Gerie J Glas, Ary Serpa Neto, Janneke Horn, Amalia Cochran, Barry Dixon, Elamin M Elamin, Iris Faraklas, Sharmila Dissanaike, Andrew C Miller, Marcus J Schultz
Pulmonary coagulopathy is a characteristic feature of lung injury including ventilator-induced lung injury. The aim of this individual patient data meta-analysis is to assess the effects of nebulized anticoagulants on outcome of ventilated intensive care unit (ICU) patients. A systematic search of PubMed (1966-2014), Scopus, EMBASE, and Web of Science was conducted to identify relevant publications. Studies evaluating nebulization of anticoagulants in ventilated patients were screened for inclusion, and corresponding authors of included studies were contacted to provide individual patient data...
December 2016: Annals of Intensive Care