Hiromu Ito, Masayo Kojima, Keiichiro Nishida, Isao Matsushita, Toshihisa Kojima, Takeo Nakayama, Hirahito Endo, Shintaro Hirata, Yuko Kaneko, Yutaka Kawahito, Mitsumasa Kishimoto, Yohei Seto, Naoyuki Kamatani, Kiichiro Tsutani, Ataru Igarashi, Mieko Hasegawa, Nobuyuki Miyasaka, Hisashi Yamanaka
OBJECTIVES: To evaluate, through a systematic review of the literature, the association between the use of biological disease-modifying antirheumatic drugs (bDMARDs) and surgical site infection (SSI) or wound healing delay after orthopedic surgery in patients with rheumatoid arthritis (RA). METHODS: A systematic review of articles indexed in the Cochrane Library, PubMed, and Web of Science from 1992 to 2012 was performed. The search aimed to identify studies describing SSI or wound healing delay in patients with RA treated with or without bDMARDs...
September 2015: Modern Rheumatology