journal
https://read.qxmd.com/read/38538444/self-harm-in-burn-patients-an-analysis-of-finnish-patient-records-2011-2020
#1
JOURNAL ARTICLE
Lotta Purola, Jyrki Vuola, Raimo Palmu
AIM: To collect data on self-harm burn patients at a national level in Finland and analyze patient characteristics. MATERIAL AND METHODS: First, we went through The National Care Register for Health Care (Hilmo) records from 2011 to 2015 to find all patients in Finland with both burn and self-harm ICD10 codes. Then we investigated the medical records of all patients treated at the National Burn Centre (NBC) in Helsinki in the period 2011-2020. Patients admitted to the hospital because of self-harm burn injuries were compared to those without self-harm injuries...
March 15, 2024: Burns
https://read.qxmd.com/read/38494396/subtherapeutic-beta-lactam-plasma-concentrations-in-critically-ill-burned-patients-in-the-era-of-continuous-intravenous-administration
#2
LETTER
Germain Duputié, François Darrouzain, Nathalie Forme, Benjamin Cohen, Francis Rémérand, Romain Miguel Montanes
No abstract text is available yet for this article.
March 8, 2024: Burns
https://read.qxmd.com/read/38492980/the-impact-of-different-co-morbidities-on-clinical-outcomes-and-resource-utilization-in-critically-ill-burn-and-surgical-patients-a-population-based-analysis-of-social-determinants-of-health
#3
JOURNAL ARTICLE
Tomer Lagziel, Luis H Quiroga, Emily Ross, Kimberly H Khoo, Feras Shamoun, Mohammed Asif, Julie A Caffrey, C Scott Hultman
BACKGROUND: This study aims to establish the significance of social determinants of health and prevalent co-morbidities on multiple indicators for quality of care in patients admitted to the Burn and Surgical Intensive Care Unit (ICU). METHODS: We performed a retrospective analysis of population group data for patients admitted at the Burn and Surgical ICU from January 1, 2016, to November 18, 2019. The primary outcomes were length of hospital stay (LOS), mortality, 30-day readmission, and hospital charges...
March 8, 2024: Burns
https://read.qxmd.com/read/38503573/patients-with-hypertrophic-scars-following-severe-burn-injury-express-different-long-noncoding-rnas
#4
JOURNAL ARTICLE
Ping Zhou, Yan Jiang, Ao-Ya Liu, Xu-Lin Chen, Fei Wang
OBJECTIVE: Research indicates that long noncoding RNAs (lncRNAs) contribute significantly to fibrotic diseases. Although lncRNAs may play a role in hypertrophic scars after burns, its mechanisms remain poorly understood. METHODS: Using chip technology, we compared the lncRNA expression profiles of burn patients and healthy controls (HCs). Microarray results were examined by quantitative reverse-transcription polymerase chain reaction (RT-PCR) to verify their reliability...
March 7, 2024: Burns
https://read.qxmd.com/read/38492982/an-artificial-intelligence-language-model-improves-readability-of-burns-first-aid-information
#5
JOURNAL ARTICLE
Alexander J Baldwin
AIMS: This study aimed to assess the potential of using an artificial intelligence (AI) large language model to improve the readability of burns first aid information. METHODS: An AI language model (ChatGPT-3) was used to rewrite content from the top 50 English-language webpages containing burns first aid information to be understandable by an individual with the literacy level of an 11-year-old, as recommended by the American Medical Association and Health Education England...
March 7, 2024: Burns
https://read.qxmd.com/read/38503574/associations-between-burn-care-services-and-impairment-at-discharge-after-burn-injury-analysis-of-the-global-burn-registry
#6
JOURNAL ARTICLE
Ingrid Parry, Janice Bell
BACKGROUND: Throughout the world, burn injury is a major cause of death and disability. In resource-limited countries, burn injury is one of the leading causes of permanent disability among children who survive traumatic injuries, and burn injury is the fourth leading cause of disability worldwide. This study applied Andersen's model of health care access to evaluate if patient characteristics (predisposing factors), burn care service availability (enabling factors) and injury characteristics (need) are associated with physical impairment at hospital discharge for patients surviving burn injuries globally...
March 6, 2024: Burns
https://read.qxmd.com/read/38492983/inhibition-of-keloid-fibroblast-proliferation-by-artesunate-is-mediated-by-targeting-the-ire1%C3%AE-xbp1-signaling-pathway-and-decreasing-tgf-%C3%AE-1
#7
JOURNAL ARTICLE
Xiaomei Han, Shaoqian Jiang, Caixia Hu, Ying Wang, Lu Zhao, Wenqing Wang
BACKGROUND: Keloid is a benign hyperplastic dermatosis with high recurrence rate and complex pathogenesis. There is no universally effective treatment yet. New therapies and elucidation of pathogenesis are urgently required. AIMS: To explore the function of IRE1α/XBP1 in keloid fibroblasts and to investigate the potential mechanism of artesunate in inhibiting keloid hyperplasia. METHODS: Human keloid fibroblasts (KFs) were cultured, and the expressions of XBP1 and TGF-β1 were detected by immunohistochemistry...
March 5, 2024: Burns
https://read.qxmd.com/read/38490836/models-predicting-mortality-risk-of-patients-with-burns-to-%C3%A2-%C3%A2-50-of-the-total-body-surface
#8
JOURNAL ARTICLE
Yiran Wang, Chenghao Cai, Zhikang Zhu, Deqing Duan, Wanting Xu, Tao Shen, Xingang Wang, Qinglian Xu, Hongyan Zhang, Chunmao Han
BACKGROUND: Several models predicting mortality risk of burn patients have been proposed. However, models that consider all such patients may not well predict the mortality of patients with extensive burns. METHOD: This retrospective multicentre study recruited patients with extensive burns (≥ 50% of the total body surface area [TBSA]) treated in three hospitals of Eastern China from 1 January 2016 to 30 June 2022. The performances of six predictive models were assessed by drawing receiver operating characteristic (ROC) and calibration curves...
March 4, 2024: Burns
https://read.qxmd.com/read/38519375/risks-of-mental-disorders-among-inpatients-with-burn-injury-a-nationwide-cohort-study
#9
JOURNAL ARTICLE
Fan Peng, Chi-Hsiang Chung, Wan-Ying Koh, Wu-Chien Chien, Ching-En Lin
OBJECTIVE: This investigation identified the association between burn injuries and the risk of mental disorders in patients with no documented pre-existing psychiatric comorbidities. We also examined the relationship of injury severity and the types of injury with the likelihood of receiving new diagnoses of mental disorders. METHODS: This population-based retrospective cohort study used administrative data extracted from the Taiwanese National Health Insurance Research Database (NHIRD) between 2000 and 2013...
March 2, 2024: Burns
https://read.qxmd.com/read/38494394/relationship-between-quality-of-life-emotional-symptomology-and-perceived-emotional-intelligence-in-a-sample-of-burn-victims
#10
JOURNAL ARTICLE
A Silva, J Marzo, J A García Del Castillo
The main objective of this study is to analyse the association between Quality of Life (QOL), Emotional Symptomology and perceived Emotional Intelligence (EI) in burn patients. Additionally, it is intended determine the predictor models of QOL, and confirm the mediating effect of emotional symptomology between QOL and perceived EI. This is a transversal study developed in the Hospital da Prelada, Porto, Portugal, with a sample of 92 patients that were hospitalized in the Burn Unit and the Reconstructive Plastic Surgery Service...
March 2, 2024: Burns
https://read.qxmd.com/read/38494397/the-incidence-of-cancer-following-hospitalisation-for-a-burn-injury-in-scotland-2009-2019-a-retrospective-cohort-study
#11
JOURNAL ARTICLE
Sai Phani Maddipatla, Philip McLoone, Kathryn Puxty, Christopher McGovern
BACKGROUND: Studies suggest increased occurrence of cancer in persons who have experienced a burn injury with hospital admission. OBJECTIVE: To determine the incidence of cancer among those hospitalised for burn injuries in Scotland compared with a similar group without a history of burn injury hospitalisation. METHOD: A retrospective cohort design was used to compare cancer (ICD10 C00-97, excluding C44) incidence in two groups: 6805 burn injury patients discharged from Scottish hospitals between 2009 and 2019, and 25,946 subjects from the general population who were matched to burn patients by sex, year of birth, and degree of social deprivation...
March 1, 2024: Burns
https://read.qxmd.com/read/38494395/cytosorb%C3%A2-in-burn-patients-with-septic-shock-and-acute-kidney-injury-on-continuous-kidney-replacement-therapy-is-associated-with-improved-clinical-outcome-and-survival
#12
JOURNAL ARTICLE
Filippo Mariano, Domenico Greco', Nadia Depetris, Alberto Mella, Alberto Sciarrillo, Maurizio Stella, Maurizio Berardino, Daniela Risso, Roberto Gambino, Luigi Biancone
BACKGROUND: In burn patients, septic shock and acute kidney injury (AKI) with use of continuous renal replacement therapy (CRRT) severely increase morbidity and mortality. Sorbent therapies could be an adjunctive therapy to address the underlying metabolic changes in inflammatory and anti-inflammatory cytokines dysregulated production. METHODS: A retrospectively observational study of 35 severe burn patients admitted to the Burn Center (Turin, Italy, from January 2017 to December 2022), who underwent CRRT for AKI-associated septic shock...
March 1, 2024: Burns
https://read.qxmd.com/read/38492979/a-national-analysis-of-burn-injuries-among-homeless-persons-presenting-to-emergency-departments
#13
JOURNAL ARTICLE
Jennifer K Shah, Farrah Liu, Priscila Cevallos, Uchechukwu O Amakiri, Thomas Johnstone, Rahim Nazerali, Clifford C Sheckter
INTRODUCTION: Burn injuries among the homeless are increasing as record numbers of people are unsheltered and resort to unsafe heating practices. This study characterizes burns in homeless encounters presenting to US emergency departments (EDs). METHODS: Burn encounters in the 2019 Nationwide Emergency Department Sample (NEDS) were queried. ICD-10 and CPT codes identified homelessness, injury regions, depths, total body surface area (TBSA %), and treatment plans...
March 1, 2024: Burns
https://read.qxmd.com/read/38490838/inflammatory-proteins-and-neutrophil-extracellular-traps-increase-in-burn-blister-fluid-24h-after-burn
#14
JOURNAL ARTICLE
Tuo Zang, Mark W Fear, Tony J Parker, Andrew J A Holland, Lisa Martin, Donna Langley, Roy Kimble, Fiona M Wood, Leila Cuttle
Burn wound blister fluid is a valuable matrix for understanding the biological pathways associated with burn injury. In this study, 152 blister fluid samples collected from paediatric burn wounds at three different hospitals were analysed using mass spectrometry proteomic techniques. The protein abundance profile at different days after burn indicated more proteins were associated with cellular damage/repair in the first 24 h, whereas after this point more proteins were associated with antimicrobial defence...
March 1, 2024: Burns
https://read.qxmd.com/read/38490834/efficacy-of-hydrosurgical-eschar-excision-following-meek-microskin-grafting-in-patients-with-massive-burns-a-retrospective-study-of-a-single-center
#15
JOURNAL ARTICLE
Yan Jiang, Ping Zhou, Ao-Ya Liu, Sheng Liu, Xu-Lin Chen, Fei Wang
INTRODUCTION: One of the most common traumatic injuries, burn injuries lead to at least 180,000 deaths each year worldwide. Massive burns result in severe tissue loss and increase the rate of infection. Eschar excision with skin grafting is the gold standard of treatments for massive burns. Retaining dermis tissue is the key to ensuring the survival of skin grafts and rapidly closing exposed tissues. Traditional eschar excision with Humby or Weck knife controls the depth of excision until the dermis, but ensuring the accuracy of excision is challenging...
March 1, 2024: Burns
https://read.qxmd.com/read/38472000/multi-resistant-organisms-in-burn-patients-an-end-or-a-new-beginning
#16
REVIEW
Ahmed Hagiga, Baljit Dheansa
Infections are a major cause of morbidity and mortality in burn patients, and the rise of multidrug-resistant organisms (MDROs) has made it more challenging to manage and prevent infections. This review examines the available treatment options for MDROs in burn patients and anticipates the future challenges posed by their increasing prevalence. The review covers new antibiotics, such as Eravacycline and Plazomicin, as well as non-antibiotic therapies, such as bacteriophages and nanoparticles. Future research should focus on examining the long-term efficacy, cost-effectiveness, and in vivo efficacy of different treatment modalities...
March 1, 2024: Burns
https://read.qxmd.com/read/38472006/implementation-of-a-geriatric-care-bundle-for-older-adults-with-acute-burns
#17
JOURNAL ARTICLE
Julia Oehlers, Carolyn Blayney, Jo Tate, Alexander Cheng, Andrew Tucker, May J Reed, Barclay T Stewart, Saman Arbabi, Kathleen O'Connell, Elisabeth Powelson, Tam N Pham
BACKGROUND: Frailty and comorbidities are important outcome determinants in older patients (age ≥65) with burns. A Geriatric Burn Bundle (Geri-B) was implemented in 2019 at a regional burn center to standardize care for older adults. Components included frailty screening and protocolized geriatric co-management, malnutrition screening with nutritional support, and geriatric-centered pain regimens. METHODS: This study aimed to qualitatively evaluate the implementation of Geri-B using the Proctor Framework...
February 29, 2024: Burns
https://read.qxmd.com/read/38458960/impacts-of-intelligent-monitoring-technology-installation-and-additional-modalities-on-hand-hygiene-compliance-in-a-burn-center-a-quasi-experimental-longitudinal-trial
#18
JOURNAL ARTICLE
Kayhan Gurbuz, Koray Das, Mete Demir, Bedia Mutay Suntur, Ozer Ozlu, Abdulkadir Basaran, Merve Kilic Cil, Abdullah Golbol
BACKGROUND: The increasing development of intelligent technologies for hand hygiene (HH) compliance audit has the potential to create an alternative to direct observation (DO), which is still considered the gold standard but has disadvantages such as lack of standardized monitoring practices, Hawthorne effect, insufficient sample size, and time/resource consumption. We aimed to share our preliminary results on the impacts of intelligent monitoring technology installation (IMTI) and additional modalities on healthcare workers' (HCWs') HH compliance in a Burn Center, according to the "5 Moments of HH" concept defined by the World Health Organization (WHO)...
February 29, 2024: Burns
https://read.qxmd.com/read/38490837/virtual-burn-care-friend-or-foe-a-systematic-review
#19
REVIEW
Eli Mondor, Jaymie Barnabe, Ella Marie Robyn Laguan, Claudia Malic
INTRODUCTION: Evidence on the impact of virtual care for patients with burn injuries is variable. This review aims to evaluate its use in remote assessment, rounding, and follow-up through outcomes of efficacy, usability, costs, satisfaction, clinical outcomes, impacts on triage and other benefits/drawbacks. METHODS: A PRISMA-compliant qualitative systematic review (PROSPERO CRD42021267787) was conducted in four databases and the grey literature for primary research published between 01/01/2010 and 12/31/2020...
February 28, 2024: Burns
https://read.qxmd.com/read/38490835/barriers-and-prospects-for-skin-grafting-in-burn-treatment-across-african-countries
#20
JOURNAL ARTICLE
Dorothy Bbaale, Christoph Mohr, Judith Lindert, Nikki Allorto, Tresor Mabanza, Jean Bosco Katabogama, Shobha Chamania, Richard Elrod, Michael Boettcher, Julia Elrod
INTRODUCTION: The current standard management of full-thickness or deep dermal burns is early tangential excision and skin grafting. A conservative approach to deep burns without the option of skin grafting results in delayed wound healing, possibly leading to wound infection and is associated with hypertrophic scarring and increased morbidity and mortality. The aim of this study was to improve the understanding of the management and availability to perform skin grafting for burns on the African continent...
February 28, 2024: Burns
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