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European Neurology

Mohamed Awadallah, Frank Janssen, Barbara Körber, Lorenz Breuer, Mateusz Scibor, René Handschu
INTRODUCTION: While there are several studies on reliability of telemedicine in assessing stroke scales, little is known about the validity of a general neurological examination performed via telemedicine. Therefore, we sought to test the agreement between bedside and remote examination in acute patients of the emergency room. METHODS: Acute patients at the emergency room of a 450-bed academic teaching hospital were included in this study. A clinical neurological examination consisting of 22 items was performed at bedside and also remotely via an audio-visual link by a different neurologist; both were experienced clinicians at the consultant level...
February 15, 2019: European Neurology
Xiao-Wei Xing, Jia-Tang Zhang, Yu-Bao Ma, Xiao-Yan Chen, Lei Wu, Xiao-Lin Wang, Hong-Fen Wang, Rong-Fei Wang, Fei Yang, Sheng-Yuan Yu
BACKGROUND: There are sparse and limited studies on small sample size reporting the application of next-generation sequencing (NGS) in the detection of central nervous system (CNS) viral infections. We assessed the diagnostic performance of NGS of cerebrospinal fluid (CSF) for predicting viral infections of the CNS caused by the neurotropic herpes viruses in a pilot population. MATERIALS AND METHODS: We prospectively collected CSF samples from 24 patients with CNS viral infection from April 2017 to October 2018...
February 14, 2019: European Neurology
Siripan Phattanarudee, Sunisa Sangthong, Roongroj Bhidayasiri
BACKGROUND: Sleep disturbance is a common problem among patients with Parkinson's disease (PD). OBJECTIVES: To investigate the prevalence of daytime somnolence and night-time sleep disturbances; to characterise the night-time sleep disturbance in patients with daytime somnolence; and to determine the correlation between daytime somnolence and night-time sleep disturbances. METHODS: One hundred and sixty patients with PD were included in the study...
February 7, 2019: European Neurology
Shuyi Shang, Wenbo Zhao, Chuanhui Li, Kai Dong, Haiqing Song, Ran Meng, Changhong Ren, Jiangang Duan, Xunming Ji
BACKGROUND AND PURPOSE: Intravenous thrombolysis is known as the only effective reperfusion therapy for acute ischemic stroke (AIS) caused by small branches occlusion. However, it is still unclear whether intra-arterial thrombolysis (IAT) is safe and effective for patients without detectable arterial occlusion. This study evaluated the safety and efficacy of IAT in these patients. METHODS: Data were collected on consecutive patients from December 2012 to February 2017 at the Xuanwu Hospital, Capital Medical University...
February 7, 2019: European Neurology
Mina Mirahmadi, Mohammad Taghi Karimi, Amir Esrafilian
BACKGROUND: Postural instability is a common disorder in Parkinson's disease (PD). The aim of this study was to evaluate stance stability of the subjects at the early stage of PD with both linear and nonlinear approaches. Moreover, this study aimed to find the effect of visual control on quiet stance postural control in these patients. METHOD: Seventeen PD patients (Hoehn/Yahr scale: 1) and 17 healthy control subjects were instructed to maintain quiet postural stance in 2 conditions (opened eyes and closed eyes)...
February 7, 2019: European Neurology
Cindy W Yoon, Hee-Kwon Park, Joung-Ho Rha
Systemic vasculitis, which can involve the brain, may be one of the causes of stroke in young adults; therefore, a test panel for systemic vasculitis is considered for some young stroke patients. However, little is known about this test's yield as a screening test in young adults with ischemic stroke. We evaluated the yield of a panel for systemic vasculitis as a screening test in young patients with ischemic stroke. Consecutive patients aged 18-45 years with ischemic stroke between January 2010 and December 2017 were included...
February 4, 2019: European Neurology
Pia De Stefano, Andreas Kleinschmidt, Margitta Seeck
No abstract text is available yet for this article.
February 4, 2019: European Neurology
Songul Senadim, Ersin Uygun, Mucahid Erdogan, Ayhan Koksal, Aysun Soysal, Dilek Atakli
BACKGROUND: The humanitarian response for Syria has been largely managed either from within Syria or from neighboring countries, particularly Turkey. This study was aimed at determining the sociodemographic and clinical profiles of Syrian asylum-seekers admitted to our clinic, changes in patient number across years, and the percentage of patients on follow-ups. METHODS: Syrian patients who were admitted to the neurology outpatient clinics, neurology emergency department (ED), and hospitalized in the neurology clinics were included in the study...
February 4, 2019: European Neurology
Shinya Tomari, Tomotaka Tanaka, Soichiro Matsubara, Kazuki Fukuma, Masafumi Ihara, Kazuyuki Nagatsuka, Kazunori Toyoda
BACKGROUND: Status epilepticus (SE) sometimes occurs after stroke. SE is classified as convulsive SE (CSE) and nonconvulsive SE (NCSE). Clinical characteristics, outcomes, mortality, and recurrences of post-stroke NCSE are yet to be clarified. METHODS: We retrospectively identified post-stroke SE patients between April 2010 and September 2015, with follow-ups continued until March 2016. We compared baseline clinical characteristics (age, sex, past history of epilepsy, early seizure, stroke type, and localization) between the CSE and NCSE groups...
February 4, 2019: European Neurology
Agata Czarnowska, Katarzyna Kapica-Topczewska, Olga Zajkowska, Renata Świerzbińska, Monika Chorąży, Joanna Tarasiuk, Joanna Zajkowska, Jan Kochanowicz, Alina Kułakowska
BACKGROUND: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that leads to inflammation, demyelination and neurodegeneration. Viral aetiology has been suspected to be an MS trigger for a long time, and herpesviruses (HSs) are among the potential pathogens involved. OBJECTIVES: The present investigation aims to detect the presence of antibodies against the herpes simplex virus (HSV), varicella-zoster virus, Epstein-Barr virus (EBV), human cytomegalovirus (CMV) and human herpesvirus 6 (HHV6) in the serum of MS patients and control individuals in north-eastern Poland...
January 18, 2019: European Neurology
Kang Min Park, Sung Eun Kim, Byung In Lee, Yun Jung Hur
BACKGROUND: We aimed to evaluate the brain morphology of patients with genetic generalized epilepsy (GGE) compared to healthy subjects. In addition, we investigated whether there are differences in brain morphology among different GGE syndromes. METHODS: We enrolled 100 patients with a clinical diagnosis of GGE. The patients were classified into different syndrome groups according to their predominant seizure type, age of seizure onset, and electroencephalography characteristics (12 childhood absence epilepsy [AE], 13 juvenile AE, 56 juvenile myoclonic epilepsy, and 19 epilepsy with generalized tonic-clonic alone)...
January 18, 2019: European Neurology
Maria-Ioanna Stefanou, Sophia Peloponnissiou-Vassilacos
Angelos Katakouzenos, a Greek neurologist and prolific medical writer at the beginning of the 20th century, belonged to a group of artists and scholars that formed the "generation of the 30s," a cultural movement that emerged after World War I and introduced modernism in Greek art and literature. Born in 1902, Katakouzenos studied medicine in France at the Universities of Montpellier and Paris, where he trained in neurology and -psychiatry under Georges Guillain, Henri Claude, Jean-Athanase Sicard, Pierre Marie, Clovis Vincent and Théophile -Alajouanine...
January 15, 2019: European Neurology
Filipa Ladeira, Manuel Salavisa, André Caetano, Raquel Barbosa, Francisca Sá, Ana Sofia Correia
BACKGROUND: Hormonal variations are known to influence the course of multiple sclerosis (MS). OBJECTIVES: We aimed to evaluate the impact of menopause in MS course, including disease activity and disability progression. METHODS: We conducted a retrospective longitudinal cohort study including all women, older than 44, post-menopausal, with a diagnosis of MS at least 1 year before menopause. We evaluated the impact of menopause in MS course comparing clinical and radiologic outcomes within 5 years before and after menopause...
January 15, 2019: European Neurology
Esther Ruberte, Tim Sinnecker, Michael Amann, Laura Gaetano, Yvonne Naegelin, Iris-Katharina Penner, Jens Kuhle, Tobias Derfuss, Ludwig Kappos, Cristina Granziera, Jens Wuerfel, Özgür Yaldizli
BACKGROUND: Structural Image Evaluation using Normalization of Atrophy (SIENA) is used to measure brain atrophy in multiple sclerosis (MS). However, brain extraction is prone to artefacts in the upper and lower parts of the brain. To overcome these shortcomings, some pivotal MS trials used a central slab instead of the whole brain as input for SIENA. The aim of this study was to compare the internal consistency and statistical dispersion of atrophy measures, associations with clinical outcomes and required sample sizes in clinical trials between these two approaches...
January 3, 2019: European Neurology
Hendrik Schulz, Jianghai Ruan, Rüdiger J Seitz
PURPOSE: Epilepsy has a complex interaction with sleep. The purpose of this study was to explore the relation between spontaneous arm movements and sleep architecture in patients with epilepsy. METHODS: This prospective study included 53 patients with suspected epilepsy (44 ± 18 years; 30 females, 23 males) and 55 age-matched patients with non-epileptic seizures (42 ± 15: 27 females, 28 males). Twenty-four-hour-video-electroencephalography recordings were combined with accelerometry of movement activity of both arms using actiwatches...
January 2, 2019: European Neurology
Chunyan Lei, LianMei Zhong, Yifan Ling, Tao Chen
BACKGROUND AND PURPOSE: There are debates about the causative role of high blood glucose in cerebral small vessel disease. The relationship between cerebral microbleeds (CMBs) and blood glucose is unclear. METHODS: Patients admitted to our department with acute ischaemic stroke were consecutively and prospectively included. Baseline demographic and clinical covariates were collected and analyzed according to the occurrence and location of CMBs and levels of blood glucose...
December 20, 2018: European Neurology
Takeo Matsubara, Keisuke Suzuki, Hiroaki Fujita, Yuji Watanabe, Hirotaka Sakuramoto, Masanori Matsubara, Koichi Hirata
OBJECTIVE: The objective of this study was to clarify the relationship between autonomic and non-autonomic non-motor symptoms in patients with Parkinson's disease (PD). METHODS: Sixty-five PD patients were included in this study (27 men and 38 women; aged 68.5 ± 10.0; Hoehn and Yahr (HY) stage 2.6 ± 1.1). The autonomic symptoms were evaluated by the Japanese version of the Scales for outcomes in PD autonomic (SCOPA-AUT) questionnaire. The patients were assessed with the mini-mental state examination (MMSE), PD sleep evaluation scale-2 (PDSS-2), Epworth sleepiness scale (ESS) and Beck's depression inventory II (BDI-II)...
December 20, 2018: European Neurology
Stefanie Völk, Uwe Koedel, Hans-Walter Pfister, Roland Schwankhart, Mark Op den Winkel, Konstanze Mühlbauer, Matthias Klein
BACKGROUND: The approach to unconscious patients in the emergency department (ED) is difficult, often depends on local resources and interests, and workup strategies often lack standardization. One reason for this is that data on causes, management, and outcome of patients who present to the ED with sudden onset unconsciousness of unknown cause is limited. OBJECTIVES: This study was performed to analyze the causes of acute impaired consciousness in patients in an interdisciplinary ED...
December 12, 2018: European Neurology
Gui-Fang Cao, Wei Liu, Qi Bi
OBJECTIVE: To explore the relationship between infective endocarditis (IE) and stroke. METHODS: The clinical data of patients diagnosed with IE from January 2003 to December 2017 in Beijing Anzhen Hospital Affiliated to Capital Medical University were retrospectively analyzed. RESULTS: A total of 861 patients (mean age: 40.79 ± 16.27 [SD]) with IE was recruited. Vegetations were confirmed in 97.32% of all the patients, among whom 296 were diagnosed with congenital heart disease and another 53 with rheumatic valvular disease...
November 28, 2018: European Neurology
Dimitri Renard, Marie De Verdal, Caroline Arquizan, Nicolas Menjot de Champfleur, Eric Thouvenot
No abstract text is available yet for this article.
November 21, 2018: European Neurology
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