Ross I Donaldson, Jonathan K Armstrong, Oliver J Buchanan, Todd L Graham, John S Cambridge, Nely N Cristerna, Diane Goldenberg, Captain David A Tanen, Timothy C Fisher, Juliana Tolles, Christopher J Burns, James D Ross
BACKGROUND: This study compared a novel topical hydrogel burn dressing (CI-PRJ012) to standard of care (silver sulfadiazine) and to untreated control in a swine thermal burn model, to assess for wound healing properties both in the presence and absence of concomitant bacterial inoculation. METHODS: Eight equal burn wounds were created on six Yorkshire swine. Half the wounds were randomized to post-burn bacterial inoculation. Wounds were subsequently randomized to three treatments groups: no intervention, CI-PRJ012, or silver sulfadiazine cream...
March 15, 2024: Burns