Dagmar Chudobova, Simona Dostalova, Iva Blazkova, Petr Michalek, Branislav Ruttkay-Nedecky, Matej Sklenar, Lukas Nejdl, Jiri Kudr, Jaromir Gumulec, Katerina Tmejova, Marie Konecna, Marketa Vaculovicova, David Hynek, Michal Masarik, Jindrich Kynicky, Rene Kizek, Vojtech Adam
There is an arising and concerning issue in the field of bacterial resistance, which is confirmed by the number of deaths associated with drug-resistant bacterial infections. The aim of this study was to compare the effects of antibiotics on Staphylococcus aureus non-resistant strain and strains resistant to cadmium or lead ions. Metal resistant strains were created by the gradual addition of 2 mM solution of metal ions (cadmium or lead) to the S. aureus culture. An increasing antimicrobial effect of ampicillin, streptomycin, penicillin and tetracycline (0, 10, 25, 50, 75, 150, 225 and 300 µM) on the resistant strains was observed using a method of growth curves...
March 2014: International Journal of Environmental Research and Public Health