collection
https://read.qxmd.com/read/30199392/use-of-vasopressor-increases-the-risk-of-mortality-in-traumatic-hemorrhagic-shock-a-nationwide-cohort-study-in-japan
#1
JOURNAL ARTICLE
Makoto Aoki, Toshikazu Abe, Daizoh Saitoh, Shuichi Hagiwara, Kiyohiro Oshima
OBJECTIVES: To evaluate the possible association of vasopressor use with mortality in traumatic hemorrhagic shock patients. DESIGN: Retrospective cohort study. SETTING: Traumatic hemorrhagic shock patients at 260 emergency hospitals in Japan between 2004 and 2015. PATIENTS: Three-thousand five-hundred fifty-one traumatic hemorrhagic shock patients who had systolic hypotension (< 90 mm Hg) on arrival at the emergency department and a blood transfusion received within the first 24 hours...
December 2018: Critical Care Medicine
https://read.qxmd.com/read/28609532/effect-of-abdominal-ultrasound-on-clinical-care-outcomes-and-resource-use-among-children-with-blunt-torso-trauma-a-randomized-clinical-trial
#2
RANDOMIZED CONTROLLED TRIAL
James F Holmes, Kenneth M Kelley, Sandra L Wootton-Gorges, Garth H Utter, Lisa P Abramson, John S Rose, Daniel J Tancredi, Nathan Kuppermann
IMPORTANCE: The utility of the focused assessment with sonography for trauma (FAST) examination in children is unknown. OBJECTIVE: To determine if the FAST examination during initial evaluation of injured children improves clinical care. DESIGN, SETTING, AND PARTICIPANTS: A randomized clinical trial (April 2012-May 2015) that involved 975 hemodynamically stable children and adolescents younger than 18 years treated for blunt torso trauma at the University of California, Davis Medical Center, a level I trauma center...
June 13, 2017: JAMA
https://read.qxmd.com/read/20554319/effects-of-tranexamic-acid-on-death-vascular-occlusive-events-and-blood-transfusion-in-trauma-patients-with-significant-haemorrhage-crash-2-a-randomised-placebo-controlled-trial
#3
RANDOMIZED CONTROLLED TRIAL
Haleema Shakur, Ian Roberts, Raúl Bautista, José Caballero, Tim Coats, Yashbir Dewan, Hesham El-Sayed, Tamar Gogichaishvili, Sanjay Gupta, Jorge Herrera, Beverley Hunt, Pius Iribhogbe, Mario Izurieta, Hussein Khamis, Edward Komolafe, María-Acelia Marrero, Jorge Mejía-Mantilla, Jaime Miranda, Carlos Morales, Oluwole Olaomi, Fatos Olldashi, Pablo Perel, Richard Peto, P V Ramana, R R Ravi, Surakrant Yutthakasemsunt
BACKGROUND: Tranexamic acid can reduce bleeding in patients undergoing elective surgery. We assessed the effects of early administration of a short course of tranexamic acid on death, vascular occlusive events, and the receipt of blood transfusion in trauma patients. METHODS: This randomised controlled trial was undertaken in 274 hospitals in 40 countries. 20 211 adult trauma patients with, or at risk of, significant bleeding were randomly assigned within 8 h of injury to either tranexamic acid (loading dose 1 g over 10 min then infusion of 1 g over 8 h) or matching placebo...
July 3, 2010: Lancet
https://read.qxmd.com/read/28499514/needle-decompression-of-tension-pneumothorax-with-colorimetric-capnography
#4
JOURNAL ARTICLE
Nimesh D Naik, Matthew C Hernandez, Jeff R Anderson, Erika K Ross, Martin D Zielinski, Johnathon M Aho
BACKGROUND: The success of needle decompression for tension pneumothorax is variable, and there are no objective measures assessing effective decompression. Colorimetric capnography, which detects carbon dioxide present within the pleural space, may serve as a simple test to assess effective needle decompression. METHODS: Three swine underwent traumatically induced tension pneumothorax (standard of care, n = 15; standard of care with needle capnography, n = 15)...
November 2017: Chest
https://read.qxmd.com/read/28673640/small-tube-thoracostomy-20-22-fr-in-emergent-management-of-chest-trauma
#5
COMPARATIVE STUDY
Shinsuke Tanizaki, Shigenobu Maeda, Makoto Sera, Hideya Nagai, Minoru Hayashi, Hiroyuki Azuma, Ken-Ichi Kano, Hiroki Watanabe, Hiroshi Ishida
BACKGROUND: The optimal tube size for an emergent thoracostomy for traumatic pneumothorax or hemothorax is unknown. Both small catheter tube thoracostomy and large-bore chest tube thoracostomy have been shown to work for the nonemergent management of patients with traumatic pneumothorax or hemothorax. This study was conducted to compare the efficacy of a small chest tube with that of a large tube in emergent thoracostomy due to chest trauma. Our hypothesis was that there would be no difference in clinical outcomes including tube-related complications, the need for additional tube placement, and thoracotomy, with the replacement of large tubes with small tubes...
September 2017: Injury
https://read.qxmd.com/read/27438681/cervical-spinal-clearance-a-prospective-western-trauma-association-multi-institutional-trial
#6
MULTICENTER STUDY
Kenji Inaba, Saskya Byerly, Lisa D Bush, Matthew J Martin, David T Martin, Kimberly A Peck, Galinos Barmparas, Matthew J Bradley, Joshua P Hazelton, Raul Coimbra, Asad J Choudhry, Carlos V R Brown, Chad G Ball, Jill R Cherry-Bukowiec, Clay Cothren Burlew, Bellal Joseph, Julie Dunn, Christian T Minshall, Matthew M Carrick, Gina M Berg, Demetrios Demetriades
BACKGROUND: For blunt trauma patients who have failed the NEXUS (National Emergency X-Radiography Utilization Study) low-risk criteria, the adequacy of computed tomography (CT) as the definitive imaging modality for clearance remains controversial. The purpose of this study was to prospectively evaluate the accuracy of CT for the detection of clinically significant cervical spine (C-spine) injury. METHODS: This was a prospective multicenter observational study (September 2013 to March 2015) at 18 North American trauma centers...
December 2016: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/28274471/the-nexus-criteria-are-insufficient-to-exclude-cervical-spine-fractures-in-older-blunt-trauma-patients
#7
JOURNAL ARTICLE
Gabriel Paykin, Gerard O'Reilly, Helen M Ackland, Biswadev Mitra
BACKGROUND AND OBJECTIVE: The National Emergency X-Radiography Utilization Study (NEXUS) criteria are used to assess the need for imaging to evaluate cervical spine integrity after injury. The aim of this study was to assess the sensitivity of the NEXUS criteria in older blunt trauma patients. METHODS: Patients aged 65 years or older presenting between 1st July 2010 and 30th June 2014 and diagnosed with cervical spine fractures were identified from the institutional trauma registry...
May 2017: Injury
https://read.qxmd.com/read/28169051/how-to-measure-the-glasgow-coma-scale
#8
EDITORIAL
Steven M Green, Jason S Haukoos, David L Schriger
No abstract text is available yet for this article.
August 2017: Annals of Emergency Medicine
https://read.qxmd.com/read/23508730/summary-of-evidence-based-guideline-update-evaluation-and-management-of-concussion-in-sports-report-of-the-guideline-development-subcommittee-of-the-american-academy-of-neurology
#9
REVIEW
Christopher C Giza, Jeffrey S Kutcher, Stephen Ashwal, Jeffrey Barth, Thomas S D Getchius, Gerard A Gioia, Gary S Gronseth, Kevin Guskiewicz, Steven Mandel, Geoffrey Manley, Douglas B McKeag, David J Thurman, Ross Zafonte
OBJECTIVE: To update the 1997 American Academy of Neurology (AAN) practice parameter regarding sports concussion, focusing on 4 questions: 1) What factors increase/decrease concussion risk? 2) What diagnostic tools identify those with concussion and those at increased risk for severe/prolonged early impairments, neurologic catastrophe, or chronic neurobehavioral impairment? 3) What clinical factors identify those at increased risk for severe/prolonged early postconcussion impairments, neurologic catastrophe, recurrent concussions, or chronic neurobehavioral impairment? 4) What interventions enhance recovery, reduce recurrent concussion risk, or diminish long-term sequelae? The complete guideline on which this summary is based is available as an online data supplement to this article...
June 11, 2013: Neurology
https://read.qxmd.com/read/27774838/tranexamic-acid-in-patients-undergoing-coronary-artery-surgery
#10
RANDOMIZED CONTROLLED TRIAL
Paul S Myles, Julian A Smith, Andrew Forbes, Brendan Silbert, Mohandas Jayarajah, Thomas Painter, D James Cooper, Silvana Marasco, John McNeil, Jean S Bussières, Shay McGuinness, Kelly Byrne, Matthew T V Chan, Giovanni Landoni, Sophie Wallace
BACKGROUND: Tranexamic acid reduces the risk of bleeding among patients undergoing cardiac surgery, but it is unclear whether this leads to improved outcomes. Furthermore, there are concerns that tranexamic acid may have prothrombotic and proconvulsant effects. METHODS: In a trial with a 2-by-2 factorial design, we randomly assigned patients who were scheduled to undergo coronary-artery surgery and were at risk for perioperative complications to receive aspirin or placebo and tranexamic acid or placebo...
January 12, 2017: New England Journal of Medicine
https://read.qxmd.com/read/27773351/introduction-of-a-pan-scan-protocol-for-blunt-trauma-activations-what-are-the-consequences
#11
JOURNAL ARTICLE
Melissa K James, Sebastian D Schubl, Michael P Francois, Geoffrey K Doughlin, Shi-Wen Lee
STUDY OBJECTIVE: The aim of this study is to determine if the introduction of a pan-scan protocol during the initial assessment for blunt trauma activations would affect missed injuries, incidental findings, treatment times, radiation exposure, and cost. METHODS: A 6-month prospective study was performed on patients with blunt trauma at a level 1 trauma center. During the last 3 months of the study, a pan-scan protocol was introduced to the trauma assessment. Categorical data were analyzed by Fisher exact test and continuous data were analyzed by Mann-Whitney nonparametric test...
January 2017: American Journal of Emergency Medicine
https://read.qxmd.com/read/22395870/spinal-cord-injury-resulting-from-injury-missed-on-ct-scan-the-danger-of-relying-on-ct-alone-for-collar-removal
#12
JOURNAL ARTICLE
Gregory Gebauer, Meredith Osterman, James Harrop, Alexander Vaccaro
BACKGROUND: Strict criteria have been used before removing cervical collars in patients with injuries who have midline pain or are unable to be reliably examined. This sometimes leads to prolonged immobilization in cervical collars or use of MRI to rule out injury. Several studies suggest a collar may be removed in the absence of fractures, dislocation, or pathologic subluxation on a cervical CT scan. This may avoid the morbidity of prolonged cervical immobilization or cost of advanced imaging study but risks devastating consequences from missing injuries...
June 2012: Clinical Orthopaedics and related Research
https://read.qxmd.com/read/26720428/goal-directed-hemostatic-resuscitation-of-trauma-induced-coagulopathy-a-pragmatic-randomized-clinical-trial-comparing-a-viscoelastic-assay-to-conventional-coagulation-assays
#13
RANDOMIZED CONTROLLED TRIAL
Eduardo Gonzalez, Ernest E Moore, Hunter B Moore, Michael P Chapman, Theresa L Chin, Arsen Ghasabyan, Max V Wohlauer, Carlton C Barnett, Denis D Bensard, Walter L Biffl, Clay C Burlew, Jeffrey L Johnson, Fredric M Pieracci, Gregory J Jurkovich, Anirban Banerjee, Christopher C Silliman, Angela Sauaia
BACKGROUND: Massive transfusion protocols (MTPs) have become standard of care in the management of bleeding injured patients, yet strategies to guide them vary widely. We conducted a pragmatic, randomized clinical trial (RCT) to test the hypothesis that an MTP goal directed by the viscoelastic assay thrombelastography (TEG) improves survival compared with an MTP guided by conventional coagulation assays (CCA). METHODS: This RCT enrolled injured patients from an academic level-1 trauma center meeting criteria for MTP activation...
June 2016: Annals of Surgery
https://read.qxmd.com/read/27543523/fluid-resuscitation-management-in-patients-with-burns-update
#14
REVIEW
P Guilabert, G Usúa, N Martín, L Abarca, J P Barret, M J Colomina
Since 1968, when Baxter and Shires developed the Parkland formula, little progress has been made in the field of fluid therapy for burn resuscitation, despite advances in haemodynamic monitoring, establishment of the 'goal-directed therapy' concept, and the development of new colloid and crystalloid solutions. Burn patients receive a larger amount of fluids in the first hours than any other trauma patients. Initial resuscitation is based on crystalloids because of the increased capillary permeability occurring during the first 24 h...
September 2016: British Journal of Anaesthesia
https://read.qxmd.com/read/27473552/computed-tomography-use-for-adults-with-head-injury-describing-likely-avoidable-emergency-department-imaging-based-on-the-canadian-ct-head-rule
#15
JOURNAL ARTICLE
Adam L Sharp, Ganesh Nagaraj, Ellen J Rippberger, Ernest Shen, Clifford J Swap, Matthew A Silver, Taylor McCormick, David R Vinson, Jerome R Hoffman
BACKGROUND: Millions of head computed tomography (CT) scans are ordered annually, but the extent of avoidable imaging is poorly defined. OBJECTIVES: The objective was to determine the prevalence of likely avoidable CT imaging among adults evaluated for head injury in 14 community emergency departments (EDs) in Southern California. METHODS: We conducted an electronic health record (EHR) database and chart review of adult ED trauma encounters receiving a head CT from 2008 to 2013...
January 2017: Academic Emergency Medicine
https://read.qxmd.com/read/26895089/use-of-cpr-in-hemorrhagic-shock-a-dog-model
#16
JOURNAL ARTICLE
David R Jeffcoach, Juan J Gallegos, Sophy A Jesty, Patricia N Coan, Jason Chen, Robert Eric Heidel, Brian J Daley
INTRODUCTION: Cardiopulmonary resuscitation was designed for sudden cardiac events usually triggered by thrombotic phenomena. Despite this, it is routinely used in trauma resuscitations as per the American Heart guidelines. There is no data supporting the use of chest compressions in hemorrhagic shock. An evidence-based cardiopulmonary resuscitation (CPR) protocol has been developed for dogs. We sought to determine the effects and outcomes of chest compressions in hemorrhagic shock in a canine model...
July 2016: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/27371186/total-body-ct-for-initial-diagnosis-of-severe-trauma
#17
COMMENT
Thomas Erik Wurmb, Michael Bernhard
No abstract text is available yet for this article.
August 13, 2016: Lancet
https://read.qxmd.com/read/27371185/immediate-total-body-ct-scanning-versus-conventional-imaging-and-selective-ct-scanning-in-patients-with-severe-trauma-react-2-a-randomised-controlled-trial
#18
RANDOMIZED CONTROLLED TRIAL
Joanne C Sierink, Kaij Treskes, Michael J R Edwards, Benn J A Beuker, Dennis den Hartog, Joachim Hohmann, Marcel G W Dijkgraaf, Jan S K Luitse, Ludo F M Beenen, Markus W Hollmann, J Carel Goslings
BACKGROUND: Published work suggests a survival benefit for patients with trauma who undergo total-body CT scanning during the initial trauma assessment; however, level 1 evidence is absent. We aimed to assess the effect of total-body CT scanning compared with the standard work-up on in-hospital mortality in patients with trauma. METHODS: We undertook an international, multicentre, randomised controlled trial at four hospitals in the Netherlands and one in Switzerland...
August 13, 2016: Lancet
https://read.qxmd.com/read/27015578/intraoperative-hypotensive-resuscitation-for-patients-undergoing-laparotomy-or-thoracotomy-for-trauma-early-termination-of-a-randomized-prospective-clinical-trial
#19
RANDOMIZED CONTROLLED TRIAL
Matthew M Carrick, Catherine Anne Morrison, Nicole M Tapia, Jan Leonard, James W Suliburk, Michael A Norman, Francis J Welsh, Bradford G Scott, Kathy R Liscum, Sally R Raty, Matthew J Wall, Kenneth L Mattox
BACKGROUND: Hemorrhagic shock is responsible for one third of trauma related deaths. We hypothesized that intraoperative hypotensive resuscitation would improve survival for patients undergoing operative control of hemorrhage following penetrating trauma. METHODS: Between July 1, 2007, and March 28, 2013, penetrating trauma patients aged 14 years to 45 years with a systolic blood pressure of 90 mm Hg or lower requiring laparotomy or thoracotomy for control of hemorrhage were randomized 1:1 based on a target minimum mean arterial pressure (MAP) of 50 mm Hg (experimental arm, LMAP) or 65 mm Hg (control arm, HMAP)...
June 2016: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/22626015/immediate-and-delayed-traumatic-intracranial-hemorrhage-in-patients-with-head-trauma-and-preinjury-warfarin-or-clopidogrel-use
#20
MULTICENTER STUDY
Daniel K Nishijima, Steven R Offerman, Dustin W Ballard, David R Vinson, Uli K Chettipally, Adina S Rauchwerger, Mary E Reed, James F Holmes
STUDY OBJECTIVE: Patients receiving warfarin or clopidogrel are considered at increased risk for traumatic intracranial hemorrhage after blunt head trauma. The prevalence of immediate traumatic intracranial hemorrhage and the cumulative incidence of delayed traumatic intracranial hemorrhage in these patients, however, are unknown. The objective of this study is to address these gaps in knowledge. METHODS: A prospective, observational study at 2 trauma centers and 4 community hospitals enrolled emergency department (ED) patients with blunt head trauma and preinjury warfarin or clopidogrel use from April 2009 through January 2011...
June 2012: Annals of Emergency Medicine
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