collection
https://read.qxmd.com/read/32259905/coronary-artery-bypass-graft-surgery-versus-percutaneous-coronary-intervention-in-unprotected-left-main-coronary-artery-disease-a-systematic-review
#1
Liviu Macovei, Robert Magopet, Ana Tanasa, Cezara Raileanu, Cristina Prisacariu, Mihai Razvan Presura, Mircea Ovanez Balasanian
Critical lesion of the unprotected left main coronary disease carries a tremendous mortality burden, often associated with a diabetes status or multivessel disease, with coronary artery bypass grafting being the standard treatment for over 40 years. Percutaneous coronary intervention with drug eluting stents should be taken into consideration and could be a better option for patients with low SYNTAX score as validated by the recently published studies. This review summarizes the major randomized clinical trials and meta-analyses concerning the debate regarding percutaneous coronary intervention with drug eluting stents versus coronary artery bypass grafting for unprotected left main coronary disease, along with the latest European and American revascularization guidelines and tries to shed light on this matter...
March 30, 2020: Reviews in Cardiovascular Medicine
https://read.qxmd.com/read/31941834/long-term-outcomes-of-unprotected-left-main-coronary-artery-disease-comparison-of-coronary-artery-bypass-grafting-and-percutaneous-coronary-intervention
#2
Kai Song, Moo Hyun Kim, Jia Xin Li, Soo Jin Kim, Kwang Min Lee, Young-Rak Cho, Jong Sung Park, Tae Ho Park, Young Dae Kim, Michael S Lee
OBJECTIVE: We compared the long-term outcomes of coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for unprotected left main coronary artery (ULMCA) disease in a real-world population. BACKGROUND: CABG is the standard of care for ULMCA disease. Contemporary randomized trials have reported conflicting results with the two revascularization strategies for the treatment of ULMCA disease at intermediate-term follow-up. METHODS: We evaluated 422 consecutive patients with ULMCA disease who underwent CABG (n = 273) or PCI (n = 149) from 1998-2008...
March 2020: Journal of Invasive Cardiology
https://read.qxmd.com/read/31442489/the-eternal-debate-with-a-consistent-answer-cabg-vs-pci
#3
REVIEW
Piero Farina, Mario Fulvio Luigi Gaudino, David Paul Taggart
An ongoing debate exists over the role of percutaneous coronary intervention and coronary artery bypass grafting for revascularization in patients with multivessel or left main disease. Despite improvements in stent technology, bypass surgery still provides the best long-term results in the majority of patients. The present review focuses on randomized controlled trials and a meta-analysis published over the last 4 years.
April 2020: Seminars in Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/31301759/effect-of-age-and-sex-on-outcomes-after-stenting-or-bypass-surgery-in-left-main-coronary-artery-disease
#4
MULTICENTER STUDY
Hanbit Park, Jung-Min Ahn, Yong-Hoon Yoon, Osung Kwon, Kyusup Lee, Do-Yoon Kang, Pil Hyung Lee, Seung-Whan Lee, Seong-Wook Park, Duk-Woo Park, Seung-Jung Park
Age and sex contribute to determining coronary revascularization strategies for patients with left main coronary artery (LMCA) disease. We examined age- and sex-related differences in comparative outcomes after percutaneous coronary intervention (PCI) or coronary-artery bypass grafting (CABG) for LMCA disease. A total of 4,001 patients with LMCA disease (men, n = 3,100, women, n = 901) who underwent PCI (n = 2,615) or CABG (n = 1,386) from the Interventional Research Incorporation Society-Left MAIN Revascularization registry were analyzed...
September 1, 2019: American Journal of Cardiology
https://read.qxmd.com/read/31311660/meta-analysis-comparing-the-risk-of-myocardial-infarction-following-coronary-artery-bypass-grafting-versus-percutaneous-coronary-intervention-in-patients-with-multivessel-or-left-main-coronary-artery-disease
#5
REVIEW
Pil Hyung Lee, Hanbit Park, Ji Sung Lee, Seung-Whan Lee, Cheol Whan Lee
There is insufficient data regarding the comparative efficacy of coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) regarding myocardial infarction (MI). Our systematic review included randomized controlled trials that compared CABG versus PCI with stents in patients with multivessel or left main coronary artery disease (CAD). Included trials should have had reported event number of MI and a clinical follow-up of one or more years. Data were pooled using a random-effects model...
September 15, 2019: American Journal of Cardiology
https://read.qxmd.com/read/29502793/a-meta-analysis-comparing-percutaneous-coronary-intervention-with-drug-eluting-stents-versus-coronary-artery-bypass-grafting-in-unprotected-left-main-disease
#6
COMPARATIVE STUDY
Vamsi Kodumuri, Senthil Balasubramanian, Aviral Vij, Sisir Siddamsetti, Ankur Sethi, Rommy Khalafallah, Sandeep Khosla
Coronary artery bypass grafting (CABG) is the preferred revascularization strategy for unprotected left main disease (UPLMD). Multiple small-scale trials and registry data showed that percutaneous coronary intervention (PCI) with drug-eluting stents (DES) is a noninferior strategy with a Class IIa American College of Cardiology/American Heart Association recommendation in patients with high surgical risk and favorable anatomy. However, 2 recent large-scale randomized trials showed conflicting evidence. We conducted a meta-analysis of the existing data to compare outcomes of PCI with DES versus CABG for UPLMD...
April 15, 2018: American Journal of Cardiology
https://read.qxmd.com/read/30636684/clinical-outcomes-of-state-of-the-art-percutaneous-coronary-revascularisation-in-patients-with-three-vessel-disease-two-year-follow-up-of-the-syntax-ii-study
#7
Patrick W Serruys, Norihiro Kogame, Yuki Katagiri, Rodrigo Modolo, Pawel E Buszman, Andrés Íñiguez-Romo, Javier Goicolea, David Hildick-Smith, Andrzej Ochala, Dariusz Dudek, Jan J Piek, Joanna J Wykrzykowska, Javier Escaned, Adrian P Banning, Vasim Farooq, Yoshinobu Onuma
AIMS: The purpose of the study was to investigate whether the favourable outcomes of state-of-the-art PCI in the SYNTAX II trial, demonstrated at one year, were maintained at two-year follow-up. METHODS AND RESULTS: The SYNTAX II study was a multicentre, single-arm study that investigated the impact of a contemporary PCI strategy on clinical outcomes in 454 patients with de novo three-vessel coronary artery disease, without left main disease. Clinical outcomes in SYNTAX II were compared to the predefined PCI (SYNTAX-I PCI) and coronary artery bypass graft (SYNTAX-I CABG) cohorts from the landmark SYNTAX trial (SYNTAX-I), selected on the basis of equipoise for long-term (four-year) mortality utilising the SYNTAX score II...
June 12, 2019: EuroIntervention
https://read.qxmd.com/read/29396239/long-term-outcomes-of-new-generation-drug-eluting-stents-versus-coronary-artery-bypass-grafting-for-multivessel-and-or-left-main-coronary-artery-disease-a-bayesian-network-meta-analysis-of-randomized-controlled-trials
#8
REVIEW
George S Mina, Hussam Watti, Demiana Soliman, Anand Shewale, Jessica Atkins, Pratap Reddy, Paari Dominic
BACKGROUND: Most data guiding revascularization of multivessel disease (MVD) and/or left main disease (LMD) favor coronary artery bypass grafting (CABG) over percutaneous coronary intervention (PCI). However, those data are based on trials comparing CABG to bare metal stents (BMS) or old generation drug eluting stents (OG-DES). Hence, it is essential to outcomes of CABG to those of new generation drug eluting stents (NG-DES). METHODS: We searched PUBMED and Cochrane database for trials evaluating revascularization of MVD and/or LMD with CABG and/or PCI...
September 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/29338862/new-generation-stents-compared-with-coronary-bypass-surgery-for-unprotected-left-main-disease-a-word-of-caution
#9
Umberto Benedetto, David P Taggart, Miguel Sousa-Uva, Giuseppe Biondi-Zoccai, Antonino Di Franco, Lucas B Ohmes, Mohamed Rahouma, Mohamed Kamel, Massimo Caputo, Leonard N Girardi, Gianni D Angelini, Mario Gaudino
BACKGROUND: With the advent of bare metal stents and drug-eluting stents, percutaneous coronary intervention has emerged as an alternative to coronary artery bypass grafting surgery for unprotected left main disease. However, whether the evolution of stents technology has translated into better results after percutaneous coronary intervention remains unclear. We aimed to compare coronary artery bypass grafting with stents of different generations for left main disease by performing a Bayesian network meta-analysis of available randomized controlled trials...
May 2018: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/29102437/drug-eluting-stents-versus-coronary-artery-bypass-grafts-for-left-main-coronary-disease-a-meta-analysis-and-review-of-randomised-controlled-trials
#10
Peter Moore, Matthew Burrage, Paul Garrahy, Richard Lim, Andrew McCann, Anthony Camuglia
BACKGROUND: Revascularisation of left main coronary artery (LMCA) disease can be potentially managed with percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG). Recent randomised controlled trial (RCT) data have added to the literature on this subject and this meta-analysis aims to assess the state of the data to assist in guiding patient treatment decisions. METHODS: A systematic literature search of Cochrane Library, EMBASE, OVID, and PubMed Medline was performed...
December 2018: Heart, Lung & Circulation
https://read.qxmd.com/read/29129258/long-term-outcomes-of-bypass-grafting-versus-drug-eluting-stenting-for-left-main-coronary-artery-disease-results-from-the-iris-main-registry
#11
MULTICENTER STUDY
Pil Hyung Lee, Jong-Young Lee, Cheol Whan Lee, Seungbong Han, Jung-Min Ahn, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Seung-Jung Park
There are limited data on comparative outcomes and its determinants following coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) with drug-eluting stents (DES) for left main coronary artery disease (LMCAD) in a real-world setting. METHODS: A total of 3,504 consecutive patients with LMCAD treated with CABG (n=1,301) or PCI with DES (n=2,203) from the IRIS-MAIN registry were analyzed. The relative treatment effect of one strategy over another was assessed by propensity-score matching method...
November 2017: American Heart Journal
https://read.qxmd.com/read/29029526/percutaneous-coronary-intervention-using-drug-eluting-stents-versus-coronary-artery-bypass-graft-surgery-in-left-main-coronary-artery-disease-an-updated-meta-analysis-of-randomized-clinical-trials
#12
Lei Gao, Yuqi Liu, Zhijun Sun, Yabin Wang, Feng Cao, Yundai Chen
OBJECTIVES: To compare the safety and efficacy of percutaneous coronary intervention (PCI) using drug-eluting stent (DES) and coronary artery bypass graft (CABG) for the treatment of left main coronary artery (LMCA) disease. BACKGROUND: Several new randomized trials have recently examined the clinical outcomes of PCI and CABG in LMCA disease. However, the results of these studies were inconsistent. MATERIALS AND METHODS: We searched five online electronic databases to identify all the randomized clinical trials assessing the outcomes of PCI using DES and CABG in patients with LMCA...
September 12, 2017: Oncotarget
https://read.qxmd.com/read/29019879/percutaneous-coronary-intervention-versus-cardiac-bypass-surgery-for-left-main-coronary-artery-disease-a-trial-sequential-analysis
#13
Yicong Ye, Ming Yang, Shuyang Zhang, Yong Zeng
BACKGROUND: Several updated meta-analyses comparing percutaneous coronary intervention (PCI) with coronary artery bypass grafting (CABG) for left main coronary artery disease (LM CAD) have been published recently. However, the risk of false-positive results could be high in conventional updated meta-analyses due to repetitive testing of accumulating data. Therefore, we compared these treatment approaches via trial sequential analysis (TSA). METHODS: The MEDLINE, Embase, and Cochrane Central Register of Controlled Trials databases were searched for published randomized controlled trials (RCTs) or subgroups of RCTs comparing PCI and CABG in patients with LM CAD...
October 2017: Medicine (Baltimore)
https://read.qxmd.com/read/28958756/percutaneous-coronary-intervention-with-drug-eluting-stent-versus-coronary-artery-bypass-grafting-a-meta-analysis-of-patients-with-left-main-coronary-artery-disease
#14
COMPARATIVE STUDY
Nikolaos Spinthakis, Mohamed Farag, Diana A Gorog, Abhiram Prasad, Hamid Mahmood, Ying Gue, David Wellsted, Ashraf Nabhan, Manivannan Srinivasan
BACKGROUND: The relative efficacy and safety of percutaneous coronary intervention (PCI) with drug-eluting stents (DES), in comparison to coronary artery bypass grafting (CABG) for left main coronary artery disease (LMCAD) remains controversial. METHODS: We performed a meta-analysis of randomised studies comparing patients with LMCAD treated with PCI with DES versus those treated with CABG, with respect to clinical outcomes at 1, 3 and 5years. A secondary meta-analysis was performed according to low (<32), or high (≥33) SYNTAX score...
December 15, 2017: International Journal of Cardiology
https://read.qxmd.com/read/28799701/drug-eluting-stents-versus-coronary-artery-bypass-grafting-for-left-main-coronary-artery-disease
#15
Hisato Takagi, Tomo Ando, Takuya Umemoto
OBJECTIVES: To compare follow-up outcomes after percutaneous coronary intervention with drug-eluting stents (DES-PCI) versus coronary artery bypass grafting (CABG) for left-main coronary artery disease (LMCAD), we performed a meta-analysis of randomized controlled trials (RCTs) and observational studies with propensity-score analysis. METHODS: MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were searched through November 2016. Eligible studies were RCTs or observational studies with propensity-score analysis of DES-PCI versus CABG enrolling patients with LMCAD and reporting ≥ 6-month mortality, myocardial infarction (MI), stroke, or repeat revascularization (RRV)...
March 1, 2018: Catheterization and Cardiovascular Interventions
https://read.qxmd.com/read/28838096/revsacularization-for-unprotected-left-main-coronary-artery-disease-has-stenting-caught-up-with-bypass-surgery
#16
EDITORIAL
R Andrew Archbold
No abstract text is available yet for this article.
July 1, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://read.qxmd.com/read/28877676/long-term-outcomes-of-coronary-artery-bypass-grafting-versus-stent-pci-for-unprotected-left-main-disease-a-meta-analysis
#17
REVIEW
Salvatore De Rosa, Alberto Polimeni, Jolanda Sabatino, Ciro Indolfi
BACKGROUND: Coronary artery bypass graft (CABG) surgery has traditionally represented the standard of care for left main coronary artery (LMCA) disease. However, percutaneous coronary intervention with stent implantation (PCI) has more recently emerged as a valuable alternative. The long-time awaited results of the largest randomized trials on the long-term impact of PCI versus CABG in LMCA disease, the newly published NOBLE and EXCEL studies, revealed contrasting results. Thus, aim of the present meta-analysis was to review the most robust evidence from randomized comparisons of CABG versus PCI for revascularization of LMCA...
September 6, 2017: BMC Cardiovascular Disorders
https://read.qxmd.com/read/28886851/meta-analysis-of-comparison-of-5-year-outcomes-of-percutaneous-coronary-intervention-versus-coronary-artery-bypass-grafting-in-patients-with-unprotected-left-main-coronary-artery-in-the-era-of-drug-eluting-stents
#18
COMPARATIVE STUDY
Mahin R Khan, Waleed T Kayani, Waqas Ahmad, Ravi S Hira, Salim S Virani, Ihab Hamzeh, Hani Jneid, Nasser Lakkis, Mahboob Alam
Patients with unprotected left main coronary artery (ULMCA) disease are increasingly being treated with percutaneous coronary intervention (PCI) using drug-eluting stents (DES), but long-term outcomes comparing PCI with coronary artery bypass grafting (CABG) remain limited. We performed aggregate data meta-analyses of clinical outcomes (all-cause death, nonfatal myocardial infarction, stroke, repeat revascularization, cardiac death, and major adverse cardiac and cerebrovascular events) in studies comparing 5-year outcomes of PCI with DES versus CABG in patients with ULMCA disease...
November 1, 2017: American Journal of Cardiology
https://read.qxmd.com/read/28903139/percutaneous-coronary-intervention-vs-coronary-artery-bypass-grafting-in-patients-with-left-main-coronary-artery-stenosis-a-systematic-review-and-meta-analysis
#19
Daniele Giacoppo, Roisin Colleran, Salvatore Cassese, Antonio H Frangieh, Jens Wiebe, Michael Joner, Heribert Schunkert, Adnan Kastrati, Robert A Byrne
Importance: In patients with left main coronary artery (LMCA) stenosis, coronary artery bypass grafting (CABG) has been the standard therapy for several decades. However, some studies suggest that percutaneous coronary intervention (PCI) with drug-eluting stents may be an acceptable alternative. Objective: To compare the long-term safety of PCI with drug-eluting stent vs CABG in patients with LMCA stenosis. Data Sources: PubMed, Scopus, EMBASE, Web of Knowledge, and ScienceDirect databases were searched from December 18, 2001, to February 1, 2017...
October 1, 2017: JAMA Cardiology
https://read.qxmd.com/read/28903156/left-main-revascularization-in-2017-coronary-artery-bypass-grafting-or-percutaneous-coronary-intervention
#20
Ajay J Kirtane, Robert O Bonow
No abstract text is available yet for this article.
October 1, 2017: JAMA Cardiology
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