Panagiota Tzani-Tzanopoulou, Ramazan Rozumbetov, Styliani Taka, Anastassios Doudoulakakis, Evangelia Lebessi, Nina Chanishvili, Elene Kakabadze, Nata Bakuradze, Nino Grdzelishvili, Marina Goderdzishvili, Evangelia Legaki, Evangelos Andreakos, Maria Papadaki, Spyridon Megremis, Paraskevi Xepapadaki, Grigoris Kaltsas, Cezmi A Akdis, Nikolaos G Papadopoulos
Bacteriophages represent the most extensive group of viruses within the human virome and have a significant impact on general health and well-being by regulating bacterial population dynamics. Staphylococcus aureus , found in the anterior nostrils, throat and skin, is an opportunistic pathobiont that can cause a wide range of diseases, from chronic inflammation to severe and acute infections. In this study, we developed a human cell-based homeostasis model between a clinically isolated strain of S. aureus 141 and active phages for this strain (PYOSa141 ) isolated from the commercial Pyophage cocktail (PYO)...
December 2022: Journal of General Virology