Katrina J Allen, Jennifer J Koplin, Anne-Louise Ponsonby, Lyle C Gurrin, Melissa Wake, Peter Vuillermin, Pamela Martin, Melanie Matheson, Adrian Lowe, Marnie Robinson, Dean Tey, Nicholas J Osborne, Thanh Dang, Hern-Tze Tina Tan, Leone Thiele, Deborah Anderson, Helen Czech, Jeeva Sanjeevan, Giovanni Zurzolo, Terence Dwyer, Mimi L K Tang, David Hill, Shyamali C Dharmage
BACKGROUND: Epidemiological evidence has shown that pediatric food allergy is more prevalent in regions further from the equator, suggesting that vitamin D insufficiency may play a role in this disease. OBJECTIVE: To investigate the role of vitamin D status in infantile food allergy. METHODS: A population sample of 5276 one-year-old infants underwent skin prick testing to peanut, egg, sesame, and cow's milk or shrimp. All those with a detectable wheal and a random sample of participants with negative skin prick test results attended a hospital-based food challenge clinic...
April 2013: Journal of Allergy and Clinical Immunology