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https://read.qxmd.com/read/26840887/ingestion-of-bioactive-collagen-hydrolysates-enhance-facial-skin-moisture-and-elasticity-and-reduce-facial-ageing-signs-in-a-randomised-double-blind-placebo-controlled-clinical-study
#1
RANDOMIZED CONTROLLED TRIAL
Naoki Inoue, Fumihito Sugihara, Xuemin Wang
BACKGROUND: Several human studies have demonstrated occurrence of two major collagen peptides, prolyl-hydroxyproline (Pro-Hyp) and hydroxyprolyl-glycine (Hyp-Gly), in human peripheral blood. Some in vitro studies have demonstrated that Pro-Hyp and Hyp-Gly exert chemotaxis on dermal fibroblasts and enhance cell proliferation. Additionally, Pro-Hyp enhances the production of hyaluronic acid by dermal fibroblasts. These findings suggest that the amounts of Pro-Hyp and Hyp-Gly in blood are important factors to show the efficacy of collagen hydrolysates on skin health...
September 2016: Journal of the Science of Food and Agriculture
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