Lawrence F Eichenfield, Linda Stein Gold, Leon H Kircik, William P Werschler, Kenneth Beer, Zoe D Draelos, Emil A Tanghetti, Kim A Papp, Hilary Baldwin, Edward Lain, Neil Sadick, Melinda J Gooderham, Adarsh Konda
BACKGROUND/OBJECTIVES: Topical clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel (IDP-126) is the first fixed-dose triple-combination formulation in development for acne. This post hoc analysis investigated efficacy and safety of IDP-126 in children and adolescents with moderate-to-severe acne. METHODS: In a randomized, double-blind phase 2 study (NCT03170388), participants ≥9 years of age with moderate-to-severe acne were eligible for randomization (1:1:1:1:1) to once-daily IDP-126, one of three dyad combination gels, or vehicle gel for 12 weeks...
March 22, 2023: Pediatric Dermatology