity (PEA) has been diagnosed solely based on absent pulses on clinical examination, disregarding myocardial activity...
September 19, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37725210/cystic-fibrosis-and-cftr-related-disorder-with-electrolyte-imbalance-at-diagnosis-clinical-features-and-outcome-in-an-italian-cohort
#8
JOURNAL ARTICLE
Vito Terlizzi, Rita Padoan, Giuseppina Leonetti, Pamela Vitullo, Antonella Tosco, Giovanni Taccetti, Cristina Fevola, Francesca Ficili, Angela Pepe, Piercarlo Poli, Laura Claut, Valeria Daccò, Donatello Salvatore
UNLABELLED: There is limited information available on the clinical data, sweat test trends, and outcomes of individuals with cystic fibrosis (CF) who present with an isolated episode of hypoelectrolytemia with metabolic alkalosis (HMA). This study describes a cohort of Italian individuals with HMA as presenting symptom. The study is a retrospective multicenter analysis of individuals who presented with HMA as an initial symptom and was followed at 8 Italian CF Centers, from March 1988 to March 2022...
September 19, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37723295/nomogram-to-predict-feeding-intolerance-in-critically-ill-children
#9
JOURNAL ARTICLE
Ying Lin, Xiaomin Wang, Lingyan Li, Yun Gou, Liping Zhang, Lijing Wang, Junhong Yang
Feed intolerance (FI) is significantly associated with poor prognosis in critically ill patients. This study aimed to understand the characteristics of children with FI and identify the factors predicting FI in critically ill children. This retrospective cohort study was conducted between January 2017 and June 2022 in the Pediatric Intensive Care Unit of a specialized children's hospital. Eighteen factors, including age, body mass index for age z-score (BAZ) < -2, paediatric index of mortality (PIM)3 score, Glasgow coma scale score, mechanical ventilation (MV), enteral nutrition delay, vasoactive drugs, sedatives, sepsis, heart disease, neurological disease, hypokalemia, arterial PH < 7...
September 19, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37721583/lung-ultrasound-in-neonates-with-congenital-diaphragmatic-hernia-and-the-need-for-a-quantitative-evaluation
#10
LETTER
Domenico Umberto De Rose, Chiara Maddaloni, Ludovica Martini, Sara Ronci, Irma Capolupo, Andrea Dotta, Flaminia Calzolari
No abstract text is available yet for this article.
September 18, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37721582/sleep-problems-at-ages-8-9-and-adhd-symptoms-at-ages-10-11-evidence-in-three-cohorts-from-inma-study
#11
JOURNAL ARTICLE
Llúcia González-Safont, Marisa Rebagliato, Ane Arregi, Paula Carrasco, Mònica Guxens, Oscar Vegas, Jordi Julvez, Marisa Estarlich
Sleep problems and attention deficit hyperactivity disorder (ADHD) are interrelated during childhood and preadolescence. The objective of this work is assessing if sleep problems at ages 8-9 represent an alarm sign for presenting ADHD problems at ages 10-11 in three cohorts from INMA Study. Participants were 1244 children from Gipuzkoa, Sabadell, and Valencia cohorts. Sleep problems were assessed (ages 8-9) with the sleep items of the Child's Behaviour Checklist (CBCL), and ADHD problems were collected through the Conner's Parent Rating Scales-Revised: Short Form (CPRS-R:S) (age 10-11)...
September 18, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37718387/pediatricians-confidence-level-in-diagnosing-and-treating-children-with-atopic-dermatitis-in-israel-based-on-a-self-efficacy-survey
#12
JOURNAL ARTICLE
Inbal Golan-Tripto, Atar Ben Shmuel, Liezl Muallem, Lior Yahav, Nicolas Andre, David Shaki, Amir Horev
Atopic dermatitis (AD) is one of childhood's most common skin conditions. Although pediatricians often diagnose and manage it, more than half refer even mild cases to dermatologists. In this study, we aimed to evaluate pediatric residents' and pediatricians' self-confidence regarding their ability to diagnose and manage AD. A cross-sectional questionnaire study was conducted with Israeli pediatric residents and pediatricians in 2022. The questionnaire was designed to distinguish participants with high vs...
September 18, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37715022/plasma-anti-myosin-autoantibodies-in-the-diagnosis-of-necrotizing-enterocolitis
#13
JOURNAL ARTICLE
Yuqiong Chen, Chaoting Lan, Weiyong Zhong, Kai Song, Zuyi Ma, Lihua Huang, Yun Zhu, Huimin Xia
UNLABELLED: We aimed to assess whether autoantibodies can be used as biomarkers for necrotizing enterocolitis (NEC) and applied for its early diagnosis. A prospective observational study was conducted in neonates with suspected NEC abdominal distension (the developmental study), which consisted of 50 neonates finally divided into NEC (n = 24) and non-NEC (n = 26) cohorts based on follow-up results. Serum samples were collected within 48 h of illness onset and used for screening NEC-associated plasma autoantibodies by autoantigen microarray...
September 16, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37707590/pediatric-multi-drug-resistant-tuberculosis-in-germany-diagnostic-and-therapeutic-challenges-of-an-orphan-disease
#14
JOURNAL ARTICLE
Hannah-Lena Schäfer, Michael Barker, Peter Follmann, Annette Günther, André Hörning, Petra Kaiser-Labusch, Sebastian Kerzel, Christoph Maier, Samra Roth, Christian Schmidt, Katharina Schütz, Florian Stehling, Marie Struffert, Nina Timmesfeld, Paul Vöhringer, Folke Brinkmann
UNLABELLED: Delay in diagnosing multidrug-resistant tuberculosis (MDR-pTB) in children prolongs time to effective treatment. Data on risk factors for pediatric MDR from low-incidence countries are scarce. Retrospective nationwide case-control study to analyze MDR-pTB cases in Germany between 2010 and 2020 in comparison to a drug-susceptible (DS)-pTB group. We included 52 MDR cases (24 tuberculosis (TB), 28 TB infection (TBI); mean age 7.3 years) and 56 DS cases (31 TB, 26 TBI; mean age 7...
September 14, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37707589/linear-growth-of-children-with-x-linked-hypophosphatemia-treated-with-burosumab-a-real-life-observational-study
#15
JOURNAL ARTICLE
Yael Levy-Shraga, Shelly Levi, Ravit Regev, Shoshana Gal, Avivit Brener, Yael Lebenthal, David Gillis, David Strich, Amnon Zung, Roxana Cleper, Yael Borovitz, Rachel Bello, Ariel Tenenbaum, Zvi Zadik, Miriam Davidovits, Leonid Zeitlin, Dov Tiosano
UNLABELLED: To assess the long-term efficacy of burosumab for pediatric patients with X-linked hypophosphatemia, focusing on linear growth. This multi-center retrospective study included 35 pediatric patients who began treatment with burosumab between January 2018 and January 2021. We collected clinical data, anthropometric measurements, laboratory results, and Rickets Severity Score (RSS), from 2 years prior to treatment initiation and up to 4 years after. Burosumab was initiated at a mean age of 7...
September 14, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37707588/prospective-assessment-of-early-developmental-markers-and-their-association-with-neuropsychological-impairment
#16
JOURNAL ARTICLE
Elisa Cainelli, Luca Vedovelli, Daniele Trevisanuto, Agnese Suppiej, Patrizia Bisiacchi
Children who experience adversities in the pre-perinatal period are at increased risk of developing impairment later in life, despite the absence of overt brain and neurological abnormalities. However, many of these children exhibit sequelae several years after a period of normal appearance. As a result, the need for reliable developmental assessments for the early detection of infants at high risk of adverse neurodevelopmental outcomes has emerged. The Griffiths Mental Developmental Scales have a promising but poorly explored prognostic ability...
September 14, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37702769/susceptibility-of-sars-cov2-infection-in-children
#17
REVIEW
Nicola Cotugno, Donato Amodio, Danilo Buonsenso, Paolo Palma
Coronavirus disease 2019 in children presents with distinct phenotype in comparison to adults. Overall, the pediatric infection with a generally milder clinical course of the acute infection compared to adults still faces several unknown aspects. Specifically, the presence of a wide range of inflammatory manifestations, including multisystem inflammatory syndrome in children (MIS-C), myocarditis, and long COVID in the period after infection suggests a particular susceptibility of some children upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection...
September 13, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37702768/advances-in-pediatric-cardiology
#18
EDITORIAL
Francesca Sperotto, José L López Guillén, Gregorio P Milani, Sebastiano A G Lava
No abstract text is available yet for this article.
September 13, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37698612/diagnostic-performance-of-artificial-intelligence-for-pediatric-pulmonary-nodule-detection-on-chest-computed-tomography-comparison-of-simulated-lower-radiation-doses
#19
JOURNAL ARTICLE
Rida Salman, HaiThuy N Nguyen, Andrew C Sher, Kristina Hallam, Victor J Seghers, Marla B K Sammer
UNLABELLED: The combination of low dose CT and AI performance in the pediatric population has not been explored. Understanding this relationship is relevant for pediatric patients given the potential radiation risks. Here, the objective was to determine the diagnostic performance of commercially available Computer Aided Detection (CAD) for pulmonary nodules in pediatric patients at simulated lower radiation doses. Retrospective chart review of 30 sequential patients between 12-18 years old who underwent a chest CT on the Siemens SOMATOM Force from December 20, 2021, to April 12, 2022...
September 12, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37695415/electrocardiographic-characteristics-of-newborns-with-ventricular-septal-defects-a-copenhagen-baby-heart-study
#20
JOURNAL ARTICLE
Christian Pihl, Maria Munk Pærregaard, Anne-Sophie Sillesen, Ruth Ottilia B Vøgg, Adrian Pietersen, Anna Axelsson Raja, Kasper Karmark Iversen, Henning Bundgaard, Alex Hørby Christensen
Ventricular septal defects (VSD) represent the most common congenital heart defect in newborns. We assessed the electrocardiographic characteristics of newborns with VSDs in a general population sample. The Copenhagen Baby Heart Study is a prospective population-based cohort study offering cardiac evaluation of newborns. Echocardiograms and electrocardiograms were obtained within 30 days after birth and systematically analysed. A VSD was identified in 530 newborns (mean age 11 ± 7 days, 42% boys)...
September 11, 2023: European Journal of Pediatrics
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