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X Wu, L-H Hang, Y-F Chen, H Wang, D-H Shao, Z Chen
BACKGROUND: It is unclear whether the sedative, analgesic or sympatholytic effects of adjunctive dexmedetomidine contribute to reduced analgesic requirements in general anesthesia. This study aimed to assess the analgesic effect of dexmedetomidine on intraoperative opioid requirements using body movement as observation indicator at similar BIS-guided sedative depth in propofol anesthesia. METHODS: Ninety patients were randomly divided into three groups to receive administration of saline, and dexmedetomidine at 0...
December 2015: Irish Journal of Medical Science
Ting Pang, Fei Li, San-qing Jin, Bo Li, Li-hong Chen, Xin-yang Li, Dong-xue Li, Yi Wen, Hai Jiang, Jing-ling Tian
OBJECTIVE: To evaluate the effect of titrated target-controlled infusion with propofol and remifentanil on anesthetics consumption and anesthesia depth in patients undergoing elective laparoscopic colorectal surgery. METHODS: Sixty ASA I-III patients for elective laparoscopic colorectal surgery were enrolled. Titrated target-controlled infusion (TCI) with propofol and remifentanil was performed. Plasma concentration of the drugs was administered by titrated method to maintain bispectral index (BIS) in the range of 40-60 with systolic blood pressure (SBP) fluctuation within 20% of the basic value...
June 2013: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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