Raphael Twerenbold, Juan Pablo Costabel, Thomas Nestelberger, Roberto Campos, Desiree Wussler, Rosina Arbucci, Marcia Cortes, Jasper Boeddinghaus, Benjamin Baumgartner, Christian H Nickel, Roland Bingisser, Patrick Badertscher, Christian Puelacher, Jeanne du Fay de Lavallaz, Karin Wildi, Maria Rubini Giménez, Joan Walter, Mario Meier, Benjamin Hafner, Pedro Lopez Ayala, Jens Lohrmann, Valentina Troester, Luca Koechlin, Tobias Zimmermann, Danielle M Gualandro, Tobias Reichlin, Florencia Lambardi, Silvana Resi, Alberto Alves de Lima, Marcelo Trivi, Christian Mueller
BACKGROUND: The European Society of Cardiology (ESC) recommends the 0/1-h algorithm for rapid triage of patients with suspected non-ST-segment elevation myocardial infarction (MI). However, its impact on patient management and safety when routinely applied is unknown. OBJECTIVES: This study sought to determine these important real-world outcome data. METHODS: In a prospective international study enrolling patients presenting with acute chest discomfort to the emergency department (ED), the authors assessed the real-world performance of the ESC 0/1-h algorithm using high-sensitivity cardiac troponin T embedded in routine clinical care and its associated 30-day rates of major adverse cardiac events (MACE) (the composite of cardiovascular death and MI)...
July 30, 2019: Journal of the American College of Cardiology