journal
https://read.qxmd.com/read/38682541/changing-the-organizational-work-schedule-of-shift-workers-leads-to-improved-sleep-an-editorial
#1
JOURNAL ARTICLE
Annie Vallières, Megan R Crawford
No abstract text is available yet for this article.
April 29, 2024: Sleep
https://read.qxmd.com/read/38676404/interindividual-differences-in-mindfulness-are-linked-to-sleep-eeg-characteristics
#2
JOURNAL ARTICLE
M Wunderlin, M Studler, L R R Gianotti, M A Züst, D Knoch
STUDY OBJECTIVES: Mindfulness describes the ability to focus on the presence, including one's thoughts and feelings. Trait mindfulness - a person's inherent tendency to be mindful - has been connected to increased subjective sleep quality, but evidence from objective EEG-based sleep measures is lacking. Here, we investigate whether objective EEG-based sleep parameters explain interindividual differences in trait mindfulness. METHODS: Whole-night polysomnographic data were gathered from 52 healthy adults (27 females; agemean = 21...
April 27, 2024: Sleep
https://read.qxmd.com/read/38666299/impact-of-sleep-disturbance-in-shift-workers-on-hippocampal-volume-and-psychomotor-speed
#3
JOURNAL ARTICLE
Yumi Song, Shinhye Kim, Yoonji Joo, Eunji Ha, Youngeun Shim, Hyeonji Lee, Hyeonseok Jeong, In Kyoon Lyoo, Sujung Yoon, Suji Lee
STUDY OBJECTIVES: Shift work interferes with circadian rhythms, affecting sleep quality and cognitive function. Poor sleep quality in shift workers can impair psychomotor performance due to fatigue and sleepiness, increasing the risk of errors, accidents, and reduced productivity. Given the potential for atrophic changes in the hippocampus due to sleep disturbances, our study investigates how poor sleep quality correlates with hippocampal structural alterations and impacts psychomotor performance among shift workers...
April 26, 2024: Sleep
https://read.qxmd.com/read/38644625/effect-of-daridorexant-on-sleep-architecture-in-patients-with-chronic-insomnia-disorder-a-pooled-post-hoc-analysis-of-two-randomized-phase-3-clinical-studies
#4
JOURNAL ARTICLE
Tobias Di Marco, Ina Djonlagic, Yves Dauvilliers, Kolia Sadeghi, David Little, Alexandre N Datta, Jeffrey Hubbard, Göran Hajak, Andrew Krystal, Antonio Olivieri, Liborio Parrino, Corey B Puryear, Gary Zammit, Jacob Donoghue, Thomas E Scammell
STUDY OBJECTIVES: Post-hoc analysis to evaluate the effect of daridorexant on sleep architecture in people with insomnia, focusing on features associated with hyperarousal. METHODS: We studied sleep architecture in adults with chronic insomnia disorder from two randomized Phase 3 clinical studies (Clinicaltrials.gov: NCT03545191 and NCT03575104) investigating 3 months of daridorexant treatment (placebo, daridorexant 25 mg, daridorexant 50 mg). We analyzed sleep-wake transition probabilities, EEG spectra and sleep spindle properties including density, dispersion, and slow oscillation phase coupling...
April 22, 2024: Sleep
https://read.qxmd.com/read/38635888/association-between-longitudinal-change-of-sleep-patterns-and-the-risk-of-cardiovascular-diseases
#5
JOURNAL ARTICLE
Lingfang He, Tianqi Ma, Xuerui Wang, Xunjie Cheng, Yongping Bai
STUDY OBJECTIVES: To investigate the role of longitudinal change of sleep patterns in the incidence of cardiovascular diseases (CVD). METHODS: Based on UK Biobank, a total of 18,172 participants were enrolled. Five dimensions of healthy sleep including early chronotype, sleep 7-8 hours/day, free of insomnia, no snoring, and no frequent excessive daytime sleepiness were used to generate a healthy sleep score (HSS) ranging from 0 to 5. Corresponding to the HSS of 0-1, 2-3, and 4-5, the poor, intermediate, and healthy sleep pattern were defined...
April 18, 2024: Sleep
https://read.qxmd.com/read/38634644/rem-sleep-is-reduced-in-late-middle-aged-and-older-apoe4-allele-carriers
#6
JOURNAL ARTICLE
Claire André, Marie-Ève Martineau-Dussault, Andrée-Ann Baril, Nicola Andrea Marchi, Véronique Daneault, Dominique Lorrain, Carol Hudon, Célyne H Bastien, Dominique Petit, Cynthia Thompson, Judes Poirier, Jacques Montplaisir, Nadia Gosselin, Julie Carrier
STUDY OBJECTIVES: Apolipoprotein E ɛ4 (APOE4) is the strongest genetic risk factor for Alzheimer's disease (AD). In addition, APOE4 carriers may exhibit sleep disturbances, but conflicting results have been reported, such that there is no clear consensus regarding which aspects of sleep are impacted. Our objective was to compare objective sleep architecture between APOE4 carriers and non-carriers, and to investigate the modulating impact of age, sex, cognitive status and obstructive sleep apnea...
April 18, 2024: Sleep
https://read.qxmd.com/read/38632974/is-sleep-the-new-treatment-for-pain-two-issues-need-resolving-before-deciding
#7
JOURNAL ARTICLE
David M Klyne, Michelle Hall
No abstract text is available yet for this article.
April 18, 2024: Sleep
https://read.qxmd.com/read/38629490/effect-of-dynamic-binaural-beats-on-sleep-quality-a-proof-of-concept-study-with-questionnaire-and-biosignals
#8
JOURNAL ARTICLE
Hwa-Ah-Ni Lee, Woo-Jin Lee, Seong-Uk Kim, Hyunji Kim, Minkyu Ahn, Jeong-Hee Kim, Do-Won Kim, Chang-Ho Yun, Han-Jeong Hwang
Binaural beat (BB) has been investigated as a potential modality to enhance sleep quality. In this study, we introduce a new form of BB, referred to as dynamic BB (DBB), which incorporates dynamically changing carrier frequency differences between the left and right ears. Specifically, the carrier frequency of the right ear varied between 100 and 103 Hz over a period, while the left ear remained fixed at 100 Hz, yielding a frequency difference range of 0 to 3 Hz. The objective of this study was to examine the effect of DBB on sleep quality...
April 17, 2024: Sleep
https://read.qxmd.com/read/38629438/the-nf%C3%AE%C2%BAb-dif-is-required-for-behavioral-and-molecular-correlates-of-sleep-homeostasis-in-drosophila
#9
JOURNAL ARTICLE
Michael K O'Hara, Christopher Saul, Arun Handa, Bumsik Cho, Xiangzhong Zheng, Amita Sehgal, Julie A Williams
The nuclear factor binding the κ light chain in B-cells (NFκB) is involved in a wide range of cellular processes including development, growth, innate immunity, and sleep. However, genetic studies of the role of specific NFκB transcription factors in sleep have been limited. Drosophila fruit flies carry three genes encoding NFκB transcription factors, Dorsal, Dorsal Immunity Factor (Dif), and Relish. We previously found that loss of the Relish gene from fat body suppressed daily nighttime sleep, and abolished infection-induced sleep...
April 17, 2024: Sleep
https://read.qxmd.com/read/38625730/clinical-efficacy-and-safety-of-intravenous-ferric-carboxymaltose-for-treatment-of-restless-legs-syndrome-a-multicenter-randomized-placebo-controlled-clinical-trial
#10
JOURNAL ARTICLE
Christopher J Earley, Diego García-Borreguero, Mark Falone, John W Winkelman
STUDY OBJECTIVES: Iron therapy is associated with improvements in restless legs syndrome (RLS). This multicenter, randomized, double-blind study evaluated the effect of intravenous ferric carboxymaltose (FCM) on RLS. METHODS: A total of 209 adult patients with a baseline International Restless Legs Syndrome (IRLS) score ≥15 were randomized (1:1) to FCM (750 mg/15 mL) or placebo on study Days 0 and 5. Ongoing RLS medication was tapered starting on Day 5, with the goal of discontinuing treatment or achieving the lowest effective dose...
April 16, 2024: Sleep
https://read.qxmd.com/read/38605676/pathogenesis-of-sleep-disordered-breathing-in-the-setting-of-opioid-use-a-multiple-mediation-analysis-using-physiology
#11
JOURNAL ARTICLE
Jeremy E Orr, Atul Malhotra, Eli Gruenberg, Traci Marin, Scott A Sands, Raichel M Alex, Robert L Owens, Christopher N Schmickl
STUDY OBJECTIVES: Opioid medications are commonly used and are known to impact both breathing and sleep, and are linked with adverse health outcomes including death. Clinical data indicate that chronic opioid use causes central sleep apnea, and might also worsen obstructive sleep apnea. The mechanisms by which opioids influence sleep-disordered breathing pathogenesis are not established. METHODS: Patients who underwent clinically-indicated polysomnography confirming sleep-disordered breathing (SDB) (AHI≥5/hr) were included...
April 12, 2024: Sleep
https://read.qxmd.com/read/38602244/longer-sleep-duration-in-alzheimer-s-disease-progression-a-compensatory-response
#12
EDITORIAL
Peng Li, Lei Gao, Brendan P Lucey, Yo-El S Ju, Erik S Musiek, Kun Hu
No abstract text is available yet for this article.
April 11, 2024: Sleep
https://read.qxmd.com/read/38602131/the-dynamic-responses-of-mood-and-sleep-physiology-to-chronic-sleep-restriction-and-subsequent-recovery-sleep
#13
JOURNAL ARTICLE
Christopher W Jones, Olivia Larson, Mathias Basner, David F Dinges
Healthy sleep of sufficient duration preserves mood and disturbed sleep is a risk factor for a range of psychiatric disorders. As adults commonly experience chronic sleep restriction (SR), an enhanced understanding of the dynamic relationship between sleep and mood is needed, including whether susceptibility to SR-induced mood disturbance differs between sexes. To address these gaps, data from N=221 healthy adults who completed one of two multi-day laboratory studies with identical 9-day SR protocols were analyzed...
April 11, 2024: Sleep
https://read.qxmd.com/read/38597884/insomnia-gone-in-one-week-without-medication-too-good-to-be-true
#14
JOURNAL ARTICLE
Célyne H Bastien, Ellemarije Altena
No abstract text is available yet for this article.
April 10, 2024: Sleep
https://read.qxmd.com/read/38587464/daily-associations-between-salivary-cortisol-and-eeg-assessed-sleep-a-15-day-intensive-longitudinal-study
#15
JOURNAL ARTICLE
Yang Yap, Natasha Yan Chi Tung, Lin Shen, Bei Bei, Andrew Phillips, Joshua F Wiley
STUDY OBJECTIVES: Current evidence suggests that cortisol levels are bi-directionally associated with sleep. However, the daily, naturalistic cortisol-sleep associations remain unclear, as current evidence is mostly cross-sectional. This study tested whether pre-sleep cortisol predicts sleep duration and quality, and whether these sleep parameters predict the following day's diurnal cortisol slope using a 15-day intensive longitudinal design with electroencephalographic measures and saliva sampling...
April 8, 2024: Sleep
https://read.qxmd.com/read/38581363/effects-of-a-work-schedule-with-abated-quick-returns-on-insomnia-sleepiness-and-work-related-fatigue-results-from-a-large-scale-cluster-randomized-controlled-trial
#16
JOURNAL ARTICLE
Ingebjørg Louise Rockwell Djupedal, Anette Harris, Erling Svensen, Ståle Pallesen, Siri Waage, Morten Birkeland Nielsen, Erlend Sunde, Bjørn Bjorvatn, Øystein Holmelid, Øystein Vedaa
STUDY OBJECTIVES: To investigate the effect of a work schedule with abated quick returns (i.e., >11 hours between two shifts) on insomnia, daytime sleepiness, and work-related fatigue compared to a shift schedule maintaining the usual number of quick returns. METHODS: A two-armed cluster randomized controlled trial including 66 units was conducted at a university hospital in Norway. Units with healthcare workers on rotating shift schedules were randomly assigned to a shift schedule with abated quick returns (intervention) or to continue with a schedule including quick returns as usual (control) for six months...
April 6, 2024: Sleep
https://read.qxmd.com/read/38571402/perturbation-of-the-insomnia-wdr90-gwas-locus-pinpoints-rs3752495-as-a-causal-variant-influencing-distal-expression-of-neighboring-gene-pig-q
#17
JOURNAL ARTICLE
Shilpa Sonti, Sheridan H Littleton, Matthew C Pahl, Amber J Zimmerman, Alessandra Chesi, Justin Palermo, Chiara Lasconi, Elizabeth B Brown, James A Pippin, Andrew D Wells, Fusun Doldur-Balli, Allan I Pack, Phillip R Gehrman, Alex C Keene, Struan F A Grant
Although genome wide association studies (GWAS) have identified loci for sleep-related traits, they do not directly uncover the underlying causal variants and corresponding effector genes. The majority of such variants reside in non-coding regions and are therefore presumed to impact cis-regulatory elements. Our previously reported 'variant-to-gene mapping' effort in human induced pluripotent stem cell (iPSC)-derived neural progenitor cells (NPCs), combined with validation in both Drosophila and zebrafish, implicated PIG-Q as a functionally relevant gene at the insomnia 'WDR90' GWAS locus...
April 4, 2024: Sleep
https://read.qxmd.com/read/38552004/correction-to-sleepmat-a-new-behavioral-analysis-software-program-for-sleep-and-circadian-rhythms
#18
(no author information available yet)
No abstract text is available yet for this article.
March 29, 2024: Sleep
https://read.qxmd.com/read/38551123/sphyncs-feasibility-of-long-term-monitoring-with-fitbit-smartwatches-in-central-disorders-of-hypersomnolence-and-extraction-of-digital-biomarkers-in-narcolepsy
#19
JOURNAL ARTICLE
Oriella Gnarra, Julia van der Meer, Jan D Warncke, Livia G Fregolente, Elena Wenz, Kseniia Zub, Uchendu Nwachukwu, Zhongxing Zhang, Ramin Khatami, Sigrid von Manitius, Silvia Miano, Jens Acker, Mathias Strub, Robert Riener, Claudio L A Bassetti, Markus H Schmidt
The Swiss Primary Hypersomnolence and Narcolepsy Cohort Study (SPHYNCS) is a multicenter research initiative to identify new biomarkers in central disorders of hypersomnolence (CDH). Whereas narcolepsy type 1 (NT1) is well characterized, other CDH disorders lack precise biomarkers. In SPHYNCS, we utilized Fitbit smartwatches to monitor physical activity, heart rate, and sleep parameters over one year. We examined the feasibility of long-term ambulatory monitoring using the wearable device. We then explored digital biomarkers differentiating patients with NT1 from healthy controls (HC)...
March 29, 2024: Sleep
https://read.qxmd.com/read/38531670/heart-rate-variability-analysis-in-obstructive-sleep-apnoea-patients-with-daytime-sleepiness
#20
JOURNAL ARTICLE
Seren Ucak, Hasthi U Dissanayake, Philip de Chazal, Yu Sun Bin, Kate Sutherland, Bianca Setionago, Benjamin Tong, Brendon J Yee, Kristina Kairaitis, John R Wheatley, Amanda J Piper, Peter A Cistulli
STUDY OBJECTIVES: Recent studies suggest sleepy patients with OSA are at higher risk for incident cardiovascular disease. This study assessed cardiac autonomic function in sleepy versus non-sleepy patients with obstructive sleep apnoea (OSA) using heart rate variability (HRV) analysis. We hypothesised that HRV profiles of sleepy patients would indicate higher cardiovascular risk. METHODS: Electrocardiograms (ECG) derived from polysomnograms (PSG) collected by the Sydney Sleep Biobank were used to study HRV in groups of sleepy (ESS≥10) and non-sleepy OSA patients (ESS<10)...
March 26, 2024: Sleep
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