Chad C Carroll, Nathan W C Campbell, Rebecca L Lewis, Sarah E Preston, Chloe M Garrett, Hannah M Winstone, Anna C Barker, Johnny M Vanos, Lucas S Stouder, Camila Reyes, Matthew Fortino, Craig J Goergen, Zachary J Hass, Wayne W Campbell
BACKGROUND: While experimental research supports that resistance training (RT), especially with greater dietary protein intake, improves muscle mass and strength in older adults, comparable research on tendons is needed. OBJECTIVE: We assessed the effects of a protein-rich diet emphasizing lean beef, compared to two control diets, on RT-induced changes in skeletal muscle and tendon size and strength in older women. METHODS: We randomly assigned women [age: 66±1y, body mass index (BMI): 28±1 kg/m2 ] to groups that consumed 1) 0...
April 9, 2024: Journal of Nutrition
Rebecca L Brander, Chloe Puett, Elodie Becquey, Jef L Leroy, Marie T Ruel, Fidele Eric Sessou, Lieven Huybregts
BACKGROUND: Little is known about costs and cost-effectiveness of interventions that integrate wasting prevention into screening for child wasting. OBJECTIVE: This study's objective was to estimate the cost and cost-effectiveness of an intervention that integrated behavior change communication (BCC) and small-quantity lipid-based nutrient supplements (SQ-LNS) into platforms for wasting screening in Burkina Faso (a facility-based platform, where BCC was enhanced compared to standard care) and Mali (a community-based platform, with standard BCC)...
April 8, 2024: Journal of Nutrition
Rie Kishida, Kazumasa Yamagishi, Hiroyasu Iso, Junko Ishihara, Nobufumi Yasuda, Manami Inoue, Shoichiro Tsugane, Norie Sawada
BACKGROUND: Fruits and vegetables contain abundant amounts of antioxidant vitamins such as vitamin C, α-carotene, and β-carotene. Few prospective observational studies have investigated the effects of fruit and vegetable intake on the risk of dementia, and the results are inconsistent. OBJECTIVE: Our aim was to examine associations between fruit and vegetable intakes and the risk of disabling dementia. METHODS: We conducted a follow-up survey within the Japan Public Health Center-based Prospective Study involving 42,643 individuals aged 50 to 79 years at baseline (2000-2003)...
April 8, 2024: Journal of Nutrition
Fei Du, Linghui Tao
No abstract text is available yet for this article.
April 8, 2024: Journal of Nutrition
Caroline Buss, André Marette, Giselle S Escouto, Geneviève Pilon, Cristiane V Tovo
No abstract text is available yet for this article.
April 8, 2024: Journal of Nutrition
Frédéric Baudron, Jill E Cairns, Stephan M Haefele, Kirsty L Hassall, Thokozile Ndhlela, Isaiah Nyagumbo, Muneta G Manzeke-Kangara, Edward J M Joy
BACKGROUND: Evidence of the effectiveness of biofortified maize with higher pro-vitamin A (PVA) to address vitamin A deficiency in rural Africa remains scant. OBJECTIVES: This study projects the impact of adopting PVA maize for a diversity of households in an area typical of rural Zimbabwe, and models the cost and composition of diets adequate in vitamin A. METHODS: Household-level weighed food records were generated from 30 rural households during a week in April and November 2021...
April 8, 2024: Journal of Nutrition
Huixin Xue, Rui Qin, Qi Xi, Shuxin Xiao, Yiyuan Chen, Yuxin Liu, Bo Xu, Xiumei Han, Hong Lv, Haiting Hu, Lingmin Hu, Tao Jiang, Yangqian Jiang, Ye Ding, Jiangbo Du, Hongxia Ma, Yuan Lin, Zhibin Hu
BACKGROUND: Cholesterol plays a vital role in fetal growth and development during pregnancy. There remains controversial over whether pregnant women should limit their cholesterol intake. OBJECTIVES: To investigate the association between maternal dietary cholesterol intake during pregnancy and infant birth weight in a Chinese prospective cohort study. METHODS: A total of 4,146 mother-child pairs were included based on the Jiangsu Birth Cohort (JBC) study...
April 8, 2024: Journal of Nutrition
Kamrul Zaman, Hee-Chang Mun, Samantha M Solon-Biet, Alistair M Senior, David Raubenheimer, Stephen J Simpson, Arthur D Conigrave
BACKGROUND: A balanced intake of protein and constituent amino acids (AAs) requires adjustments to total food intake (protein leverage; PL); and (ii) food selection to balance deficits and excesses (complementary feeding). We provided mice with choices of Casein and Whey, two protein sources that are complementary in AA balance, across a range of protein concentrations (P%) of digestible energy (DE). OBJECTIVES: We determined whether: PL operates similarly for Casein and Whey; one protein source is preferred at control P%; the preference changes as P% falls; and whether AA intakes under control and low P% levels identify AAs that drive changes in protein selection...
April 5, 2024: Journal of Nutrition
Hope A Weiler, Agnieszka Bielecki, Wen Fu, Isabelle Demonty, Stephen P J Brooks
BACKGROUND: Matrix effects are a known problem with immunoassays measuring serum 25-hydroxyvitamin D (25(OH)D). OBJECTIVE: To determine if the inverse association between serum 25(OH)D and serum cholesterol concentrations is a function of assay method: Diasorin Liaison 25(OH) Vitamin D Total Assay (Liaison Total Assay), an immunoassay, vs. liquid chromatography tandem mass spectrometry (LC-MS/MS). METHODS: /Design: Canadian Health Measures Survey data and biobank serum (white males 20-79 years, n=392) were evaluated for bias in serum 25(OH)D using Bland-Altman plots...
April 4, 2024: Journal of Nutrition
Tianna Rusnak, Jessy Azarcoya-Barrera, Alexander Makarowski, René L Jacobs, Caroline Richard
BACKGROUND: Phosphatidylcholine (PC) derived from eggs has been shown to beneficially modulate T cell response and intestinal permeability under the context of a high-fat diet. OBJECTIVES: The objective of this study was to determine whether there is a differential effect of plant and animal-derived sources of PC on immune function. METHODS: Four-week-old male Wistar rats were randomized to consume one of 4 diets (n=10/group) for 12 weeks, all containing 1...
April 4, 2024: Journal of Nutrition
Lynnette M Neufeld, Stella Nordhagen, Jef L Leroy, Noora-Lisa Aberman, Inka Barnett, Eric Djimeu Wouabe, Amy Webb Girard, Wendy Gonzalez, Carol E Levin, Mduduzi N N Mbuya, Eduardo Nakasone, Christina Nyhus Dhillon, Dave Prescott, Matt Smith, David Tschirley
While there is growing global momentum behind food systems strategies to improve planetary and human health-including nutrition-there is limited evidence of what types of food systems interventions work. Evaluating these types of interventions is challenging due to their complex and dynamic nature and lack of fit with standard evaluation methods. In this paper, we draw on a portfolio of six evaluations of food systems interventions in Africa and South Asia that were intended to improve nutrition. We identify key methodological challenges and formulate recommendations to improve the quality of such studies...
April 4, 2024: Journal of Nutrition
Edward Ross Pennington, Rafia Virk, Meagan D Bridges, Brooke E Bathon, Nari Beatty, Rosemary S Gray, Patrick Kelley, Stephen R Wassall, Jonathan Manke, Michael Armstrong, Nichole Reisdorph, Rachel Vanduinen, Jenifer I Fenton, Kymberly M Gowdy, Saame Raza Shaikh
BACKGROUND: Docosahexaenoic acid (DHA) controls the biophysical organization of plasma membrane sphingolipid/cholesterol-enriched lipid rafts to exert anti-inflammatory effects, particularly in lymphocytes. However, the impact of DHA on the spatial arrangement of alveolar macrophage lipid rafts and inflammation is unknown. OBJECTIVE: The primary objective was to determine how DHA controls lipid raft organization and function of alveolar macrophages. As proof-of-concept, we also investigated DHA's anti-inflammatory effects on select pulmonary inflammatory markers with a murine influenza model...
April 4, 2024: Journal of Nutrition
Laura S Hackl, Crystal D Karakochuk, Dora Inés Mazariegos, Kidola Jeremiah, Omar Obeid, Nirmal Ravi, Desalegn A Ayana, Veronica Varela, Silvia Alayón, Omar Dary, Denish Moorthy
BACKGROUND: Anemia prevalence estimates reported in population surveys can vary based on the blood-specimen source (capillary or venous) and analytical device (haematology auto-analyzers or portable hemoglobinometers) used for hemoglobin (Hb) determination. METHODS: This multi-site (Cambodia, Ethiopia, Guatemala, Lebanon, Nigeria, Tanzania) study assessed Hb measurements in paired venous and capillary blood-specimen from apparently healthy women (15-49 years) and children (12-59 months) using three HemoCue® Hb models (201+, 301, 801)...
April 3, 2024: Journal of Nutrition
Hope A Weiler, Huma Rana, Jennifer McCrea, Lidia Loukine, Yvette Bonvalot, Loan Nguyen, Kathryn Hopperton, Marcia Cooper, Jesse Bertinato, Kelsey Vercammen, Wei Luo, Leanne Dunstan, Carley Nicholson, Jane Yuan, Shawn Brule
BACKGROUND: In Canada, nutrition policy, as outlined in the Nutrition for Healthy Term Infants recommendations, includes a daily vitamin D supplement of 10 μg (400 IU) for breastfed infants and young children to support adequate vitamin D status. OBJECTIVES: This study aimed to report on adherence to vitamin D supplementation recommendations for breastfed infants (≤12 months); and for children breastfed >12 mo. METHODS: Canadian Community Health Survey (paired-cycles 2015/2016 and 2017/2018) maternal experiences data for infants born 2012-2018 who received any breastmilk formed the sample (n = 7079)...
March 26, 2024: Journal of Nutrition
Mahesha U Asiriwardhana, O Chandani Dinesh, Janet A Brunton, Robert F Bertolo
BACKGROUND: Creatine plays a significant role in energy metabolism and positively impacts anaerobic energy capacity, muscle mass, and physical performance. Endogenous creatine synthesis requires guanidinoacetic acid (GAA) and methionine. GAA can be an alternative to creatine supplements and has been tested as a beneficial feed additive in the animal industry. When pigs are fed GAA with excess methionine, creatine is synthesized without feedback regulation. In contrast, when dietary methionine is limiting, creatine synthesis is limited, yet GAA does not accumulate in plasma, urine, or liver...
March 23, 2024: Journal of Nutrition
Mary R Dicklin, Joshua C Anthony, Barbara L Winters, Kevin C Maki
There is an increasing body of evidence supporting a link between low intakes of omega-3 long chain polyunsaturated fatty acids (LCPUFA) and numerous diseases and health conditions. However, few people are achieving the levels of fish/seafood or eicosapentaenoic acid and docosahexaenoic acid intake recommended in national and international guidelines. Knowledge of a person's omega-3 LCPUFA status will benefit the interpretation of research results and could be expected to lead to an increased effort to increase intake...
March 22, 2024: Journal of Nutrition
Levi Elms, Brittany Hand, Monika Skubisz, Karen P Best, Luke E Grzeskowiak, Geraint B Rogers, Tim J Green, Steven L Taylor
BACKGROUND: Iron deficiency is the most common nutritional deficiency worldwide, particularly for young children and women of reproductive age. While oral iron supplements are routinely recommended and generally considered safe, iron supplementation has been shown to alter the fecal microbiota in low-income countries. Little is known about the effect of iron supplementation on the fecal microbiota in high-income settings. OBJECTIVE: To assess the effect of oral iron supplementation versus placebo on the gut microbiome in non-pregnant women of reproductive age in a high-income country...
March 21, 2024: Journal of Nutrition
Insaf Loukil, Ester Cisneros Aguilera, Annick Vachon, Pauline Léveillé, Mélanie Plourde
UNLABELLED: The brain is concentrated in omega-3 fatty acids (ω3 FAs) and these FAs must come from the plasma pool. The two main ω3 FAs, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), must be non esterified (NEFA) or esterified in phospholipid (PL) to reach the brain. We hypothesized that the plasma levels of these ω3 FAs can be modulated by sex, body mass index (BMI), age, and the presence of the apolipoprotein E epsilon 4 allele (APOE4) in response to the supplementation...
March 19, 2024: Journal of Nutrition
Jazmin Castañeda, Enrique Almanza-Aguilera, Adriana Monge, Susana Lozano-Esparza, Juan Eugenio Hernández-Ávila, Martin Lajous, Raul Zamora-Ros
BACKGROUND: Observational studies have reported that total (poly)phenol intake is associated with a reduction in all-cause and cardiovascular mortality, but mainly from high-income countries, where (poly)phenol intake may differ from low- and middle-income countries. OBJECTIVE: Our objective was to evaluate the association between the intake of total, all classes and subclasses of (poly)phenols and the risk of all-cause and cause-specific mortality in a Mexican cohort...
March 13, 2024: Journal of Nutrition
Qingying Tian, Lin Li, Zhilei Shan, Qi Lu, Rui Li, Sen Liu, Xiaoyu Lin, Ruyi Li, Xue Chen, Yunjing Ou, An Pan, Gang Liu
BACKGROUND: Although low-carbohydrate and low-fat diets have been shown to have short-term metabolic benefits, the associations of these dietary patterns, particularly different food sources and macronutrient quality, with mortality in people with cardiovascular disease (CVD) remain unclear. OBJECTIVES: To examine the associations of different types of lower-carbohydrate diets (LCDs) and lower-fat diets (LFDs) with mortality among individuals with CVD. METHODS: This study included 3971 adults with CVD from the NHANES 1999-2014...
March 13, 2024: Journal of Nutrition
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