journal
https://read.qxmd.com/read/36965840/most-common-ophthalmic-diagnoses-in-eye-emergency-departments-a-multicenter-study
#1
JOURNAL ARTICLE
Heba Mahjoub, Joseph Ssekasanvu, Yoshihiro Yonekawa, Grant A Justin, Kara M Cavuoto, Alice Lorch, Vrinda Madan, Ishwarya Sivakumar, Xiyu Zhao, Michael Quintero, Olivia Febles Simeon, Mirataollah Salabati, Connie M Wu, Fasika A Woreta
PURPOSE: To characterize the most common ophthalmic conditions seen in the emergency department (ED) DESIGN: Cross-sectional study METHODS: Multicenter study of 64988 patients who visited the Bascom Palmer Eye Institute, Massachusetts Eye and Ear, Wills Eye Hospital, Johns Hopkins Hospital/Wilmer Eye Institute from January 1st , 2019 until December 31st , 2019. Demographic and primary diagnosis data was extracted including gender, age, race, ethnicity, insurance type, and ophthalmology consult status...
March 23, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36963606/the-impact-of-social-determinants-of-health-on-vision-loss-from-cataracts-and-cataract-surgery-utilization-in-the-united-states-analysis-of-three-national-health-interview-survey-years-2008-2016-2017
#2
JOURNAL ARTICLE
Abdelhalim A Awidi, Jiangxia Wang, Varshini Varadaraj, Muhammad Ali, Cindy X Cai, Alfred Sommer, Pradeep Y Ramulu, Fasika A Woreta
PURPOSE: To investigate the association of social determinants of health (SDOH) factors and cataract-related outcomes disparities. DESIGN: Cross-sectional, with a nationally representative sample. METHODS: We used publicly available data from the 2008, 2016, and 2017 National Health Interview Survey datasets. Outcome measures included self-reported prevalence for ever been diagnosed with cataract, vision loss secondary to cataracts, and likelihood of undergoing cataract surgery...
March 22, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36963605/motion-tracking-brillouin-microscopy-evaluation-of-normal-keratoconic-and-post-laser-vision-correction-corneas-motion-tracking-brillouin-microscopy-in-keratoconus-and-laser-vision-correction
#3
JOURNAL ARTICLE
Hongyuan Zhang, Lara Asroui, Imane Tarib, William J Dupps, Giuliano Scarcelli, J Bradley Randleman
PURPOSE: To characterize focal biomechanical differences between normal, keratoconic, and post-laser vision correction corneas using motion tracking Brillouin microscopy. DESIGN: Prospective cross-sectional study METHODS: Thirty eyes from 30 patients (10 normal controls (Controls), 10 post-laser vision correction (LVC), 10 stage I or II keratoconus (KC)) had Scheimpflug and motion tracking Brillouin microscopy imaging using a custom-built device. Mean, Maximum (Max), and Minimum (Min) Brillouin shift, Spatial standard deviation (SSD), and Max-Min values were compared...
March 22, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36963604/multimodal-imaging-characteristics-and-risk-factors-analysis-of-waldenstr%C3%A3-m-macroglobulinemia-retinopathy-risk-factors-of-waldenstr%C3%A3-m-macroglobulinemia-retinopathy
#4
JOURNAL ARTICLE
Huan Chen, Yuelin Wang, Zhengbo Xu, Donghui Li, Hong Du, Youxin Chen, Jun Feng
PURPOSE: To summarize the multimodal imaging features and analyze the risk factors of Waldenström macroglobulinemia retinopathy (WMR). DESIGN: Retrospective, cross-sectional study. METHODS: Patients diagnosed with Waldenström macroglobulinemia and underwent ophthalmic examination in Peking Union Medical College Hospital in the last decade were included. Multimodal imaging characteristics of WMR were summarized. Univariate and multivariate logistic regression analysis of WMR and potential systemic and ocular factors was performed...
March 22, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36963603/race-distribution-in-non-arteritic-anterior-ischemic-optic-neuropathy
#5
JOURNAL ARTICLE
Ana Banc, Mark Kupersmith, Nancy J Newman, Valérie Biousse
PURPOSE: To describe the racial distribution of patients diagnosed with non-arteritic anterior ischemic optic neuropathy (NAION) in two large urban academic centers in the United States (US). DESIGN: Retrospective cross-sectional study. METHODS: All NAION patients evaluated between 2014 and 2022 in tertiary neuro-ophthalmology services in Atlanta, GA and New York, NY, respectively, were included. In order to assess the racial accessibility to our services, similar numbers of idiopathic intracranial hypertension (IIH) patients seen in the same services were included...
March 22, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36963602/endogenous-endophthalmitis-from-a-klebsiella-pneumoniae-liver-abscess-the-incidence-risk-factors-and-utility-of-imaging
#6
JOURNAL ARTICLE
Eunah Kim, Iksoo Byon, Jae Jung Lee, Young Mi Seol, Han Jo Kwon, Sung Who Park, Ji Eun Lee
PURPOSE: We investigated the rate of ophthalmologic examinations to detect endogenous endophthalmitis in patients with pyogenic liver abscesses (PLAs) and the incidence and risk factors of endophthalmitis from a PLA caused by Klebsiella pneumoniae (PLA-K). DESIGN: A retrospective case series METHODS: A total of 536 patients admitted to a university hospital in Korea, to treat PLAs during 2012-2022 were primarily included. The proportion of patients who were referred for ophthalmologic examinations was investigated and the incidence of endophthalmitis in 248 patients with PLA-K was calculated...
March 22, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36963601/binocular-visual-outcomes-comparison-of-two-trifocal-intraocular-lenses-in-high-myopic-cataract-patients-a-1-year-multicenter-study-comparison-of-two-trifocal-iols-in-high-myopic-cataracts
#7
JOURNAL ARTICLE
Jiying Shen, Lei Cai, Baoxian Zhuo, Adilamu Abulimiti, Shuang Ni, Limei Zhang, Haike Guo, Xu Chen, Jin Yang
PURPOSE: To compare the postoperative visual outcomes and quality of vision obtained with two types of diffractive trifocal intraocular lenses (IOLs) in patients with high-myopic cataracts. DESIGN: Prospective, multi-center, randomized controlled trial. METHODS: Patients with high-myopic cataracts were randomized to binocular implantation of either the TFNT00 (n = 27) or the 839MP (n = 28) trifocal IOLs at three surgery centers in China and were followed-up for 1 year...
March 22, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36963600/longitudinal-analysis-of-ocular-manifestation-and-interleukin-during-intravitreal-treatment-of-vitreoretinal-lymphoma-with-methotrexate
#8
JOURNAL ARTICLE
Junxiang Gu, Tingting Jiang, Shixue Liu, Xiuju Chen, Zhujian Wang, Peijun Zhang, Ling Wang, Rui Jiang, Xin Huang, Gezhi Xu, Qing Chang
PURPOSE: To explore the trend of ocular manifestations and interleukin (IL) during the treatment of vitreoretinal lymphoma (VRL), and to evaluate potential effects of different intravitreal administration schedules on the therapeutic response. DESIGN: Interventional comparative non-randomized clinical study. METHODS: Patients diagnosed with VRL from January 2011 to January 2022 were included. Intravitreal methotrexate (MTX) injections consisting induction, consolidation and maintenance were scheduled...
March 22, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36958537/onset-and-progression-of-persistent-choroidal-hypertransmission-defects-in-intermediate-amd-a-novel-clinical-trial-endpoint-hypertransmission-defects-as-a-clinical-trial-endpoint
#9
JOURNAL ARTICLE
Jeremy Liu, Mengxi Shen, Rita Laiginhas, Gissel Herrera, Jianqing Li, Yingying Shi, Farhan Hiya, Omer Trivizki, Nadia K Waheed, Carol Y Chung, Eric M Moult, James G Fujimoto, Giovanni Gregori, Philip J Rosenfeld
PURPOSE: The appearance and growth of persistent choroidal hypertransmission defects (hyperTDs) detected on en face swept-source OCT (SS-OCT) images from eyes with intermediate AMD (iAMD) were studied to determine if they could serve as novel clinical trial endpoints. DESIGN: Post-hoc subgroup analysis of a prospective study. METHODS: Subjects with iAMD underwent 6 × 6 mm SS-OCT angiography (SS-OCTA) imaging at their baseline and follow-up visits...
March 21, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36948373/change-in-cone-structure-over-24-months-in-ush2a-related-retinal-degeneration
#10
JOURNAL ARTICLE
Jacque L Duncan, Wendi Liang, Maureen G Maguire, Travis C Porco, Jessica Wong, Isabelle Audo, Jenna A Cava, Kate Grieve, Angelos Kalitzeos, Joseph Kreis, Michel Michaelides, Nathaniel Norberg, Michel Paques, Joseph Carroll
PURPOSE: To describe cone structure changes using adaptive optics scanning laser ophthalmoscopy (AOSLO) in the Rate of Progression of USH2A-related Retinal Degeneration (RUSH2A) study. METHODS: AOSLO images were acquired at 4 centers, twice at baseline and annually for 24 months in this natural history study. For each eye, at least 10 regions of interest (ROIs) with ≥ 50 contiguous cones were analyzed by masked, independent graders. Cone spacing Z-scores, standard deviations from the normal mean at the measured location, were compared between graders and tests at baseline...
March 20, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36948372/nov03-for-signs-and-symptoms-of-dry-eye-disease-associated-with-meibomian-gland-dysfunction-the-randomized-phase-3-mojave-study-nov03-for-dry-eye-disease-associated-with-meibomian-gland-dysfunction-69-characters-limit-60
#11
JOURNAL ARTICLE
John D Sheppard, Fred Kurata, Alice T Epitropoulos, Sonja Krösser, Jason L Vittitow
PURPOSE: To evaluate the efficacy and safety of NOV03 (perfluorohexyloctane) ophthalmic drop for the treatment of signs and symptoms of dry eye disease (DED) associated with meibomian gland dysfunction (MGD). DESIGN: Randomized, double-masked, controlled trial. METHODS: Patients aged ≥18 years with a history of DED and signs of MGD were randomly assigned 1:1 to treatment with NOV03 or hypotonic saline (0.6%) 4 times daily for 8 weeks...
March 20, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36948371/morphometric-assessment-of-the-ciliary-body-in-patients-with-marfan-syndrome-and-ectopia-lentis-a-quantitative-study-using-ultrasound-biomicroscopy-ciliary-body-morphology-in-marfan-syndrome-and-ectopia-lentis
#12
JOURNAL ARTICLE
Wan-Nan Jia, Qian-Yi Wang, Ling-Ling Niu, Ze-Xu Chen, Yong-Xiang Jiang
PURPOSE: To explore the biometric characteristics of the ciliary body in patients with Marfan syndrome (MFS) and ectopia lentis (EL). DESIGN: Cross-sectional study. METHODS: Seventy-two consecutive MFS patients with EL and 72 non-disease controls were recruited. Ciliary body biometric parameters such as ciliary muscle cross-sectional area at 2000 μm from the scleral spur (CMA2000), ciliary muscle thickness at 1000 μm from the scleral spur (CMT1000), and maximum ciliary body thickness (CBTmax) were measured from multiple directions with ultrasound biomicroscopy (UBM)...
March 20, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36934958/short-term-outcomes-of-modified-boston-type-ii-keratoprosthesis-implantation-with-autologous-auricular-cartilage-reinforcement-outcomes-of-modified-boston-type-ii-keratoprosthesis
#13
JOURNAL ARTICLE
Mimi Liu, Han Wen, Lei Lin, Chaoxiang Ge, Lili Guo, James Chodosh, Qinxiang Zheng, Wei Chen
PURPOSE: To report the short-term visual outcomes and complications of a modified Boston Type-II keratoprosthesis (Kpro) procedure. DESIGN: Retrospective case series. METHODS: 37 eyes of 37 patients who had an implantation of autologous auricular cartilage reinforced (AACR)-Boston Type-II Kpro (BK2) were included in the current study. Preoperative and postoperative data were recorded and analyzed for each eye. MAIN OUTCOME MEASURES: Best-corrected visual acuity (BCVA), symptoms as assessed by questionnaires, complications associated with implantation, and retention of the implanted BK2 device...
March 17, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36933856/retinopathy-of-prematurity-outcomes-of-neonates-meeting-only-a-single-screening-criterion-proposal-of-the-two-rop-algorithm-single-screening-criterion-for-retinopathy-of-prematurity
#14
JOURNAL ARTICLE
Nimesh A Patel, Sandra Hoyek, Hasenin Al-Khersan, Kenneth C Fan, Nicolas A Yannuzzi, Jose Davila, Audina M Berrocal
PURPOSE: To assess the rates of retinopathy of prematurity (ROP) and treatment-warranted ROP in a modern set of patients meeting zero or one of the current ROP screening criteria. DESIGN: Retrospective cohort study. METHODS: Single-center study of 9,350 infants screened for ROP from 2009-2019. Rates of ROP and treatment-warranted ROP were evaluated in group 1 (BW < 1500g and GA ≥ 30weeks), group 2 (BW ≥ 1500g and GA < 30 weeks), and group 3 (BW ≥ 1500g and GA ≥ 30weeks)...
March 17, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36933857/three-dimensional-quantitative-description-of-the-implantable-collamer-lens-in-the-ocular-anterior-segment-of-myopic-patients-short-title-three-dimensional-description-of-implantable-collamer-lens
#15
JOURNAL ARTICLE
Tong Zhang, Fanfan Huang, Ning Gao, Miaomiao Du, Hong Cheng, Wanyao Huang, Yan Ji, Shijie Zheng, Wenjuan Wan, Ke Hu
PURPOSE: To describe the three-dimensional location of the Implantable Collamer Lens (ICL) quantitatively in the posterior ocular chamber of myopic patients. DESIGN: A cross-sectional study METHODS: : To obtain visualization models before and after mydriasis, an automatic three-dimensional (3D) imaging method based on swept-source Optical Coherence Tomography was created. Parameters like the ICL-Lens Volume (ILV), the tilt of the ICL and crystalline lens, the vault distribution index, and topographic maps were evaluated to describe the ICL location...
March 16, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36906096/preoperative-and-postoperative-clinical-factors-in-predicting-the-early-recurrence-risk-of-intermittent-exotropia-after-surgery
#16
JOURNAL ARTICLE
Zijin Wang, Tianxi Li, Xiaoxia Zuo, Lei Liu, Tong Zhang, Zhenhua Leng, Xuejuan Chen, Hu Liu
PURPOSE: Preoperative and postoperative identification of early recurrence risk factors in intermittent exotropia (IXT) patients after surgery. DESIGN: Prospective clinical cohort study. METHODS: We included 210 basic-type IXT patients who underwent either the bilateral rectus recession or unilateral recession and resection procedure and had complete follow-up until recurrence or for more than 24 months postoperatively. The primary outcome was early recurrence, defined as postoperative exodeviation over 11 prism diopters at any time beyond postoperative 1 month and within 24 months...
March 9, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36906095/efficacy-of-adjuvants-in-ophthalmic-regional-anesthesia-a-systematic-review-and-network-meta-analysis
#17
REVIEW
Jan-Philipp Bodenbender, Leopold Eberhart, Christoph Paul, Thomas Wiesmann, Florian Schubert, Ann-Kristin Schubert, Hanns-Christian Dinges
PURPOSE: This network meta-analysis aims to determine the differences between adjuvants that are used in combination with local anesthetics for ophthalmic regional anesthesia. DESIGN: Systematic review and network meta-analysis METHODS: A systematic literature search for randomized controlled trials, comparing the impact of adjuvants in ophthalmic regional anesthesia, in Embase, CENTRAL, MEDLINE and Web of Science was performed. Risk of bias was evaluated using the Cochrane risk of bias tool...
March 9, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36906094/michigan-screening-intervention-for-glaucoma-and-eye-health-through-telemedicine-program-first-year-outcomes-and-implementation-costs
#18
JOURNAL ARTICLE
Paula Anne Newman-Casey, Leslie M Niziol, Angela R Elam, Amanda K Bicket, Olivia Killeen, Denise John, Sarah Dougherty Wood, David C Musch, Jason Zhang, Leroy Johnson, Martha Kershaw, Maria A Woodward
PURPOSE: The Michigan Screening and Intervention for Glaucoma and Eye Health through Telemedicine (MI-SIGHT) program aims to engage people at high risk of glaucoma; we assess first year outcomes and costs. DESIGN: Clinical cohort study. METHODS: Participants ≥18 years were recruited from a free clinic and a federally qualified health center in Michigan. Ophthalmic technicians in the clinics collected demographic information, visual function, ocular health history, measured visual acuity, refraction, intraocular pressure, pachymetry, pupils, and took mydriatic fundus photographs and retinal nerve fiber layer optical coherence tomography...
March 9, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36906093/commercial-gene-panels-for-congenital-anterior-segment-anomalies-are-they-all-the-same
#19
JOURNAL ARTICLE
Maria Fernanda Villalba, Chris Michael Li, Parastou Pakravan, Guney Bademci, Ta Chen Peter Chang
PURPOSE: We compared next-generation sequencing multigene panels (NGS-MGP) from 5 commercial laboratories to inform the ophthalmologist's decision-making in diagnostic genetic testing for congenital anterior segment anomalies (CASA). DESIGN: Comparison of commercial genetic testing panels. METHODS: This observational study gathered publicly available information on NGS-MGP from 5 commercial laboratories for: cataracts, glaucoma, anterior segment dysgenesis (ASD), microphthalmia-anophthalmia-coloboma (MAC), corneal dystrophies, and Axenfeld-Rieger syndrome (ARS)...
March 9, 2023: American Journal of Ophthalmology
https://read.qxmd.com/read/36906092/oct-optic-nerve-head-morphology-in-myopia-ii-peri-neural-canal-scleral-bowing-and-choroidal-thickness-in-high-myopia-an-american-ophthalmological-society-thesis
#20
JOURNAL ARTICLE
Claude F Burgoyne, Ya Xing Wang, Jin Wook Jeoung, Seungwoo Hong, Stuart Gardiner, Juan Reynaud, Brad Fortune, Michaël J A Girard, Glen Sharpe, Marcelo Nicolela, Balwantray C Chauhan, Hongli Yang
PURPOSE: To use optical coherence tomography (OCT) to characterize optic nerve head (ONH) perineural canal (pNC) scleral bowing (pNC-SB) and pNC choroidal thickness (pNC-CT) in 69 highly myopic and 138 healthy, age-matched, control eyes. DESIGN: Cross-sectional, case control study. METHODS: Within ONH radial B-scans, Bruch's membrane (BM), BM opening (BMO), the anterior scleral canal opening (ASCO) and the pNC scleral surface were segmented...
March 9, 2023: American Journal of Ophthalmology
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