Jean-Christoph Caubet, Odilija Rudzeviciene, Eva Gomes, Ingrid Terreehorst, Knut Brockow, Philippe A Eigenmann
Similarly to other medications, vaccines may be responsible for allergic reactions. Although IgE-mediated allergies to vaccine are extremely rare, they are clearly overdiagnosed. Indeed, accurate diagnosis of vaccine allergy is important not only to prevent serious or even life-threatening reactions, but also to avoid unnecessary vaccine restriction. Systematic approaches have been proposed and, if implemented, will likely reduce the number of children being inappropriately labeled as allergic to vaccine. In diagnosis of vaccine allergy, the patient's history is central although not sufficient...
June 2014: Pediatric Allergy and Immunology