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https://read.qxmd.com/read/26141556/peritoneal-carcinomatosis-a-malignant-disease-with-an-embryological-origin
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Augusto Pereira, Elsa Mendizabal, Juan de Leon, Tirso Pérez-Medina, Javier F Magrina, Paul M Magtibay, Ana Rodríguez-Tapia, Santiago Lizarraga, Luís Ortiz-Quintana
INTRODUCTION: In 1931, Simpson et al. coined the term "peritoneal carcinomatosis" to describe the regional spread of ovarian tumors as localized or extended with involvement of the peritoneal serous membrane and neighboring anatomical structures. Research into the origin of peritoneal carcinomatosis is based on two phases in a woman's life: EMBRYO DEVELOPMENT: During week 3, the bilaminar disc becomes a trilaminar disc called the mesoderm. Inside the lateral plate mesoderm, the coelomic cavity is divided into 2 layers: the parietal (somatic) mesoderm, which gives rise to the parietal peritoneum and pleural surfaces; and the visceral (splanchnic) mesoderm, which gives rise to the visceral peritoneum, visceral surface of the pleura, gonadal stroma, and the muscular layer of the hollow viscera and its mesenteries...
September 2015: Surgical Oncology
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