Grant L Hom, Blanche L Kuo, James H Ross, Graham C Chapman, Neha Sharma, Resya Sastry, Justin C Muste, Tyler E Greenlee, Thais F Conti, Rishi P Singh, Sumit Sharma
OBJECTIVE: Pentosan polysulphate (PPS; ELMIRON, Janssen Pharmaceuticals, Titusville, NJ) is a U.S. Food and Drug Administration-approved oral medication for interstitial cystitis. Numerous reports have been published detailing retinal toxicity with the use of PPS. Studies characterizing this condition are primarily retrospective, and consequently, alert and screening systems need to be developed to actively screen for this disease. The goal of this study was to characterize ophthalmic monitoring trends of a PPS-using patient sample to construct an alert and screening system for monitoring this condition...
March 3, 2023: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie