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Shuofei Yang, Xinxin Fan, Weiwei Ding, Baochen Liu, Jiaxiang Meng, Kai Wang, Xingjiang Wu, Jieshou Li
No early serum marker of disease severity contributes to the treatment decision-making process of acute superior mesenteric venous thrombosis (ASMVT). This study aims to assess the value of serum D-dimer level in the first 3 days after admission as a severity marker of ASMVT patients. From May 2010 to June 2014, 50 consecutive patients of ASMVT were enrolled in this observational study. The serum D-dimer level was measured on a daily basis during the first 3 days after admission as well as other laboratory-testing parameters, clinical score, and outcome variables recorded during the same period...
December 2014: Medicine (Baltimore)
N Komen, R W F de Bruin, G J Kleinrensink, J Jeekel, J F Lange
BACKGROUND: Colorectal anastomotic leakage (AL) is a severe complication leading to severe infection, sepsis and sometimes death. At present the diagnosis is made clinically, usually at 6-8 days after surgery. An objective biomarker reflecting the intra-abdominal milieu surrounding the anastomosis would be a useful additional diagnostic tool to make the diagnosis of AL before its clinical presentation. This review aims to assess the current status of the search for such a biomarker in peritoneal fluid...
February 2008: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
José Raimundo Araujo de Azevedo, Orlando Jorge Martins Torres, Nicolau Gregori Czeczko, Felipe Francisco Tuon, Paulo Afonso Nunes Nassif, Gleim Dias de Souza
OBJECTIVE: To evaluate the tendency of the plasma concentration and clearance of procalcitonin (PCT-c) as biomarkers of prognosis of patients with severe sepsis and septic shock, compared to another early prognosis marker, the number of SIRS criteria at sepsis diagnosis. METHODS: We conducted a prospective, observational, cohort study, with patients with severe sepsis and septic shock. The serum procalcitonin was determined at diagnosis of sepsis and after 24 and 48 hours...
December 2012: Revista do Colégio Brasileiro de Cirurgiões
Richard R Watkins, Tracy L Lemonovich
The biomarker procalcitonin (PCT) has been used to diagnose and monitor a number of clinically significant infections. Serum levels of PCT are often increased in the presence of bacterial and fungal infections but not viral infections or noninfectious inflammation. Intra-abdominal infections (IAIs) are serious conditions that pose difficult challenges to physicians and the healthcare system. Researchers have evaluated PCT in the management of IAIs, both for diagnosis and for guiding antibiotic therapy. The studies have produced mixed results, leading to controversy on the utility of PCT in IAIs...
February 2012: Expert Review of Anti-infective Therapy
F Le Roux, A Lipsker, S Mesureur, E Haraux
No abstract text is available yet for this article.
April 2016: Journal of Visceral Surgery
Hasan H Eker, G H van Ramshorst, B de Goede, H W Tilanus, H J Metselaar, R A de Man, J F Lange, G Kazemier
BACKGROUND: Patients with both cirrhosis and ascites have a 20% risk of developing umbilical hernia. A retrospective study from our center comparing conservative management of umbilical hernia with elective repair in these patients showed a significant risk of mortality as a result of hernia incarceration in conservatively treated patients. The goal of this study was to assess the safety and efficacy of elective umbilical hernia repair in these patients prospectively. METHODS: Patients with liver cirrhosis and ascites presenting with an umbilical hernia were included in this study...
September 2011: Surgery
Steven M Strasberg, Michael J Pucci, L Michael Brunt, Daniel J Deziel
Less than complete cholecystectomy has been advocated for difficult operative conditions for more than 100 years. These operations are called partial or subtotal cholecystectomy, but the terms are poorly defined and do not stipulate whether a remnant gallbladder is created. This article briefly reviews the history and development of the procedures and introduces new terms to clarify the field. The term partial is discarded, and subtotal cholecystectomies are divided into "fenestrating" and "reconstituting" types...
January 2016: Journal of the American College of Surgeons
Federico Coccolini, Walter Biffl, Fausto Catena, Marco Ceresoli, Osvaldo Chiara, Stefania Cimbanassi, Luca Fattori, Ari Leppaniemi, Roberto Manfredi, Giulia Montori, Giovanni Pesenti, Michael Sugrue, Luca Ansaloni
The indications for Open Abdomen (OA) are generally all those situations in which is ongoing the development an intra-abdominal hypertension condition (IAH), in order to prevent the development of abdominal compartmental syndrome (ACS). In fact all those involved in care of a critically ill patient should in the first instance think how to prevent IAH and ACS. In case of ACS goal directed therapy to achieve early opening and early closure is the key: paradigm of closure shifts to combination of therapies including negative pressure wound therapy and dynamic closure, in order to reduce complications and avoid incisional hernia...
2015: World Journal of Emergency Surgery: WJES
F E Muysoms, S A Antoniou, K Bury, G Campanelli, J Conze, D Cuccurullo, A C de Beaux, E B Deerenberg, B East, R H Fortelny, J-F Gillion, N A Henriksen, L Israelsson, A Jairam, A Jänes, J Jeekel, M López-Cano, M Miserez, S Morales-Conde, D L Sanders, M P Simons, M Śmietański, L Venclauskas, F Berrevoet
BACKGROUND: The material and the surgical technique used to close an abdominal wall incision are important determinants of the risk of developing an incisional hernia. Optimising closure of abdominal wall incisions holds a potential to prevent patients suffering from incisional hernias and for important costs savings in health care. METHODS: The European Hernia Society formed a Guidelines Development Group to provide guidelines for all surgical specialists who perform abdominal incisions in adult patients on the materials and methods used to close the abdominal wall...
February 2015: Hernia: the Journal of Hernias and Abdominal Wall Surgery
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