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Halinder S Mangat, Xian Wu, Linda M Gerber, Justin T Schwarz, Malik Fakhar, Santosh B Murthy, Philip E Stieg, Jamshid Ghajar, Roger Härtl
BACKGROUND: Hypertonic saline (HTS) and mannitol are effective in reducing intracranial pressure (ICP) after severe traumatic brain injury (TBI). However, their simultaneous effect on the cerebral perfusion pressure (CPP) and ICP has not been studied rigorously. OBJECTIVE: To determine the difference in effects of HTS and mannitol on the combined burden of high ICP and low CPP in patients with severe TBI. METHODS: We performed a case-control study using prospectively collected data from the New York State TBI-trac® database (Brain Trauma Foundation, New York, New York)...
March 16, 2019: Neurosurgery
Christian Lopez Ramos, Michael G Brandel, Robert C Rennert, Brian R Hirshman, Arvin R Wali, Jeffrey A Steinberg, David R Santiago-Dieppa, Mitchell Flagg, Scott E Olson, J Scott Pannell, Alexander A Khalessi
BACKGROUND: The "Volume Pledge" aims to centralize carotid artery stenting (CAS) to hospitals and surgeons performing ≥10 and ≥5 procedures annually, respectively. OBJECTIVE: To compare outcomes after CAS between hospitals and surgeons meeting or not meeting the Volume Pledge thresholds. METHODS: We queried the Nationwide Inpatient Sample for CAS admissions. Hospitals and surgeons were categorized as low volume and high volume (HV) based on the Volume Pledge...
March 15, 2019: Neurosurgery
Bertrand Mathon, Aymeric Amelot, Stéphane Clemenceau, Alexandre Carpentier, Anne-Laure Boch
No abstract text is available yet for this article.
March 15, 2019: Neurosurgery
Wyatt L Ramey, Christina M Walter, Jeffrey Zeller, Travis M Dumont, G Michael Lemole, R John Hurlbert
BACKGROUND: The border between the United States (US) and Mexico is an international boundary spanning 3000 km, where unauthorized crossings occur regularly. We examine patterns of neurotrauma, health care utilization, and financial costs at our level 1 trauma center incurred by patients from wall-jumping into the US. OBJECTIVE: To determine the clinical and socioeconomic consequences from neurotrauma as a result of jumping over the US-Mexico border wall. METHODS: Medical records of patients at (Banner University of Arizona Medical Center - Tucson) were retrospectively reviewed from January 2012 through December 2017...
March 15, 2019: Neurosurgery
Marc Zanello, Alim-Louis Benabid, Bertrand Devaux, Johan Pallud
No abstract text is available yet for this article.
March 15, 2019: Neurosurgery
Aditya V Karhade, Quirina C B S Thio, Paul T Ogink, Christopher M Bono, Marco L Ferrone, Kevin S Oh, Philip J Saylor, Andrew J Schoenfeld, John H Shin, Mitchel B Harris, Joseph H Schwab
BACKGROUND: Increasing prevalence of metastatic disease has been accompanied by increasing rates of surgical intervention. Current tools have poor to fair predictive performance for intermediate (90-d) and long-term (1-yr) mortality. OBJECTIVE: To develop predictive algorithms for spinal metastatic disease at these time points and to provide patient-specific explanations of the predictions generated by these algorithms. METHODS: Retrospective review was conducted at 2 large academic medical centers to identify patients undergoing initial operative management for spinal metastatic disease between January 2000 and December 2016...
March 14, 2019: Neurosurgery
Michael Karsy, Michael R Jensen, Jian Guan, Vijay M Ravindra, Erica F Bisson, William T Couldwell
BACKGROUND: Skull base meningioma management is complicated by their proximity to intracranial neurovascular structures because complete resection may pose a risk of worsening morbidity. OBJECTIVE: To assess the influence of clinical outcomes and surgical management on patient-perceived quality-of-life outcomes, value, and cost-effectiveness. METHODS: Patients who underwent resection of a skull base meningioma, had adequate clinical follow-up, and completed EQ-5D-3L questionnaires preoperatively and at 1 mo and 1 yr postoperatively were identified in a retrospective review...
March 14, 2019: Neurosurgery
Mario Teo, Sunil Furtado, Osamu F Kaneko, Tej D Azad, Venkatesh Madhugiri, Huy M Do, Gary K Steinberg
BACKGROUND: Traditional moyamoya disease (MMD) classification relies on morphological digital subtraction angiography (DSA) assessment, which do not reflect hemodynamic status, clinical symptoms, or surgical treatment outcome. OBJECTIVE: To (1) validate the new Berlin MMD preoperative symptomatology grading system and (2) determine the clinical application of the grading system in predicting radiological and clinical outcomes after surgical revascularization. METHODS: Ninety-six MMD patients (192 hemispheres) with all 3 investigations (DSA, magnetic resonance imaging [MRI], Xenon-CT) performed preoperatively at our institution (2007-2013) were included...
March 13, 2019: Neurosurgery
Osvaldo Vilela-Filho
No abstract text is available yet for this article.
March 13, 2019: Neurosurgery
Jason A Liew, Wuyang Yang, Leila A Mashouf, Sean Li, Justin M Caplan, Rafael J Tamargo, Judy Huang
BACKGROUND: Spontaneous obliteration (SpO) of untreated arteriovenous malformations (AVMs) is rare with fewer than 100 cases reported. The incidence and predisposing factors of SpO remain unclear, impeding our understanding of lesion progression in untreated patients. OBJECTIVE: To determine the incidence rate and predisposing factors of SpO in a North American cohort. METHODS: AVMs were retrospectively evaluated at our institution for over 25 yr...
March 13, 2019: Neurosurgery
(no author information available yet)
No abstract text is available yet for this article.
March 12, 2019: Neurosurgery
Ryan Hess, Karl R Abi-Aad, Matthew E Welz, Bernard R Bendok
No abstract text is available yet for this article.
March 12, 2019: Neurosurgery
Yuanxuan Xia, Risheng Xu, Thomas A Kosztowski, Seba Ramhmdani, A Karim Ahmed, Sheng-Fu L Lo, Ali Bydon
BACKGROUND: Few studies have described rates of proximal clinical adjacent segment pathology (CASP) after posterior cervical decompression and fusion (PCDF). OBJECTIVE: To investigate rates of proximal CASP at C2 vs C3 in PCDFs for degenerative spine disease. METHODS: A retrospective review of 380 cases of PCDF for degenerative disease with proximal constructs ending at C2 vs C3 was performed. Minimum follow-up was 12 mo. The primary outcome was proximal CASP requiring reoperation...
March 12, 2019: Neurosurgery
Adam A Dmytriw, Kevin Phan, Mohamed M Salem, Nimer Adeeb, Justin M Moore, Christoph J Griessenauer, Paul M Foreman, Hussain Shallwani, Hakeem Shakir, Adnan H Siddiqui, Elad I Levy, Jason M Davies, Mark R Harrigan, Ajith J Thomas, Christopher S Ogilvy
BACKGROUND: The Pipeline Embolization Device (PED; Medtronic, Dublin, Ireland) has become an important tool for the treatment of cerebral aneurysms. Since FDA approval, there are ongoing efforts to increase aneurysm occlusion rates and reduce the incidence of complications. OBJECTIVE: To assess aneurysm occlusion and complication rates over time. METHODS: Retrospective analysis of consecutive anterior circulation aneurysms treated with a single PED between 2011 and 2016 at 3 academic institutions in the US was performed...
March 12, 2019: Neurosurgery
Chen-Yu Ding, Han-Pei Cai, Hong-Liang Ge, Liang-Hong Yu, Yuang-Xiang Lin, De-Zhi Kang
BACKGROUND: The relationships between lipoprotein-associated phospholipase A2 (Lp-PLA2) level, vasospasm, and clinical outcome of patients with aneurysmal subarachnoid hemorrhage (aSAH) are still unclear. OBJECTIVE: To identify the associations between admission Lp-PLA2 and vasospasm following subarachnoid hemorrhage and the clinical outcome of aSAH. METHODS: A total of 103 aSAH patients who had Lp-PLA2 level obtained within 24 h postbleeding were included...
March 9, 2019: Neurosurgery
Cole A Bortz, Peter G Passias, Frank Segreto, Samantha R Horn, Virginie Lafage, Justin S Smith, Breton Line, Gregory M Mundis, Khaled M Kebaish, Michael P Kelly, Themistocles Protopsaltis, Daniel M Sciubba, Alexandra Soroceanu, Eric O Klineberg, Douglas C Burton, Robert A Hart, Frank J Schwab, Shay Bess, Christopher I Shaffrey, Christopher P Ames
BACKGROUND: Nonroutine discharge, including discharge to inpatient rehab and skilled nursing facilities, is associated with increased cost-of-care. Given the rising prevalence of cervical deformity (CD)-corrective surgery and the necessity of value-based healthcare, it is important to identify indicators for nonroutine discharge. OBJECTIVE: To identify factors associated with nonroutine discharge after CD-corrective surgery using a statistical learning algorithm...
March 8, 2019: Neurosurgery
Byungjun Kim, Byung Moon Kim, Oh Young Bang, Jang-Hyun Baek, Ji Hoe Heo, Hyo Suk Nam, Young Dae Kim, Joonsang Yoo, Dong Joon Kim, Pyoung Jeon, Seung Kug Baik, Sang Hyun Suh, Kyung-Yul Lee, Hyo Sung Kwak, Hong Gee Roh, Young-Jun Lee, Sang Heum Kim, Chang Woo Ryu, Yon-Kwon Ihn, Hong-Jun Jeon, Jin Woo Kim, Jun Soo Byun, Sangil Suh, Jeong Jin Park, Woong Jae Lee, Jieun Roh, Byoung-Soo Shin
BACKGROUND: It remains controversial whether carotid artery stenting (CAS) is needed in cases of tandem cervical internal carotid artery occlusion (cICAO) and intracranial large vessel occlusion (LVO). OBJECTIVE: To investigate the efficacy and safety of CAS in combination with endovascular thrombectomy (CAS-EVT) in cICAO-LVO patients and to compare its outcomes with those of EVT without CAS (EVT-alone). METHODS: We identified all patients who underwent EVT for tandem cICAO-LVO from the prospectively maintained registries of 17 stroke centers...
March 8, 2019: Neurosurgery
Michelle Ariana Wedemeyer, Frank Joseph Attenello
No abstract text is available yet for this article.
March 8, 2019: Neurosurgery
Robert C Nickl, Martin M Reich, Nicoló Gabriele Pozzi, Patrick Fricke, Florian Lange, Jonas Roothans, Jens Volkmann, Cordula Matthies
BACKGROUND: Clinical trials have established subthalamic deep-brain-stimulation (STN-DBS) as a highly effective treatment for motor symptoms of Parkinson disease (PD), but in clinical practice outcomes are variable. Experienced centers are confronted with an increasing number of patients with partially "failed" STN-DBS, in whom motor benefit doesn't meet expectations. These patients require a complex multidisciplinary and standardized workup to identify the likely cause. OBJECTIVE: To describe outcomes in a series of PD patients undergoing lead revision for suboptimal motor benefit after STN-DBS surgery and characterize selection criteria for surgical revision...
March 6, 2019: Neurosurgery
Eleonora F Spinazzi, Pavan S Upadhyayula, Guy M McKhann
No abstract text is available yet for this article.
March 6, 2019: Neurosurgery
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