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Lancet Neurology

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https://read.qxmd.com/read/30885508/global-burden-of-neurological-disorders-challenges-and-opportunities-with-the-available-data
#1
Henrik Toft Sørensen
No abstract text is available yet for this article.
March 15, 2019: Lancet Neurology
https://read.qxmd.com/read/30879893/global-regional-and-national-burden-of-neurological-disorders-1990-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#2
(no author information available yet)
BACKGROUND: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders. METHODS: We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016...
March 14, 2019: Lancet Neurology
https://read.qxmd.com/read/30879892/the-global-burden-of-neurological-disorders
#3
William M Carroll
No abstract text is available yet for this article.
March 14, 2019: Lancet Neurology
https://read.qxmd.com/read/30871944/global-regional-and-national-burden-of-stroke-1990-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#4
(no author information available yet)
BACKGROUND: Stroke is a leading cause of mortality and disability worldwide and the economic costs of treatment and post-stroke care are substantial. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic, comparable method of quantifying health loss by disease, age, sex, year, and location to provide information to health systems and policy makers on more than 300 causes of disease and injury, including stroke. The results presented here are the estimates of burden due to overall stroke and ischaemic and haemorrhagic stroke from GBD 2016...
March 11, 2019: Lancet Neurology
https://read.qxmd.com/read/30871943/the-global-burden-of-stroke-persistent-and-disabling
#5
Philip B Gorelick
No abstract text is available yet for this article.
March 11, 2019: Lancet Neurology
https://read.qxmd.com/read/30857949/management-of-epilepsy-in-women
#6
REVIEW
Linda J Stephen, Cynthia Harden, Torbjörn Tomson, Martin J Brodie
Epilepsy is a common neurological condition in women worldwide. Hormonal changes occurring throughout a woman's life can influence and be influenced by seizure mechanisms and antiepileptic drugs, presenting unique management challenges. Effective contraception is particularly important for women with epilepsy of childbearing potential because of antiepileptic drug-related teratogenicity and hormonal interactions; although studies reveal many women do not receive contraceptive and preconceptual counselling. Management challenges in this population include the higher risk of pregnancy complications and peripartum psychiatric problems than in women without epilepsy...
March 8, 2019: Lancet Neurology
https://read.qxmd.com/read/30846361/david-hafler-a-ceaseless-drive-to-solve-multiple-sclerosis
#7
Ruth Williams
No abstract text is available yet for this article.
March 4, 2019: Lancet Neurology
https://read.qxmd.com/read/30827690/franz-fazekas-a-specialist-in-not-overspecialising
#8
Adrian Burton
No abstract text is available yet for this article.
February 28, 2019: Lancet Neurology
https://read.qxmd.com/read/30803840/correction-to-lancet-neurol-2019-published-online-feb-15-http-dx-doi-org-10-1016-s1474-4422-19-30076-6
#9
(no author information available yet)
No abstract text is available yet for this article.
February 22, 2019: Lancet Neurology
https://read.qxmd.com/read/30803839/dispelling-myths-and-legends-about-dementia
#10
Peter Ranscombe
No abstract text is available yet for this article.
February 22, 2019: Lancet Neurology
https://read.qxmd.com/read/30797716/global-consequences-of-malignant-cns-tumours-a-call-to-action
#11
Lisa M DeAngelis
No abstract text is available yet for this article.
February 20, 2019: Lancet Neurology
https://read.qxmd.com/read/30797715/global-regional-and-national-burden-of-brain-and-other-cns-cancer-1990-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#12
(no author information available yet)
BACKGROUND: Brain and CNS cancers (collectively referred to as CNS cancers) are a source of mortality and morbidity for which diagnosis and treatment require extensive resource allocation and sophisticated diagnostic and therapeutic technology. Previous epidemiological studies are limited to specific geographical regions or time periods, making them difficult to compare on a global scale. In this analysis, we aimed to provide a comparable and comprehensive estimation of the global burden of brain cancer between 1990 and 2016...
February 20, 2019: Lancet Neurology
https://read.qxmd.com/read/30795988/fernando-cendes-targeting-epilepsy-by-improving-neuroimaging
#13
Tony Kirby
No abstract text is available yet for this article.
February 19, 2019: Lancet Neurology
https://read.qxmd.com/read/30795987/the-role-of-astroglia-in-alzheimer-s-disease-pathophysiology-and-clinical-implications
#14
REVIEW
Amaia M Arranz, Bart De Strooper
BACKGROUND: Astrocytes, also called astroglia, maintain homoeostasis of the brain by providing trophic and metabolic support to neurons. They recycle neurotransmitters, stimulate synaptogenesis and synaptic neurotransmission, form part of the blood-brain barrier, and regulate regional blood flow. Although astrocytes have been known to display morphological alterations in Alzheimer's disease for more than a century, research has remained neurocentric. Emerging evidence suggests that these morphological changes reflect functional alterations that affect disease...
February 19, 2019: Lancet Neurology
https://read.qxmd.com/read/30777657/intracerebral-haemorrhage-during-alemtuzumab-administration
#15
LETTER
Christina J Azevedo, Christen Kutz, Amy Dix, Aaron Boster, Nerses Sanossian, Jeffrey Kaplan
No abstract text is available yet for this article.
February 15, 2019: Lancet Neurology
https://read.qxmd.com/read/30773429/an-unparalleled-assessment-of-the-global-burden-of-epilepsy
#16
W Allen Hauser
No abstract text is available yet for this article.
February 14, 2019: Lancet Neurology
https://read.qxmd.com/read/30773428/global-regional-and-national-burden-of-epilepsy-1990-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#17
(no author information available yet)
BACKGROUND: Seizures and their consequences contribute to the burden of epilepsy because they can cause health loss (premature mortality and residual disability). Data on the burden of epilepsy are needed for health-care planning and resource allocation. The aim of this study was to quantify health loss due to epilepsy by age, sex, year, and location using data from the Global Burden of Diseases, Injuries, and Risk Factors Study. METHODS: We assessed the burden of epilepsy in 195 countries and territories from 1990 to 2016...
February 14, 2019: Lancet Neurology
https://read.qxmd.com/read/30738707/periprocedural-events-dominate-outcomes-of-carotid-stenting-and-endarterectomy
#18
J David Spence
No abstract text is available yet for this article.
February 6, 2019: Lancet Neurology
https://read.qxmd.com/read/30738706/long-term-outcomes-of-stenting-and-endarterectomy-for-symptomatic-carotid-stenosis-a-preplanned-pooled-analysis-of-individual-patient-data
#19
Thomas G Brott, David Calvet, George Howard, John Gregson, Ale Algra, Jean-Pierre Becquemin, Gert J de Borst, Richard Bulbulia, Hans-Henning Eckstein, Gustav Fraedrich, Jacoba P Greving, Alison Halliday, Jeroen Hendrikse, Olav Jansen, Jenifer H Voeks, Peter A Ringleb, Jean-Louis Mas, Martin M Brown, Leo H Bonati
BACKGROUND: The risk of periprocedural stroke or death is higher after carotid artery stenting (CAS) than carotid endarterectomy (CEA) for the treatment of symptomatic carotid stenosis. However, long-term outcomes have not been sufficiently assessed. We sought to combine individual patient-level data from the four major randomised controlled trials of CAS versus CEA for the treatment of symptomatic carotid stenosis to assess long-term outcomes. METHODS: We did a pooled analysis of individual patient-level data, acquired from the four largest randomised controlled trials assessing the relative efficacy of CAS and CEA for treatment of symptomatic carotid stenosis (Endarterectomy versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis trial, Stent-Protected Percutaneous Angioplasty of the Carotid Artery versus Endarterectomy trial, International Carotid Stenting Study, and Carotid Revascularization Endarterectomy versus Stenting Trial)...
February 6, 2019: Lancet Neurology
https://read.qxmd.com/read/30692053/thymectomy-in-myasthenia-gravis-when-why-and-how
#20
Sonia Berrih-Aknin, Rozen Le Panse
No abstract text is available yet for this article.
January 25, 2019: Lancet Neurology
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