journal
MENU ▼
Read by QxMD icon Read
search

European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes

journal
https://read.qxmd.com/read/30799407/intraoperative-sentinel-node-mapping-in-the-colon-potential-and-pitfalls
#1
Andrew C Currie
Sentinel lymph node mapping (SLNM) may play a significant role in future delivery of colon cancer surgery because of an increase in early-stage, node-negative disease due to national bowel cancer screening programmes. Traditionally, colon lymphatic drainage has not been thought relevant as the operative approach cannot be tailored. Recent advances in local and endoscopic risk-reducing interventions for colonic malignancy have caused a rethink in approach. SLNM was initially attempted with blue dye techniques with limited success...
February 22, 2019: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30759434/kinetics-of-hepatic-volume-evolution-and-architectural-changes-after-major-resection-in-a-porcine-model
#2
Mohamed Bekheit, Petru O Bucur, Chloe Audebert, Elodie Miquelestorena-Standley, Irene Vignon-Clementel, Eric Vibert
BACKGROUND: The hepatic volume gain following resection is essential for clinical recovery. Previous studies have focused on cellular regeneration. This study aims to explore the rate of hepatic regeneration of the porcine liver following major resection, highlighting estimates of the early microarchitectural changes that occur during the cellular regeneration. METHODS: Nineteen large white pigs had 75% resection with serial measurements of the hepatic volume, density, blood flow, and architectural changes...
February 13, 2019: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30726832/can-surgical-registrars-accurately-identify-the-urgent-from-the-non-urgent-patient-presenting-with-acute-abdominal-pain
#3
Kirsten J de Burlet, Anna B M Lam, Simon J Harper, Peter D Larsen, Elizabeth R Dennett
BACKGROUND: Acute abdominal pain is a common surgical presentation with a wide range of causes. Differentiating urgent patients from non-urgent patients is important to optimise patient outcomes and the use of hospital resources. The aim of this study was to determine how accurately urgent and non-urgent patients presenting with abdominal pain can be identified. METHODS: A prospective study of consecutive patients admitted with abdominal pain was undertaken. Urgent patients were classified as requiring treatment (theatre, intensive care unit, endoscopy, or radiologic drainage) within 24 h...
February 6, 2019: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30726831/vascular-biomaterial-banking-in-academia
#4
Maani Hakimi, Markus Wortmann, Dittmar Böckler, Peter Schirmacher, Esther Herpel, Andreas S Peters
BACKGROUND/PURPOSE: To establish a high-quality vascular biomaterial bank to serve vascular research teams and act as a basis for translational medicine. The aim was to collect and store material so that investigation into the pathogenesis of vascular disease would be possible employing methods based on histopathology and/or molecular biology. METHODS: The Vascular Biomaterialbank Heidelberg (VBBH) evolved as part of an established, partly accredited biobank complex at the University of Heidelberg (BioMaterialBank Heidelberg - BMBH)...
February 6, 2019: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30650425/downregulation-of-sparc-is-associated-with-epithelial-mesenchymal-transition-and-low-differentiation-state-of-biliary-tract-cancer-cells
#5
Ughur Aghamaliyev, Haristi Gaitantzi, Maria Thomas, Katja Simon-Keller, Timo Gaiser, Alexander Marx, Vugar Yagublu, Joaquin Araos, Chen Cai, Nektarios A Valous, Niels Halama, Tobias Kiesslich, Matthias Ebert, Robert Grützmann, Felix Rückert, Katja Breitkopf-Heinlein
BACKGROUND: Biliary tract cancers (BTCs) have a poor prognosis. BTCs are characterized by a prominent desmoplastic reaction which possibly contributes to the aggressive phenotype of this tumor. The desmoplastic reaction includes excessive production and deposition of extracellular matrix proteins such as periostin, secreted protein acidic and rich in cysteine (SPARC), thrombospondin-1, as well as accumulation of α-smooth muscle actin-positive cancer-associated fibroblasts and immune cells, secreting growth factors and cytokines including transforming growth factor (TGF)-β...
January 16, 2019: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30884487/abstracts-136th-congress-of-the-german-society-of-surgery-dgch
#6
(no author information available yet)
No abstract text is available yet for this article.
2019: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30554221/the-short-and-long-term-outcomes-in-elderly-patients-with-hepatocellular-carcinoma-after-curative-surgery-a-case-controlled-study-with-propensity-score-matching
#7
Yukiyasu Okamura, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhiko Uesaka
BACKGROUND: With aging populations increasing in developed countries, the prevalence of elderly patients with hepatocellular carcinoma (HCC) is expected to rise. The aim of this study was to determine the short- and long-term outcomes of HCC surgery in elderly patients (≥75 years) using propensity score matching. METHODS: The study group included 421 patients who underwent hepatectomy as their initial treatment with curative intent. The patients were divided into elderly (n = 111) and non-elderly (n = 310) groups...
December 14, 2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30537714/glp1-receptor-agonist-liraglutide-is-an-effective-therapeutic-option-for-perioperative-glycemic-control-in-type-2-diabetes-within-enhanced-recovery-after-surgery-eras-protocols
#8
Shizuka Kaneko, Youhei Ueda, Yumiko Tahara
BACKGROUND: Enhanced Recovery After Surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery after surgical procedures by maintaining preoperative organ function and reducing profound stress responses following surgery [Wilmore and Kehlet: BMJ 2001; 322(7284): 473-6]. Glucagon-like peptide-1 receptor agonists (GLP-1RAgs), such as liraglutide, have recently been widely used as antidiabetic agents in patients with type 2 diabetes (T2D) because they maintain blood glucose at an ideal level throughout the day, including during postprandial periods, thereby improving hypoglycemia and body weight more than insulin therapies...
December 11, 2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30466084/microsurgical-technique-of-locoregional-injection-into-the-hepatic-artery-in-tumor-bearing-mice
#9
Baifeng Qian, Felix Strübing, Zhe Wang, Arianeb Mehrabi, Eduard Ryschich
BACKGROUND: Intraarterial injection into the hepatic artery represents an important route for locoregional administration for the treatment of hepatic tumors. In the present work, we describe microsurgical methodology for injection into the hepatic artery in mice. The technique was recently used for analysis of the phenomenon of endothelial capture in liver tumors. METHODS: Two different models of hepatic tumors in C57BL/6 mice were used. Tumors were induced by intrahepatic cell inoculation...
November 22, 2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30453288/predictive-early-recurrence-factors-of-preoperative-clinicophysiological-findings-in-pancreatic-cancer
#10
Shuji Suzuki, Mitsugi Shimoda, Jiro Shimazaki, Tsunehiko Maruyama, Yukio Oshiro, Kiyotaka Nishida, Yatsuka Sahara, Yuichi Nagakawa, Akihiko Tsuchida
BACKGROUND: We aimed to evaluate the use of preoperative clinicophysiological parameters as predictive risk factors for early recurrence of pancreatic ductal adenocarcinoma (PDAC) after curative resection. METHODS: A total of 260 patients who underwent pancreatic resection for PDAC between 2007 and 2015 were examined retrospectively. We divided the patients into those with early recurrence (within 6 months; group A, n = 52) and those with relapse within ≥6 months or without recurrence (group B, n = 208)...
November 19, 2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30419560/isoform-dependent-changes-in-cytochrome-p450-mediated-drug-metabolism-after-portal-vein-ligation-in-the-rat
#11
Tibor Kovács, Máté Déri, András Fülöp, Tímea Pálházy, Edit Háfra, Dávid Sirok, Ádám Ferenc Kiss, Gábor Lotz, Attila Szijártó, Katalin Monostory
BACKGROUND: Surgical removal of complicated liver tumors may be realized in two stages via selective portal vein ligation, inducing the atrophy of portally ligated lobes and the compensatory hypertrophy of nonligated liver lobes. Unlike morphological changes, functional aspects such as hepatic cytochrome P450 (CYP)-mediated drug metabolism remain vaguely understood, despite its critical role in both drug biotransformation and hepatic functional analysis. Our goal was the multilevel characterization of hepatic CYP-mediated drug metabolism after portal vein ligation in the rat...
November 12, 2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30419555/a-new-physiologic-mouse-model-of-one-anastomosis-gastric-bypass
#12
Andreas Kroh, Roman M Eickhoff, Daniel Heise, Patrick H Alizai, Karl P Rheinwalt, Ulf P Neumann, Florian T Ulmer
BACKGROUND: One anastomosis gastric bypass (OAGB) is a modern metabolic operation that has been demonstrated to be a rapid, safe, and effective procedure. As for other bariatric operations, the mechanisms and long-term effects of this procedure remain largely unknown and are difficult to address in human studies. Here, we present a new physiologic mouse model for mechanistic and long-term investigations. METHODS: Six-week-old C57Bl/6 mice were fed a high-fat diet for 12 weeks and scheduled for OAGB or sham operation...
November 12, 2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30544106/biology-based-surgery-the-extent-of-lymphadenectomy-in-cancer-of-the-colon
#13
REVIEW
Wouter Willaert, Sarah Cosyns, Wim Ceelen
The progression of colon cancer (CC) involves hematogenous and lymphatic spread to locoregional lymph nodes (LN), distant LN, and metastatic sites including the liver. The biological mechanisms that govern CC progression remain elusive. The Halsted model assumes an orderly, stepwise progression from the primary tumor to nearby nodes, henceforth to anatomically more distant nodes, and ultimately to distant organs. The Fisher model, on the other hand, regards the release of metastatic cells as early and essentially random events...
2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30537705/biology-of-nodal-spread-in-colon-cancer-insights-from-molecular-and-genetic-studies
#14
REVIEW
Pridvi Kandagatla, Lilias H Maguire, Karin M Hardiman
Colorectal cancer (CRC) lymph node metastases are common but their genetics and the mechanism whereby these metastases occur are not well understood. Here we present recent data regarding genetic heterogeneity in primary CRCs and their metastasis. In addition, we explain the different potential models describing the mechanisms of metastasis and the data supporting them. Multiple studies have also revealed a variety of prognostic molecular markers that are associated with lymph node metastasis in CRC. A better understanding of genetic heterogeneity and the mechanisms of metastasis is critical to predicting clinical response and resistance to targeted therapy...
2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30458448/the-53rd-congress-of-the-european-society-for-surgical-research
#15
(no author information available yet)
No abstract text is available yet for this article.
2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30244256/the-crucial-role-of-vascularization-and-lymphangiogenesis-in-skin-reconstruction
#16
REVIEW
Florian S Frueh, Nadia Sanchez-Macedo, Maurizio Calcagni, Pietro Giovanoli, Nicole Lindenblatt
BACKGROUND: The treatment of extensive skin defects and bradytrophic wounds remains a challenge in clinical practice. Despite emerging tissue engineering approaches, skin grafts and dermal substitutes are still the routine procedure for the majority of skin defects. Here, we review the role of vascularization and lymphangiogenesis for skin grafting and dermal substitutes from the clinician's perspective. SUMMARY: Graft revascularization is a dynamic combination of inosculation, angiogenesis, and vasculogenesis...
2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30244254/panta-rhei-neovascularization-angiogenesis-and-nutritive-perfusion-in-wound-healing
#17
REVIEW
Heiko Sorg, Daniel J Tilkorn, Ursula Mirastschijski, Joerg Hauser, Robert Kraemer
BACKGROUND: In response to tissue damage, angiogenesis is an extremely dynamic process that is finely regulated by signals from cells, the surrounding extracellular matrix (ECM), and derived mediators. As the only process, angiogenesis remains of decisive importance in the context of the entire wound healing process and is subject to constant change. The dissolution of the endothelial basement membrane, the migration of endothelial cells, and the development of new capillary vessels during wound healing depend not only on the cells and cytokines present, but also on the production and organization of ECM components in the immediate wound...
2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30244251/cell-sheet-based-vascularized-myocardial-tissue-fabrication
#18
REVIEW
Hyoe Komae, Minoru Ono, Tatsuya Shimizu
BACKGROUND: The development of regenerative medicine in recent years has been remarkable as tissue engineering technology and stem cell research have advanced. The ultimate goal of regenerative medicine is to fabricate human organs artificially. If fabricated organs can be transplanted medically, it will be the innovative treatment of diseases for which only donor organ transplantation is the definitive therapeutic method at present. SUMMARY: Our group has reported successful fabrication of thick functional myocardial tissue in vivo and in vitro by using cell sheet engineering technology which requires no scaffolds...
2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30244245/platelet-rich-plasma-in-tissue-engineering-hype-and-hope
#19
REVIEW
Siegmund Lang, Markus Loibl, Marietta Herrmann
BACKGROUND: Platelet-rich plasma (PRP) refers to an enriched platelet suspension in plasma. In addition to the clinical application of PRP in the context of various orthopedic diseases and beyond, PRP and platelet lysate (PL) have been in focus in the field of tissue engineering. In this review, we discuss the application of PRP as a cell culture supplement and as part of tissue engineering strategies, particularly emphasizing current hurdles and ambiguities regarding the efficacy of PRP in these approaches...
2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://read.qxmd.com/read/30244243/vascularization-regeneration-and-tissue-engineering
#20
EDITORIAL
Matthias W Laschke, Brigitte Vollmar
No abstract text is available yet for this article.
2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
journal
journal
22079
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"