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Cocaine induced lung injury

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2 papers 0 to 25 followers
By Jason Mann No BS pulmonary critical care fellow
Carlos S Restrepo, Jorge A Carrillo, Santiago Martínez, Paulina Ojeda, Aura L Rivera, Ami Hatta
Cocaine is the illicit drug whose abuse most often results in cardiopulmonary symptoms and emergency treatment. Habitual smoking of alkaloidal cocaine ("freebase," "crack") has replaced nasal insufflation as the most common method of abuse. Smoking of cocaine exposes the lung directly to the volatilized drug as well as to the other combustion products of the smoked mixture, thereby increasing the risk of adverse pulmonary effects. A wide variety of pulmonary complications including interstitial pneumonitis, fibrosis, pulmonary hypertension, alveolar hemorrhage, asthma exacerbation, barotrauma, thermal airway injury, hilar lymphadenopathies, and bullous emphysema may be associated with the inhalation of crack cocaine or of associated substances such as talc, silica, and lactose...
July 2007: Radiographics: a Review Publication of the Radiological Society of North America, Inc
Renata Rocha de Almeida, Luciana Soares de Souza, Alexandre Dias Mançano, Arthur Soares Souza, Klaus Loureiro Irion, Luiz Felipe Nobre, Gláucia Zanetti, Bruno Hochhegger, Jorge Luiz Pereira e Silva, Edson Marchiori
Cocaine is the most commonly used illicit drug among patients presenting at hospital emergency departments and the most frequent cause of drug-related deaths reported by medical examiners. Various respiratory problems temporally associated with cocaine use have been reported. Acute and chronic uses also are responsible for lung complications, such as pulmonary edema, alveolar hemorrhage, pulmonary hypertension, organizing pneumonia, emphysema, barotrauma, infection, cancer, eosinophilic disease, and aspiration pneumonia...
April 2014: Lung
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