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By Isabel Acosta-Ochoa Nephrology senior staff. Valladolid. Spain
Joanne Silberner
No abstract text is available yet for this article.
March 18, 2019: BMJ: British Medical Journal
Jan Stepanek, Rebecca S Blue, Scott Parazynski
New England Journal of Medicine, Volume 380, Issue 11, Page 1053-1060, March 2019.
March 14, 2019: New England Journal of Medicine
Aaron P Davis, Helen Chadburn, Justin Moat, Robert O'Sullivan, Serene Hargreaves, Eimear Nic Lughadha
Wild coffee species are critical for coffee crop development and, thus, for sustainability of global coffee production. Despite this fact, the extinction risk and conservation priority status of the world's coffee species are poorly known. Applying IUCN Red List of Threatened Species criteria to all (124) wild coffee species, we undertook a gap analysis for germplasm collections and protected areas and devised a crop wild relative (CWR) priority system. We found that at least 60% of all coffee species are threatened with extinction, 45% are not held in any germplasm collection, and 28% are not known to occur in any protected area...
January 2019: Science Advances
Abi Rimmer
No abstract text is available yet for this article.
February 21, 2019: BMJ: British Medical Journal
Reidar P Lystad, Benjamin T Brown
BACKGROUND: Game of Thrones is a popular television series known for its violent and graphic portrayal of the deaths of its characters. This study aimed to examine the mortality and survival of important characters in Game of Thrones. METHODS: Important characters appearing in Seasons 1 to 7 of Game of Thrones were included, and data on sociodemographic factors, time to death, and circumstances of death were recorded. Kaplan-Meier survival analysis with Cox proportional hazard regression modelling were used to quantify survival times and probabilities and to identify independent predictors of mortality, respectively...
December 10, 2018: Injury Epidemiology
Pierre Ronco, Brad Rovin
No abstract text is available yet for this article.
March 2019: Kidney International
David R King
New England Journal of Medicine, Volume 380, Issue 8, Page 763-770, February 2019.
February 21, 2019: New England Journal of Medicine
M Righini, H Robert-Ebadi, G Le Gal
The diagnosis of pulmonary embolism (PE) is nowadays based on the sequential use of several diagnostic tests rather than on a single test. These diagnostic strategies are safe and have been prospectively validated. The first step after identifying patients with suspicion of PE is to establish the pre-test clinical probability. Several scores are available in order to make a standardised and reproducible assessment of the clinical probability, and therefore represent precious diagnostic tools. Indeed, clinical probability guides further investigations...
February 8, 2019: La Revue de Médecine Interne
Peter A Brennan, Rachel Oeppen, John Knighton, Mike Davidson
No abstract text is available yet for this article.
February 6, 2019: BMJ: British Medical Journal
Jean-Rodolphe Mackanga, Nalia Dibambou, Emeline-Gracia Mouendou Mouloungui, Josaphat Iba-Ba, Ulrich Davy Kombila, Patrice-Emery Itoudi Bignoumba, Inès-Flore Maganga Moussavou, Landry Missounga, Jean-Baptiste Moussavou Kombila, Jean-Bruno Boguikouma
BACKGROUND: Acquired hyponatremia is a life threatening event. Intravenous infusion of a mixture of 5% glucose and sodium solute is mainly used, but its contribution in the occurrence of acquired hyponatremia in adult, is under-investigated outside intensive care unit. OBJECTIVE: To evaluate the place of intravenous infusion of a mixture of 5% glucose and sodium in predicting acquired hyponatremia in adult polyvalent medicine service. PATIENTS AND METHODS: A case-control study have been conducted...
February 1, 2019: Néphrologie & Thérapeutique
David K Kim, Paul Hunter
No abstract text is available yet for this article.
February 5, 2019: Annals of Internal Medicine
Muhammad Asim, Mohamad M Alkadi, Hania Asim, Adil Ghaffar
Dehydration and volume depletion describe two distinct body fluid deficit disorders with differing pathophysiology, clinical manifestations and treatment approaches. However, the two are often confused or equated with each other. Here, we address a number of commonly encountered misconceptions about body-fluid deficit disorders, analyse their origins and propose approaches to overcome them.
January 21, 2019: World Journal of Nephrology
Katherine Walker, Michael Ben-Meir, William Dunlop, Rachel Rosler, Adam West, Gabrielle O'Connor, Thomas Chan, Diana Badcock, Mark Putland, Kim Hansen, Carmel Crock, Danny Liew, David Taylor, Margaret Staples
OBJECTIVES: To evaluate the changes in productivity when scribes were used by emergency physicians in emergency departments in Australia and assess the effect of scribes on throughput. DESIGN: Randomised, multicentre clinical trial. SETTING: Five emergency departments in Victoria used Australian trained scribes during their respective trial periods. Sites were broadly representative of Australian emergency departments: public (urban, tertiary, regional referral, paediatric) and private, not for profit...
January 30, 2019: BMJ: British Medical Journal
Mohamed A Osman, Mona Alrukhaimi, Gloria E Ashuntantang, Ezequiel Bellorin-Font, Mohammed Benghanem Gharbi, Branko Braam, Mark Courtney, John Feehally, David C Harris, Vivekanand Jha, Kailash Jindal, David W Johnson, Kamyar Kalantar-Zadeh, Rumeyza Kazancioglu, Scott Klarenbach, Adeera Levin, Meaghan Lunney, Ikechi G Okpechi, Timothy Olusegun Olanrewaju, Jeffrey Perl, Harun Ur Rashid, Eric Rondeau, Babatunde Lawal Salako, Arian Samimi, Laura Sola, Irma Tchokhonelidze, Natasha Wiebe, Chih-Wei Yang, Feng Ye, Alexander Zemchenkov, Ming-Hui Zhao, Aminu K Bello
The health workforce is the cornerstone of any health care system. An adequately trained and sufficiently staffed workforce is essential to reach universal health coverage. In particular, a nephrology workforce is critical to meet the growing worldwide burden of kidney disease. Despite some attempts, the global nephrology workforce and training capacity remains widely unknown. This multinational cross-sectional survey was part of the Global Kidney Health Atlas project, a new initiative administered by the International Society of Nephrology (ISN)...
February 2018: Kidney International Supplements
Adrienne G Waks, Eric P Winer
Importance: Breast cancer will be diagnosed in 12% of women in the United States over the course of their lifetimes and more than 250 000 new cases of breast cancer were diagnosed in the United States in 2017. This review focuses on current approaches and evolving strategies for local and systemic therapy of breast cancer. Observations: Breast cancer is categorized into 3 major subtypes based on the presence or absence of molecular markers for estrogen or progesterone receptors and human epidermal growth factor 2 (ERBB2; formerly HER2): hormone receptor positive/ERBB2 negative (70% of patients), ERBB2 positive (15%-20%), and triple-negative (tumors lacking all 3 standard molecular markers; 15%)...
January 22, 2019: JAMA: the Journal of the American Medical Association
Rebecca Coombes
No abstract text is available yet for this article.
January 16, 2019: BMJ: British Medical Journal
Andrew McGuigan, Paul Kelly, Richard C Turkington, Claire Jones, Helen G Coleman, R Stephen McCain
This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further research in this understudied malignancy. Pancreatic adenocarcinoma is a lethal condition with a rising incidence, predicted to become the second leading cause of cancer death in some regions. It often presents at an advanced stage, which contributes to poor five-year survival rates of 2%-9%, ranking firmly last amongst all cancer sites in terms of prognostic outcomes for patients...
November 21, 2018: World Journal of Gastroenterology: WJG
Erica S Shenoy, Eric Macy, Theresa Rowe, Kimberly G Blumenthal
Importance: β-Lactam antibiotics are among the safest and most effective antibiotics. Many patients report allergies to these drugs that limit their use, resulting in the use of broad-spectrum antibiotics that increase the risk for antimicrobial resistance and adverse events. Observations: Approximately 10% of the US population has reported allergies to the β-lactam agent penicillin, with higher rates reported by older and hospitalized patients. Although many patients report that they are allergic to penicillin, clinically significant IgE-mediated or T lymphocyte-mediated penicillin hypersensitivity is uncommon (<5%)...
January 15, 2019: JAMA: the Journal of the American Medical Association
Alexandra Witze
No abstract text is available yet for this article.
January 2019: Nature
Sophie De Seigneux, Belen Ponte, Karine Hadaya, Patrick Saudan
Major advances in the treatment of ANCA associated-renal vasculitides, IGA nephropathy and renal autosomal dominant polycystic disease were published within the past year. There is neither clear benefit of early initiation of renal replacement therapy in the intensive care unit nor with the use of chloride-poor solutions to prevent kidney failure. Maintenance parenteral iron supplementation in hemodialysis patients is neither associated with infectious nor cardiovascular risks. Cognitive decline may be more associated with hemodialysis than peritoneal dialysis...
January 9, 2019: Revue Médicale Suisse
2019-01-12 14:57:13
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