Abinaya Ramakrishnan, Cynthia Zheng, Manuel L Fontes, Frederic W Lombard, Austin A Woolard, Yaping Shi, Matthew S Shotwell, Frederic T Billings, Mias Pretorius, Jonathan P Wanderer, Rushikesh Vyas, Tarek S Absi, Ashish S Shah, Miklos D Kertai
PURPOSE: Increased mean platelet volume (MPV) may indicate platelet activation, platelet aggregation, and a resulting prothrombotic state. Such changes in the postoperative period have been associated with organ injury and adverse outcomes. We hypothesized that changes in MPV after cardiac surgery are associated with both a higher risk of acute kidney injury (AKI) and mortality. METHODS: In this retrospective study, we evaluated consecutive patients undergoing adult cardiac surgery patients between 12 December 2011 and 5 June 2018...
September 15, 2020: Canadian Journal of Anaesthesia