Simon K B Spohn, Nina-Sophie Schmidt-Hegemann, Juri Ruf, Michael Mix, Matthias Benndorf, Fabian Bamberg, Marcus R Makowski, Simon Kirste, Alexander Rühle, Jerome Nouvel, Tanja Sprave, Marco M E Vogel, Polina Galitsnaya, Jürgen E Gschwend, Christian Gratzke, Christian Stief, Steffen Löck, Alex Zwanenburg, Christian Trapp, Denise Bernhardt, Stephan G Nekolla, Minglun Li, Claus Belka, Stephanie E Combs, Matthias Eiber, Lena Unterrainer, Marcus Unterrainer, Peter Bartenstein, Anca-L Grosu, Constantinos Zamboglou, Jan C Peeken
PURPOSE: To develop a CT-based radiomic signature to predict biochemical recurrence (BCR) in prostate cancer patients after sRT guided by positron-emission tomography targeting prostate-specific membrane antigen (PSMA-PET). MATERIAL AND METHODS: Consecutive patients, who underwent 68 Ga-PSMA11-PET/CT-guided sRT from three high-volume centers in Germany, were included in this retrospective multicenter study. Patients had PET-positive local recurrences and were treated with intensity-modulated sRT...
March 16, 2023: European Journal of Nuclear Medicine and Molecular Imaging