journal
https://read.qxmd.com/read/37706372/prognostic-significance-of-prolonged-corrected-qt-interval-in-cerebral-contusion
#1
JOURNAL ARTICLE
Ahmed Yasin Yavuz, Ozan Baskurt, Yunus Kurtulus, Idris Avci
BACKGROUND & OBJECTIVES: Cerebral contusion (CC) results in a release of catecholamines, autonomic dysfunction and neural stimulation that can lead to a number of cardiac adverse events, so it is critical to determine these. So the objective of this study was to investigate the prognostic significance of electrocardiographic changes, particularly the effects of a prolonged corrected QT (QTc) interval in CC. METHODS: In this retrospective cohort study, 110 patients with CC were evaluated...
September 14, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37706371/book-review
#2
JOURNAL ARTICLE
Atul Prabhakar Kulkarni
No abstract text is available yet for this article.
September 14, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37706370/association-of-cyp3a5-3-cyp3a4-18-cyp2b6-6-polymorphisms-with-imatinib-treatment-outcome-in-azerbaijani-chronic-myeloid-leukaemia-patients
#3
JOURNAL ARTICLE
Chingiz Asadov, Nigar Karimova, Aypara Hasanova, Bayram Bayramov, Aytan Shirinova, Zohra Alimirzoyeva
BACKGROUND & OBJECTIVES: Imatinib mesylate (IM) is a reliable first line treatment for chronic myeloid leukaemia (CML). Nevertheless, despite promising results, a considerable proportion of patients develop resistance to the drug. Cytochrome P450 (CYP) enzymes play a crucial role in IM metabolism. Thus, point mutations in CYP genes may modify IM enzyme activity resulting in insufficient treatment response. This investigation was aimed to identify the functional impact of CYP3A5*3, CYP3A4*18 and CYP2B6*6 polymorphisms on the IM response in patients with CML in Azerbaijan...
September 14, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37675692/correlation-of-cyp2r1-gene-promoter-methylation-with-circulating-vitamin-d-levels-among-healthy-adults
#4
JOURNAL ARTICLE
Ashvin Varadharajan, M K Sibin, S V Athira, Arijit Kumar Ghosh, Pratibha Misra
BACKGROUND & OBJECTIVES: Despite being a tropical country, vitamin D deficiency is highly prevalent in India with studies indicating 40-99 per cent prevalence. Apart from calcium and phosphate metabolism, vitamin D is involved in cell cycle regulation, cardiovascular, hepatoprotection. The metabolism of vitamin D is regulated by vitamin D tool genes (CYP2R1/CYP27B1/CYP24A1/VDR). The promoter regions of some of these genes have CpG islands, making them prone to methylation induced gene silencing, which may cause a reduction in circulating vitamin D levels...
September 6, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37675691/spatio-temporal-distribution-seasonality-of-highly-pathogenic-avian-influenza-h5n1-h5n8-outbreaks-in-india-2006-2021
#5
JOURNAL ARTICLE
Shailesh D Pawar, Sadhana S Kode, Sachin S Keng, Deeksha S Tare, Satish A Pande
BACKGROUND & OBJECTIVES: The highly pathogenic avian influenza (HPAI) H5N1 and H5N8 viruses have been one of the leading causes of avian diseases worldwide, resulting in severe economic losses and posing potential zoonotic risk. There are no reports on the correlation of the seasonality of H5N1 and H5N8 viruses with the migratory bird season in India, along with the species affected. The present report describes the distribution and seasonality of HPAI outbreaks in India from 2006 to 2021...
September 6, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37675690/authors-response
#6
LETTER
Jatin Sharma, C S Gautam, Harmanjit Singh, Jagjit Singh
No abstract text is available yet for this article.
September 6, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37675689/determinants-of-post-discharge-mortality-among-hospitalized-covid-19-patients-nested-matched-case-control-analyses-from-the-national-clinical-registry-for-covid-19
#7
JOURNAL ARTICLE
Gunjan Kumar, Arunansu Talukdar, Alka Turuk, Ashish Bhalla, Subhasis Mukherjee, Pankaj Bhardwaj, Tarun Bhatnagar, Aparna Mukherjee
BACKGROUND & OBJECTIVES: : The post-acute effects of COVID-19 are continually being updated. This investigation was conducted to evaluate the determinants of post discharge mortality in hospitalized COVID-19 patients, especially 18-45 yr of age. METHODS: : A series of three nested case-control analyses was conducted on follow up data collected in the National Clinical Registry for COVID-19 between September 2020 and February 2023 from 31 hospitals. Matching (1:4) was done by the date of hospital admission ±14 days for the following comparisons: (i) case-patients reported as dead vs...
September 6, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37675688/tafenoquine-for-the-radical-cure-versus-prophylaxis-of-plasmodium-vivax-malaria-the-importance-of-using-the-appropriate-data-set
#8
LETTER
Raman Sharma, Chao Chen, Ioana-Gabriela Fiţa, Rachel A Gibson, Siôn Jones, Anup Pingle, Katie Rolfe, Hema Sharma, Panayota Bird
No abstract text is available yet for this article.
September 6, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37675687/eco-epidemiology-triad-to-explain-infectious-diseases
#9
JOURNAL ARTICLE
T Jacob John, Rajeev Zachariah Kompithra
No abstract text is available yet for this article.
September 6, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37675686/biofilm-profile-of-candidaemia-isolates
#10
JOURNAL ARTICLE
M S Sheena, Rakesh Singh
No abstract text is available yet for this article.
September 6, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37675685/evidence-based-traditional-medicine-for-transforming-global-health-wellbeing
#11
EDITORIAL
Bhushan Patwardhan, L Susan Wieland, Obijiofor Aginam, Anchalee Chuthaputti, Ricardo Ghelman, Roshanak Ghods, Goh Cheng Soon, Motlalepula G Matsabisa, Georg Seifert, Sione Tu'itahi, Kim Sung Chol, Shyama Kuruvilla, Kathi Kemper, Holger Cramer, H R Nagendra, Anup Thakar, Tanuja Nesari, Sanjeev Sharma, Narayanam Srikanth, Rabinarayan Acharya
No abstract text is available yet for this article.
September 6, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37555406/-brca1-promoter-methylation-its-immunohistochemical-correlation-in-sporadic-breast-cancer
#12
JOURNAL ARTICLE
Fatima Khan, Preeti Agarwal, Sameer Gupta, Malti Kumari Maurya, Pooja Singh, Apoorva Agarwal, Kulranjan Singh, Abhinav Arun Sonkar, Madhu Mati Goel
BACKGROUND & OBJECTIVES: : Studies have shown that apart from hereditary breast carcinomas, breast cancer susceptibility gene 1 (BRCA1) mutations conferring to its loss are seen in sporadic breast carcinomas (SBC) as well. The aim of the present study was to assess BRCA1 methylation in females presenting at King George's Medical University, Lucknow, with SBC by both immunohistochemistry (IHC) and methylation PCR with respect to hormonal profile and various morphological prognostic parameters...
August 9, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37555405/a-multicentric-qualitative-analysis-of-district-level-challenges-faced-by-frontline-health-managers-during-the-implementation-of-covid-19-related-policies-during-the-pandemic-in-india
#13
JOURNAL ARTICLE
Rashmi Kundapur, Sumit Aggarwal, Rakhal Gaitonde, Anusha Rashmi, Leyanna Susan George, Arvind Pandey, Yogita Bavaskar
INTERPRETATION & CONCLUSIONS: The COVID-19 guidelines provided by the Centre were found to be useful at district levels. However, there was a need to make some operational and administrative modifications in order to implement these guidelines locally and to ensure their acceptability. RESULTS: Challenges faced in implementing quarantine rules were numerous, and it was also compounded by stigma attached with the disease. The need for adapting the guidelines as per local considerations, inclusion of components of financial management at local level, management of tribal and vulnerable populations and migrants in COVID context were strongly suggested...
August 9, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37555404/early-phase-clinical-trials-in-india-need-scope
#14
JOURNAL ARTICLE
Nilima Arun Kshirsagar, Monika Pahuja, N S Chatterjee, V P Kamboj
No abstract text is available yet for this article.
August 9, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37555403/methylation-of-brca1-promoter-in-sporadic-breast-cancer
#15
JOURNAL ARTICLE
Sunil Vitthalrao Jagtap, Swati S Jagtap
No abstract text is available yet for this article.
August 9, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37555402/book-review
#16
JOURNAL ARTICLE
A B Dey
No abstract text is available yet for this article.
August 9, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37555401/clinical-spectrum-changing-presentation-of-celiac-disease-in-a-large-cohort-of-indian-children-experience-from-a-tertiary-care-referral-centre
#17
JOURNAL ARTICLE
Sadhna Bhasin Lal, Vybhav Venkatesh, Aradhana Aneja, Keerthivasan Seetharaman, Yashwant Kumar, Kaushal Kishor Prasad, Surinder Singh Rana
BACKGROUND & OBJECTIVES: : Celiac disease (CD) is a genetic immune mediated disorder characterised by gluten intolerance. This single centre study, from north India was aimed to assess the clinical, serological and histological profile of CD in a large cohort of children and the changing trends in its presentation. METHODS: : A review of clinical details of CD children diagnosed between 2000 and 2019 and currently on follow up was performed. Information on demography, symptoms, associated conditions, serology, biopsy findings and gluten-free diet were analyzed...
August 9, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37530233/sars-cov-2-antigen-detection-in-deceased-bodies-implications-for-infection-prevention
#18
JOURNAL ARTICLE
Meenakshi Sharma, Vandana Vijayeta Kiro, Sharad Srivastav, Nasim Mansoori, Parin Lalwani, Amit Lathwal, Richa Agrawal, Kapil Dev Soni, Nirupam Madaan, Rajesh Malhotra, Anjan Trikha, Sanjeev Lalwani, Purva Mathur
BACKGROUND & OBJECTIVES: High transmissibility of the SARS-CoV-2 has significant implications on healthcare workers' safety, preservation, handling, transportation and disposal of the deceased bodies. The objective of this study was to detect SARS-CoV-2 antigen in nasopharyngeal samples and its implications in handling and care of COVID-19 deceased bodies. METHODS: A study was conducted at a dedicated COVID-19 centre on deceased individuals from April to December 2020...
August 2, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37530231/malignant-gastric-calcification-an-enigmatic-entity
#19
JOURNAL ARTICLE
Suvendu Maji, Jayesh Kumar Jha
No abstract text is available yet for this article.
August 2, 2023: Indian Journal of Medical Research
https://read.qxmd.com/read/37530230/role-of-calcium-or-vitamin-d-supplementation-in-preventing-osteoporotic-fracture-in-the-elderly-a-systematic-review-meta-analysis
#20
JOURNAL ARTICLE
Kavin Khatri, Manmeet Kaur, Tanish Dhir, Ankita Kankaria, Hobinder Arora
BACKGROUND & OBJECTIVES: Calcium and vitamin D, separately or in combination are usually prescribed to prevent fragility fractures in elderly population. However, there are conflicting results regarding the ideal dosage and overall efficacy obtained from randomized controlled trials conducted in the past. The objective is to assess the fracture risk with the administration of calcium or vitamin D alone or in combination in elderly population (>60 yr). METHODS: PubMed, Cochrane and Embase databases were searched to identify the studies from inception to February 2021 with keywords, 'vitamin D', 'calcium' and 'fracture' to identify randomized controlled trials...
August 2, 2023: Indian Journal of Medical Research
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