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Indian Heart Journal

Ahmed Mohamed Abuosa, Ayman Hassan Elshiekh, Kahekashan Qureshi, Mohammed Burhan Abrar, Mona A Kholeif, Abdulhalim Jamal Kinsara, Abdulwahab Andejani, Adel H Ahmed, John G F Cleland
OBJECTIVE: Deterioration in ventricular function is often observed in patients treated with anthracyclines for cancer. There is a paucity of evidence on interventions that might provide cardio-protection. We investigated whether prophylactic use of carvedilol can prevent doxorubicin-induced cardiotoxicity and whether any observed effect is dose related. METHODS: A prospective, randomized, double-blind study in patients treated with doxorubicin, comparing placebo (n = 38) with different doses of carvedilol [6...
December 2018: Indian Heart Journal
Bishav Mohan, Rohit Tandon, Raahat Bansal, Maninder Singh, Bhupinder Singh, Abhishek Goyal, Shibba Takkar Chhabra, Naved Aslam, Gurpreet S Wander
INTRODUCTION: There is limited data regarding in hospital determinants of clinical deterioration and outcome in sub massive pulmonary embolism (PE). We aimed to evaluate these determinants by comparing biomarkers, CT pulmonary angiogram echocardiography, electrocardiography variables. METHODS: 57 patients of sub massive PE diagnosed on CT pulmonary angiogram were included. All patients received UFH on admission and were divided into two groups based on their clinical course...
December 2018: Indian Heart Journal
Shalini Verma, Pooja Bhati, Irshad Ahmad, Sidra Masroor, Kamran Ali, Deepika Singla, Mohammed Ejaz Hussain
BACKGROUND: Cardiac autonomic neuropathy (CAN) is a commonly overlooked complication of Type 2 Diabetes Mellitus (T2DM) characterized by imbalance between sympathetic and parasympathetic supply to the heart. The susceptibility of heart to dysrhythmias and fatal events increases during and after exercise due to a shift in autonomic regulation. Diabetes and hypertension (HTN) frequently occur concurrently and both conditions lead to impaired cardiac autonomic control. However, their impact together on post-exercise autonomic recovery remains to be explored...
December 2018: Indian Heart Journal
Deepak Agrawal, S C Manchanda, J P S Sawhney, Bhuwanesh Kandpal, Rajneesh Jain, Ashwani Mehta, Arun Mohanty, Rajiv Passey, Aman Makhija, Manish Kr Sharma
OBJECTIVE: Primary objective was to compare the effects of atorvastatin 40mg vs 80mg on LDL-C in Indian patients with atherosclerotic dyslipidemia. Secondary objectives were to compare the effects of atorvastatin 40mg vs 80mg on HDL-C and triglycerides and also comparing of side effects (myopathy, hepatotoxicity and new onset diabetes mellitus) of both doses. METHOD: This Study is A Prospective, randomized, open-label, comparative study. This study was conducted on 240 patients of dyslipidemia (as per ACC/AHA 2013 lipid guidelines) attending the OPD/wards/CCU of department of cardiology, Sir Ganga Ram Hospital...
December 2018: Indian Heart Journal
Prakash Chand Negi, Rajeev Merwaha, Shivani Rao, Sanjeev Asotra, Anjali Mahajan, Ashish Joshi
BACKGROUND: The lack of surveillance system is a major barrier in prevention and control of rheumatic fever/rheumatic heart disease (RF/RHD). Efficacy of school-based surveillance was evaluated for detection of acute pharyngitis and RF/RHD in Shimla district, HP. METHODS: The schools in district Shimla were randomly assigned to intervention and controlled arm (442 vs. 441 schools). The trained nodal teachers reported children with symptoms of acute pharyngitis and or RF/RHD in intervention arm and children taken to hospitals by parents for symptoms of acute pharyngitis and or RF/RHD under control arm through mobile phone to coordinating centre...
December 2018: Indian Heart Journal
P C Negi, Sachin Sondhi, Vivek Rana, Sanjay Rathoure, Ravi Kumar, Nirmal Kolte, Ritesh Kumar, Shivani Rao, Ashish Diman, Kunal Mahajan, Munish Dev, Arvind Kandoria, Neeraj Ganju, Rajeev Bhardwaj, Rajeev Merwaha, Rajesh Sharma, Sanjeev Asotra
OBJECTIVE: To report the prevalence, risk factors and consequences of atrial fibrillation (AF) in patients of rheumatic heart disease (RHD). METHODS: The Himachal Pradesh- Rheumatic Fever/Rheumatic Heart Disease (HP-RF/RHD) Registry database of 1918 patients was analyzed. AF was diagnosed with 12-lead ECG recording at entry in to the registry. The association of AF with nature and severity of valvular dysfunction was analyzed, adjusted for age, left atrial (LA) dimension and pulmonary arterial hypertension using multivariable logistic regression model and strength of association was reported as odds ratio (OR) with 95% confidence intervals (C...
December 2018: Indian Heart Journal
Manoj Kumar, Harmeet Singh Rehan, Raman Puri, Madhur Yadav, Lalit Kumar Gupta
OBJECTIVE: Data regarding efficacy comparison of daily regimen (DR) versus every other day regimen (EODR) atorvastatin therapy is not validated by estimation of serum hydroxymethylglutaryl-CoA reductase (HMGCR) levels and HMGCR correlation with lipid indices. METHODS: In this randomized controlled trial, we compared the efficacy of DR versus EODR by measuring lipid indices and serum HMGCR levels at baseline and after 12 weeks of 10 mg atorvastatin therapy. Primary endpoint was comparison of mean change in serum HMGCR levels and lipid indices of both groups and their correlation with each other...
December 2018: Indian Heart Journal
Azin Alizadehasl, Mohammad Ali Akbarzadeh, Anita Sadeghpour, Majid Haghjoo, Behshid Ghadrdoost, Mahbubeh Zeighami, Arezoo Haghighat Talab
BACKGROUND: According to American Heart Association guidelines, QRS duration and morphology are used to select patients for cardiac resynchronization therapy (CRT). But still there are some patients who are not responding to this device. We investigated whether the Cardiogoniometry (CGM) as a three-dimensional vectorcardiogram method can improve patient selection. METHODS: Echocardiography and CGM were performed for 25 consecutive patients with Left bundle branch morphology who were candidate for CRT implantation and were in sinus rhythm...
December 2018: Indian Heart Journal
Mohammad M Al-Daydamony, Ahmad Shawky, Ahmad Tharwat
BACKGROUND: Coronary artery disease (CAD) is a leading cause of morbidity and death. Early diagnosis of patients with left main and/or three-vessel disease (LM/3VD) among acute coronary syndrome (ACS) patients is beneficial. The relation between erectile dysfunction (ED) and cardiovascular diseases was previously noticed. The aim of our work was to find out if the severity of ED could predict the presence of LM/3VD in ACS patients. PATIENTS AND METHODS: Eighty-five male patients with ACS were included in the study...
December 2018: Indian Heart Journal
Kenan Yalta
No abstract text is available yet for this article.
December 2018: Indian Heart Journal
Narendra Kumar Arya, Kamlesh Singh, Anushree Malik, Rahul Mehrotra
BACKGROUND: Meditation has been a key component of eastern spiritual practices. Heartfulness meditation is a unique heart based system with key practices like cleaning and meditation aided by yogic transmission. OBJECTIVE: To study the effects of Heartfulness cleaning and meditation (guided by Heartfulness trainer) on heart rate variability (HRV), blood pressure (BP) and heart rate (HR). METHODS: A total of 30 participants (21 males, 9 females; age range 19-70 years, M = 45...
December 2018: Indian Heart Journal
Sercan Okutucu, Mehmet Kadri Akboga, Ali Oto
No abstract text is available yet for this article.
December 2018: Indian Heart Journal
Rajkumar Doshi, Krunalkumar Patel, Pranavi Patel, Perwaiz M Meraj
No abstract text is available yet for this article.
December 2018: Indian Heart Journal
Nandhakumar Vasu, Vijayakumar Subban, S Ajit Mullasari
Percutaneous coronary intervention (PCI) is often denied for individuals with coronary artery disease who are prone to develop contrast-induced acute kidney injury. We report a 73-year-old, stage 3 chronic kidney disease patient (CKD), who underwent coronary artery bypass surgery and saphenous vein graft (SVG) stenting in the past, presented with in-stent restenosis (ISR) of SVG stent. Zero contrast optical coherence tomography (OCT) guided-PCI was successfully performed using low molecular weight dextran-40 (LMWD-40) as the flush medium...
December 2018: Indian Heart Journal
Pradeep Vaideeswar, Saranya Singaravel, Prajakta Gupte
Thyroid dysfunctions, particularly hypothyroidism, predispose to cardiovascular diseases, such as atherosclerotic coronary artery disease. However, thyroid functions are not always assessed in such patients. In this report, we studied the cases with pathologically evident ischemic heart disease (IHD) at autopsy and correlated with the absence or presence of thyroid disease. In a 5-year retrospective autopsy-based study, cases with IHD in whom the thyroid gland was dissected at autopsy were analyzed. The thyroid gland was available for assessment in 181 of the 255 autopsied cases with IHD...
December 2018: Indian Heart Journal
Nandhakumar Vasu, Latchumanadhas Kalidoss, Ezhilan Janakiraman, Vijayakumar Subban, Mullasari S Ajit
Patent hemostasis technique is used with the trans radial (TR) band to prevent radial artery occlusion following diagnostic coronary angiogram or percutaneous coronary intervention using radial artery access. We report epidermal bulla as a complication of TR band usage and a modified patent hemostasis technique using barbeau test to prevent this complication.
December 2018: Indian Heart Journal
Aniruddha Vyas, Yash Lokhandwala
Use of atrial pacing has been known, yet underutilized tool for effective temporary pacing whenever needed early after cardiac surgery. The reasons may be frequent failures of epicardial wires (fixed over atria intra-operative) leading to loss of capture. Endocardial atrial pacing sites for temporary pacing are unstable and hence continuous pacing with acceptable thresholds is impossible. We describe a case of ischemic cardiomyopathy and severe left ventricle systolic dysfunction who required atrial pacing post coronary artery bypass grafting (CABG) surgery for around 48-72 hours starting 4th day post operation when he had multiple episodes of ventricular fibrillation (VF) needing many defibrillation shocks...
December 2018: Indian Heart Journal
Aparna A Bhanushali, Gayatri Pradhan, A Contractor, Bibhu R Das
Genome wide association study has identified rs7025486 G>A polymorphism within DAB2IP (Disabled homolog 2-interacting protein) gene with increased risk of coronary heart disease (CAD). In this study we have determined the frequency and association of rs7025486 with CAD in Indians. The study was performed on 214 patients with CAD and 125 controls. The 'AA' genotype was associated with an increased risk in the CAD age group <50 yrs as compared to CAD age group>50 yrs (OR 3.149; P 0.034) and controls >50 yrs (OR 3...
December 2018: Indian Heart Journal
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