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European Journal of Nuclear Medicine and Molecular Imaging

https://read.qxmd.com/read/36951992/-fuzzy-radiomics-the-way-forward-for-nuclear-medicine-imaging-applications
#1
EDITORIAL
Mathieu Hatt
No abstract text is available yet for this article.
March 23, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36951991/metabolic-patterns-on-18-f-fdg-pet-ct-in-patients-with-unresectable-stage-iii-nsclc-undergoing-chemoradiotherapy%C3%A2-%C3%A2-%C3%A2-durvalumab-maintenance-treatment
#2
JOURNAL ARTICLE
Adrien Holzgreve, Julian Taugner, Lukas Käsmann, Philipp Müller, Amanda Tufman, Niels Reinmuth, Minglun Li, Michael Winkelmann, Lena M Unterrainer, Alexander E Nieto, Peter Bartenstein, Wolfgang G Kunz, Jens Ricke, Claus Belka, Chukwuka Eze, Marcus Unterrainer, Farkhad Manapov
PURPOSE: In patients with unresectable stage III non-small-cell lung cancer (NSCLC), durvalumab maintenance treatment after chemoradiotherapy (CRT) significantly improves survival. So far, however, metabolic changes of tumoral lesions and secondary lymphoid organs under durvalumab are unknown. Hence, we assessed changes on [18 F]FDG PET/CT in comparison to patients undergoing CRT alone. METHODS: Forty-three patients with [18 F]FDG PET/CT both before and after standard CRT for unresectable stage III NSCLC were included, in 16/43 patients durvalumab maintenance treatment was initiated (CRT-IO) prior to the second PET/CT...
March 23, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36947186/angela-collarino-sergi-vidal-sicart-renato-a-vald%C3%A3-s%C3%A2-olmos-editors-nuclear-medicine-manual-on-gynaecological-cancers-and-other-female-malignancies-springer-nature-switzerland-ag-2022-isbn-978-3-031-05496-9
#3
JOURNAL ARTICLE
https://read.qxmd.com/read/36947185/optimisation-of-scan-duration-and-image-quality-in-oncological-89-zr-immunopet-imaging-using-the-biograph-vision-pet-ct
#4
JOURNAL ARTICLE
Joyce van Sluis, Ronald Boellaard, Rudi A J O Dierckx, Evelien L M van Esch, Demi A Croes, Laura Kist de Ruijter, Pim P van de Donk, Elisabeth G E de Vries, Walter Noordzij, Adrienne H Brouwers
PURPOSE: Monoclonal antibody (mAb)-based PET (immunoPET) imaging can characterise tumour lesions non-invasively. It may be a valuable tool to determine which patients may benefit from treatment with a specific monoclonal antibody (mAb) and evaluate treatment response. For 89 Zr immunoPET imaging, higher sensitivity of state-of-the art PET/CT systems equipped with silicon photomultiplier (SiPM)-based detector elements may be beneficial as the low positron abundance of 89 Zr causes a low signal-to-noise level...
March 22, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36944728/alberto-signore-editor-in-chief-nuclear-medicine-and-molecular-imaging-elsevier-2022-ebook-isbn-9780128229804-hardcover-isbn-9780128229606
#5
JOURNAL ARTICLE
Luigi Mansi
No abstract text is available yet for this article.
March 22, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36944727/abdelhamid-h-elgazzar-editor-the-pathophysiologic-basis-of-nuclear-medicine-fourth-edition-springer-nature-switzerland-ag-2015-2022-isbn-978-3-030-96251-7
#6
JOURNAL ARTICLE
Luigi Mansi
No abstract text is available yet for this article.
March 22, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36943430/pd-l1%C3%A2-%C3%A2-targeted-magnetic-fluorescent-hybrid-nanoparticles-illuminating-the-path-of-image-guided-cancer-immunotherapy
#7
EDITORIAL
Xiaoyan Li, Muhsin H Younis, Weijun Wei, Weibo Cai
No abstract text is available yet for this article.
March 21, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36933075/a-multi-label-cnn-model-for-the-automatic-detection-and-segmentation-of-gliomas-using-18-f-fet-pet-imaging
#8
JOURNAL ARTICLE
Masoomeh Rahimpour, Ronald Boellaard, Sander Jentjens, Wies Deckers, Karolien Goffin, Michel Koole
PURPOSE: The aim of this study was to develop a convolutional neural network (CNN) for the automatic detection and segmentation of gliomas using [18 F]fluoroethyl-L-tyrosine ([18 F]FET) PET. METHODS: Ninety-three patients (84 in-house/7 external) who underwent a 20-40-min static [18 F]FET PET scan were retrospectively included. Lesions and background regions were defined by two nuclear medicine physicians using the MIM software, such that delineations by one expert reader served as ground truth for training and testing the CNN model, while delineations by the second expert reader were used to evaluate inter-reader agreement...
March 18, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36933074/role-of-68-ga-ga-psma-11-pet-radiomics-to-predict-post-surgical-isup-grade-in-primary-prostate-cancer
#9
JOURNAL ARTICLE
Samuele Ghezzo, Paola Mapelli, Carolina Bezzi, Ana Maria Samanes Gajate, Giorgio Brembilla, Irene Gotuzzo, Tommaso Russo, Erik Preza, Vito Cucchiara, Naghia Ahmed, Ilaria Neri, Sofia Mongardi, Massimo Freschi, Alberto Briganti, Francesco De Cobelli, Luigi Gianolli, Paola Scifo, Maria Picchio
PURPOSE: The aim of this study is to investigate the role of [68 Ga]Ga-PSMA-11 PET radiomics for the prediction of post-surgical International Society of Urological Pathology (PS ISUP) grade in primary prostate cancer (PCa). METHODS: This retrospective study included 47 PCa patients who underwent [68 Ga]Ga-PSMA-11 PET at IRCCS San Raffaele Scientific Institute before radical prostatectomy. The whole prostate was manually contoured on PET images and 103 image biomarker standardization initiative (IBSI)-compliant radiomic features (RFs) were extracted...
March 18, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36929212/correction-to-clinical-prospective-study-of-gallium-68-68ga-labeled-fibroblast%C3%A2-activation-protein-inhibitor-pet-ct-in-the-diagnosis-of-biliary-tract-carcinoma
#10
Li Jinghua, Xu Kui, Guo Deliang, Liao Bo, Zhu Qian, Wang Haitao, Jiang Yaqun, Wu Dongde, Xia Xigang, Jiang Ping, Tang Shengli, Yang Zhiyong, He Yueming, Zhang Zhonglin, He Yong, Yuan Yufeng
No abstract text is available yet for this article.
March 17, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36929211/characterization-of-neuroinflammation-pattern-in-anti-lgi1-encephalitis-based-on-tspo-pet-and-symptom-clustering-analysis
#11
JOURNAL ARTICLE
Jingguo Wang, Jingjie Ge, Lei Jin, Bo Deng, Weijun Tang, Hai Yu, Xiang Zhang, Xiaoni Liu, Le Xue, Chuantao Zuo, Xiangjun Chen
PURPOSE: TSPO PET with radioligand [18 F]DPA-714 is an emerging molecular imaging technique that reflects cerebral inflammation and microglial activation, and it has been recently used in central nervous system diseases. In this study, we aimed to investigate the neuroinflammation pattern of anti-leucine-rich glioma-inactivated 1 (LGI1) protein autoimmune encephalitis (AIE) and to evaluate its possible correlation with clinical phenotypes. METHODS: Twenty patients with anti-LGI1 encephalitis from the autoimmune encephalitis cohort in Huashan Hospital and ten with other AIE and non-inflammatory diseases that underwent TSPO PET imaging were included in the current study...
March 17, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36929210/comparison-of-two-hybrid-sentinel-node-tracers-indocyanine-green-icg-99m-tc-nanocolloid-vs-icg-99m-tc-nanoscan-from-a-nuclear-medicine-and-surgical-perspective
#12
JOURNAL ARTICLE
Manon T A Vreeburg, Samaneh Azargoshasb, Danny van Willigen, Tom Molenaar, Matthias N van Oosterom, Tessa Buckle, Leon J Slof, Martin Klop, Baris Karakullukcu, Maarten Donswijk, Henk G van der Poel, Fijs W B van Leeuwen, Oscar R Brouwer, Daphne D D Rietbergen
BACKGROUND: Lymph node (LN) metastasis is a relevant predictor for survival in patients with a.o. penile cancer (PeCa), malignant melanoma. The sentinel node (SN) procedure comprises targeted resection of the first tumour-draining SNs. Here, the hybrid tracer indocyanine green (ICG)-99m Tc-nanocolloid has been used for several years to combine optical and nuclear detection. Recently, the resource of the nanocolloid precursor stopped production and the precursor was replaced by a different but chemically comparable colloid, nanoscan...
March 17, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36929181/radionuclide-based-theranostics-a-promising-strategy-for-lung-cancer
#13
REVIEW
Tianxing Zhu, Jessica C Hsu, Jingpei Guo, Weiyu Chen, Weibo Cai, Kai Wang
PURPOSE: This review aims to provide a comprehensive overview of the latest literature on personalized lung cancer management using different ligands and radionuclide-based tumor-targeting agents. BACKGROUND: Lung cancer is the leading cause of cancer-related deaths worldwide. Due to the heterogeneity of lung cancer, advances in precision medicine may enhance the disease management landscape. More recently, theranostics using the same molecule labeled with two different radionuclides for imaging and treatment has emerged as a promising strategy for systemic cancer management...
March 16, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36929180/development-of-psma-pet-guided-ct-based-radiomic-signature-to-predict-biochemical-recurrence-after-salvage-radiotherapy
#14
JOURNAL ARTICLE
Simon K B Spohn, Nina-Sophie Schmidt-Hegemann, Juri Ruf, Michael Mix, Matthias Benndorf, Fabian Bamberg, Marcus R Makowski, Simon Kirste, Alexander Rühle, Jerome Nouvel, Tanja Sprave, Marco M E Vogel, Polina Galitsnaya, Jürgen E Gschwend, Christian Gratzke, Christian Stief, Steffen Löck, Alex Zwanenburg, Christian Trapp, Denise Bernhardt, Stephan G Nekolla, Minglun Li, Claus Belka, Stephanie E Combs, Matthias Eiber, Lena Unterrainer, Marcus Unterrainer, Peter Bartenstein, Anca-L Grosu, Constantinos Zamboglou, Jan C Peeken
PURPOSE: To develop a CT-based radiomic signature to predict biochemical recurrence (BCR) in prostate cancer patients after sRT guided by positron-emission tomography targeting prostate-specific membrane antigen (PSMA-PET). MATERIAL AND METHODS: Consecutive patients, who underwent 68 Ga-PSMA11-PET/CT-guided sRT from three high-volume centers in Germany, were included in this retrospective multicenter study. Patients had PET-positive local recurrences and were treated with intensity-modulated sRT...
March 16, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36922449/machine-learning-radiomics-to-predict-the-early-recurrence-of-intrahepatic-cholangiocarcinoma-after-curative-resection-a-multicentre-cohort-study
#15
JOURNAL ARTICLE
Zhiyuan Bo, Bo Chen, Yi Yang, Fei Yao, Yicheng Mao, Jiangqiao Yao, Jinhuan Yang, Qikuan He, Zhengxiao Zhao, Xintong Shi, Jicai Chen, Zhengping Yu, Yunjun Yang, Yi Wang, Gang Chen
PURPOSE: Postoperative early recurrence (ER) leads to a poor prognosis for intrahepatic cholangiocarcinoma (ICC). We aimed to develop machine learning (ML) radiomics models to predict ER in ICC after curative resection. METHODS: Patients with ICC undergoing curative surgery from three institutions were retrospectively recruited and assigned to training and external validation cohorts. Preoperative arterial and venous phase contrast-enhanced computed tomography (CECT) images were acquired and segmented...
March 16, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36922448/collection-on-clinical-total-body-pet-studies
#16
EDITORIAL
Riemer H J A Slart, Axel Rominger
No abstract text is available yet for this article.
March 16, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36920494/the-diagnostic-performance-of-functional-dopaminergic-scintigraphic-imaging-in-the-diagnosis-of-dementia-with-lewy-bodies-an-updated-systematic-review
#17
REVIEW
Mario Jreige, George K Kurian, Jérémy Perriraz, Jevita Potheegadoo, Fosco Bernasconi, Sara Stampacchia, Olaf Blanke, Griffa Alessandra, Noemie Lejay, Paolo Salvioni Chiabotti, Olivier Rouaud, Marie Nicod Lalonde, Niklaus Schaefer, Giorgio Treglia, Gilles Allali, John O Prior
INTRODUCTION: Dopaminergic scintigraphic imaging is a cornerstone to support the diagnosis in dementia with Lewy bodies. To clarify the current state of knowledge on this imaging modality and its impact on clinical diagnosis, we performed an updated systematic review of the literature. METHODS: This systematic review was carried out according to PRISMA guidelines. A comprehensive computer literature search of PubMed/MEDLINE, EMBASE, and Cochrane Library databases for studies published through June 2022 was performed using the following search algorithm: (a) "Lewy body" [TI] OR "Lewy bodies" [TI] and (b) ("DaTscan" OR "ioflupane" OR "123ip" OR "123?ip" OR "123 ip" OR "123i-FP-CIT" OR "FPCIT" OR "FP-CIT" OR "beta?CIT" OR "beta CIT" OR "CIT?SPECT" OR "CIT SPECT" OR "Dat?scan*" OR "dat scan*" OR "dat?spect*" OR "SPECT")...
March 15, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36914753/identification-of-a-ceacam5-targeted-nanobody-for-positron-emission-tomography-imaging-and-near-infrared-fluorescence-imaging-of-colorectal-cancer
#18
JOURNAL ARTICLE
Yitai Xiao, Chaoming Mei, Duo Xu, Fan Yang, Meilin Yang, Lei Bi, Junjie Mao, Pengfei Pang, Dan Li
PURPOSE: Here, we aim to identify a CEACAM5-targeted nanobody and demonstrate its application in positron emission tomography (PET) imaging and near-infrared (NIR) fluorescence imaging in colorectal cancer (CRC). METHODS: Immunohistochemistry was applied to verify CEACAM5 expression in CRC and metastatic lymph nodes (mLNs). CEACAM5-targeted nanobodies were obtained by immunization of human CEACAM5 protein in a dromedary, followed by several rounds of phage screenings...
March 14, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36907901/rabbit-fever-granulomatous-inflammation-by-francisella-tularensis-mimics-lung-cancer-in-dual-tracer-18-fdg-and-68-ga-fapi-pet-ct
#19
JOURNAL ARTICLE
Mathias Meetschen, Patrick Sandach, Kaid Darwiche, Dirk Theegarten, Annette Moter, Benedikt Michael Schaarschmidt, Ken Herrmann, Wolfgang P Fendler, Hubertus Hautzel, Marcel Opitz
No abstract text is available yet for this article.
March 13, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/36905412/prospective-validation-of-tumor-folate-receptor-expression-density-with-the-association-of-pafolacianine-fluorescence-during-intraoperative-molecular-imaging-guided-lung-cancer-resections
#20
JOURNAL ARTICLE
Feredun Azari, Kevin Zhang, Gregory Kennedy, Patrick Bou-Samra, Ashley Chang, Bilal Nadeem, Austin Chang, Aysuna Galandarova, Arturan Ibrahimli, Ziya Karimov, Azra Din, John Kucharczuk, Jarrar Doraid, Taine Pechet, Edward Delikatny, Sunil Singhal
PURPOSE: Pafolacianine, a folate receptor alpha-targeted NIR tracer, has demonstrated clear efficacy in intraoperative molecular imaging-guided (IMI) lung cancer surgery. However, the selection of patients who would benefit from IMI remains challenging given the variability of fluorescence with patient-associated and histopathologic factors. Our goal in this study was to prospectively evaluate whether preoperative FRα/FRβ staining can predict pafolacianine-based fluorescence during real-time lung cancer resections...
March 11, 2023: European Journal of Nuclear Medicine and Molecular Imaging
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