journal
MENU ▼
Read by QxMD icon Read
search

Annals of Pharmacotherapy

journal
https://read.qxmd.com/read/30854862/impact-of-a-direct-oral-anticoagulant-population-management-tool-on-anticoagulation-therapy-monitoring-in-clinical-practice
#1
Daniela Valencia, Patrick Spoutz, Jaclyn Stoppi, Jeffery L Kibert, Arthur Allen, David Parra, Augustus Hough
BACKGROUND: The optimal monitoring and follow-up strategy for long-term direct oral anticoagulant (DOAC) therapy has not been established. Historically, at our medical center, DOAC patients were referred to a clinical pharmacy specialist managed anticoagulation clinic (AC) for monitoring via regularly scheduled encounters (face-to-face or telephone). OBJECTIVE: To determine if implementation of a DOAC Population Management Tool (PMT) designed to identify patients who most likely require clinical review and possibly intervention, would improve the efficacy (interventions per patient) and efficiency (time invested to generate an intervention) of monitoring over AC practices...
March 10, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30841702/no-loose-ends-a-review-of-the-pharmacotherapy-of-hairy-cell-and-hairy-cell-leukemia-variant
#2
Amber C King, Charlene C Kabel, Jeremy J Pappacena, Sarah E Stump, Ryan J Daley
OBJECTIVE: To review the literature for the treatment of classical and variant hairy cell leukemia (HCL, HCLv), evaluating efficacy, safety, and supportive care involved in the use of purine analogues (PAs), interferon, BRAF inhibitors, monoclonal antibodies, Bruton's tyrosine kinase inhibitors, and new immunotoxin, moxetumomab pasudotox-tdfk (MPT). An electronic literature search of PubMed (January 1958 to January 2019) was conducted in PubMed using the MESH terms hairy cell leukemia, hairy cell leukemia variant, cladribine, pentostatin, rituximab, interferon, vemurafenib, moxetumomab pasudotox...
March 6, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30829052/assessment-of-condition-and-medication-knowledge-gaps-among-atrial-fibrillation-patients-a-systematic-review-and-meta-analysis
#3
Shahrzad Salmasi, Mary A De Vera, Arden Barry, Nick Bansback, Mark Harrison, Larry D Lynd, Peter S Loewen
BACKGROUND: Patient education facilitates construction of a correct illness representation, improves beliefs about medications, and improves knowledge, factors that have been associated with better adherence. OBJECTIVE: Our objective was to characterize the published literature about atrial fibrillation (AF) patients' disease and medication knowledge to identify knowledge gaps and misconceptions to inform AF patient education strategies. METHODS: Following PRISMA guidelines, we searched PubMed, EMBASE, CINAHL, and PsychINFO from inception to May 2018 for studies that assessed AF patients' knowledge about their condition and medications...
March 2, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30813769/erenumab-a-first-in-class-monoclonal-antibody-for-migraine-prevention
#4
Scott G Garland, Steven M Smith, John G Gums
OBJECTIVE: To review the pharmacology, efficacy, and safety of the calcitonin gene-related peptide (CGRP) inhibitor erenumab for migraine preventive therapy. DATA SOURCES: A MEDLINE/PubMed search (January 2000 to January 2019) was conducted using the keywords erenumab-aooe, erenumab, migraine, migraine prophylaxis, migraine prevention, and chronic migraine. Additional articles were identified by hand from references. STUDY SELECTION AND DATA EXTRACTION: We included English-language articles (excluding poster presentations) evaluating erenumab pharmacology, efficacy, or safety in humans for migraine prevention...
February 27, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30813760/copanlisib-an-intravenous-phosphatidylinositol-3-kinase-pi3k-inhibitor-for-the-treatment-of-relapsed-follicular-lymphoma
#5
Adel Eltantawy, Ximena Vallejos, Elrodia Sebea, Kirsten Evans
OBJECTIVE: To review the mechanism of action, clinical efficacy, safety, dosage, administration, and role of copanlisib in the treatment of relapsed follicular lymphoma (FL). DATA SOURCES: Sources of information were identified through searches of PubMed (August 2014 to January 2019) using the key terms copanlisib, Aliqopa, PI3K inhibitor, and BAY 80-6946. Unpublished abstract information was obtained from the American Society of Clinical Oncology. STUDY SELECTION AND DATA EXTRACTION: Review articles and studies in the English language evaluating the pharmacology, efficacy, and safety of copanlisib were included...
February 27, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30813754/andexanet-alfa-a-novel-factor-xa-inhibitor-reversal-agent
#6
Jason Powell, James Taylor, Scott G Garland
OBJECTIVE: The purpose of this article is to review the available clinical trial data for andexanet alfa and its role in clinical practice. DATA SOURCES: A MEDLINE/PubMed search was conducted (January 2000 to January 2019) using the keyword andexanet alfa for clinical trials. References of identified articles were searched by hand for additional citations. STUDY SELECTION AND DATA EXTRACTION: We included English-language articles related to the Food and Drug Administration (FDA) approval of andexanet alfa or provided novel information regarding this drug entity...
February 27, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30813752/ceftaroline-induced-thrombocytopenia-a-case-report
#7
Rachel S Britt, Jeffrey C Pearson, Monica V Mahoney, Alexa A Carlson
No abstract text is available yet for this article.
February 27, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30813751/comparing-anti-factor-xa-and-activated-partial-thromboplastin-levels-for-monitoring-unfractionated-heparin
#8
Rebekah A Wahking, Rachel H Hargreaves, Sean M Lockwood, Sabrina K Haskell, Kelly W Davis
BACKGROUND: Lab tests such as activated partial thromboplastin time (aPTT) or anti-factor Xa (anti-Xa) levels are typically used to monitor intravenous unfractionated heparin (IV heparin), with recent evidence suggesting that anti-Xa levels may provide a more accurate measure of anticoagulation. OBJECTIVE: The Lexington Veterans Affairs Health Care System transitioned from using aPTT to anti-Xa levels in January 2017. This study was conducted to evaluate the efficacy and safety of this change...
February 27, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30803256/severe-peripheral-edema-in-a-dabigatran-treated-patient
#9
Giuseppe Famularo
No abstract text is available yet for this article.
February 25, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30803243/octreotide-added-to-a-proton-pump-inhibitor-versus-a-proton-pump-inhibitor-alone-in-nonvariceal-upper-gastrointestinal-bleeds
#10
Heidi M Riha, Rachel Wilkinson, Jennifer Twilla, L Jeff Harris, Lauren A Kimmons, Mehmet Kocak, Megan A Van Berkel
BACKGROUND: Literature indicating clinically relevant benefits of an adjunctive somatostatin analog to standard therapies in nonvariceal upper-gastrointestinal bleeding (NVUGIB) is lacking. OBJECTIVE: The primary objective of this study was to find the association between outcomes in patients with NVUGIB treated with octreotide and a proton pump inhibitor (PPI; combination group) compared with those treated with a PPI alone. METHODS: We conducted a retrospective cohort study of adults admitted within a 5-hospital health care system with a NVUGIB treated with a PPI continuous infusion with or without an octreotide infusion...
February 25, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30788973/assessment-of-late-thromboembolic-complications-post-fontan-procedure-in-relation-to-different-antithrombotic-regimens-30-years-follow-up-experience
#11
Abdulrazaq S Al-Jazairi, Hana A Al Alshaykh, Giovanni Di Salvo, Edward B De Vol, Zohair Y Alhalees
BACKGROUND: The current CHEST guidelines recommend the use of antithrombotic therapy, either aspirin or warfarin, as a primary thromboembolic complications (TECs) prophylaxis in patients who undergo Fontan procedure, without specification on drug selection or duration of therapy. OBJECTIVE: To investigate the incidence rate of late TECs, occurring after 1-year post-Fontan procedure and to assess the difference in rate of late TECs between warfarin and aspirin. METHODS: A retrospective cohort study included patients who had Fontan procedures between 1985-2010 at our institution...
February 21, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30770025/managing-pharmacotherapy-in-people-living-with-hiv-and-concomitant-malignancy
#12
Jacqueline L Olin, Olga Klibanov, Alexandre Chan, Linda M Spooner
OBJECTIVE: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations for point-of-care review of combination therapies. DATA SOURCES: Literature searches were performed (2005 to December 2018) in MEDLINE and EMBASE to identify studies of malignancies in PLWH in the modern era. STUDY SELECTION AND DATA EXTRACTION: Article bibliographies and drug interaction databases were reviewed...
February 15, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30758229/dolutegravir-rilpivirine-dual-antiretroviral-therapy-for-the-treatment-of-hiv-1-infection
#13
E Kelly Hester, Kevin Astle
OBJECTIVE: To review the efficacy and safety of dolutegravir (DTG) with rilpivirine (RPV) as a dual therapy regimen in the treatment of HIV-1 infection. DATA SOURCES: A literature search was performed using PubMed (1966 to January 2019) and Google Scholar (2014 to January 2019) with the search terms dolutegravir, rilpivirine, dual, and switch. Other resources included review articles and the manufacturer product label. STUDY SELECTION AND DATA EXTRACTION: All relevant English-language articles of studies assessing the efficacy and safety of switch therapy to DTG with RPV and review articles were included...
February 13, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30758221/intravenous-olanzapine-for-the-management-of-agitation-review-of-the-literature
#14
Farah Khorassani, Maha Saad
OBJECTIVE: The purpose of this review is to summarize the current evidence of the off-label use of intravenous (IV) olanzapine and discuss its risks versus benefits for the management of agitation. DATA SOURCES: A literature search was conducted to gather relevant data regarding IV use of olanzapine for the management of acute agitation. PubMed, EMBASE, MEDLINE, and IPA were searched using the keywords and MESH terms: olanzapine, intravenous, IV, off-label, and agitation...
February 13, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30758220/effect-of-an-asthma-question-prompt-list-and-video-intervention-on-adolescents-medication-adherence-12-months-later
#15
Scott A Davis, Delesha Carpenter, Charles Lee, Nacire Garcia, Daniel S Reuland, Gail Tudor, Ceila E Loughlin, Betsy Sleath
BACKGROUND: Many adolescents do not obtain the maximum benefit from their asthma medications. Improving patient-provider communication may improve adolescents' asthma knowledge, adherence, and clinical outcomes. OBJECTIVE: To determine how a question prompt list and educational video intervention affect youth- and caregiver-reported medication adherence and self-reported medication problems. METHODS: Adolescents with persistent asthma (n = 359; 56...
February 13, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30739498/pharmacokinetics-and-safety-of-the-integrase-inhibitors-elvitegravir-and-dolutegravir-in-pregnant-women-with-hiv
#16
Binh Nguyen, Michelle M Foisy, Christine A Hughes
OBJECTIVE: To synthesize data on the pharmacokinetics and safety of dolutegravir and elvitegravir in pregnant women living with HIV. DATA SOURCES: A PubMed, EMBASE, Web of Science, and Google Scholar literature search (January 2010 to December 2018) was performed using the search terms dolutegravir, elvitegravir, women, pregnant*, and HIV. Additional reports were identified from conference abstracts and review of reference lists. STUDY SELECTION AND DATA EXTRACTION: English-language studies reporting pharmacokinetic and/or safety data in pregnant women receiving dolutegravir or elvitegravir/cobicistat were included...
February 10, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30739475/toxic-tacrolimus-concentrations-associated-with-intravenous-use-of-metoclopramide-in-a-lung-transplant-patient
#17
Alessio Provenzani, Natale D'alessandro, Piera Polidori
No abstract text is available yet for this article.
February 10, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30734587/a-retrospective-analysis-of-the-effects-of-chemotherapy-induced-neutropenia-on-overall-survival-in-patients-with-unresectable-or-metastatic-urothelial-carcinoma-to-gemcitabine-plus-cisplatin-combination-chemotherapy
#18
Keisuke Yamamoto, Tomomi Sasano, Daiki Tsuji, Yuichi Ishizuka, Umi Tokou, Hidenori Nakamichi, Tatsuaki Yoneda, Mitsuru Shiokawa, Katsushige Yabe
BACKGROUND: Chemotherapy-induced neutropenia (CIN) is an important dose-limiting toxicity of chemotherapy. However, evidence suggests that the occurrence of CIN may be predictive of treatment outcome. Indeed, studies have revealed that the onset of CIN is associated with a good chemotherapeutic response. OBJECTIVE: The purpose of this study was to investigate the association between the onset of CIN and overall survival in patients with unresectable or metastatic urothelial carcinoma (UC) who received a combination regimen of gemcitabine and cisplatin (GC)...
February 8, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30734567/vancomycin-versus-metronidazole-for-nonsevere-clostridioides-difficile-infection-are-the-data-adequate-to-change-practice
#19
Katherine V Sarna, Alan E Gross
OBJECTIVE: To compare oral metronidazole and vancomycin for the treatment of mild-to-moderate Clostridioides difficile infection (mmCDI). DATA SOURCES: A MEDLINE literature search (inception to November 2018) was performed using the search terms metronidazole, vancomycin, and Clostridium/Clostridioides difficile. Additional references were identified from a review of literature citations. STUDY SELECTION AND DATA EXTRACTION: All English-language clinical studies (interventional and observational), meta-analyses, and cost-effectiveness analyses comparing the efficacy of metronidazole and vancomycin for mmCDI were evaluated...
February 8, 2019: Annals of Pharmacotherapy
https://read.qxmd.com/read/30724102/evaluating-the-effect-of-a-patient-decision-aid-for-atrial-fibrillation-stroke-prevention-therapy
#20
Peter S Loewen, Nick Bansback, James Hicklin, Jason G Andrade, Anita I Kapanen, Leanne Kwan, Larry D Lynd, Alison McClean, Jenny MacGillivray, Shahrzad Salmasi
BACKGROUND: Stroke prevention therapy decisions for patients with atrial fibrillation (AF) are complex and require trade-offs, but few validated patient decision aids (PDAs) are available to facilitate shared decision making. OBJECTIVE: To evaluate the effects of a novel PDA on decision-making parameters for AF patients choosing stroke prevention therapy. METHODS: We developed an evidence-based individualized online AF PDA for stroke prevention therapy and evaluated it in a prospective observational pilot study...
February 6, 2019: Annals of Pharmacotherapy
journal
journal
20312
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"