collection
https://read.qxmd.com/read/26017091/associations-between-serotonin-transporter-gene-slc6a4-methylation-and-clinical-characteristics-and-cortical-thickness-in-children-with-adhd
#21
JOURNAL ARTICLE
S Park, J-M Lee, J-W Kim, D-Y Cho, H J Yun, D H Han, J H Cheong, B-N Kim
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a common, highly heritable psychiatric disorder. Additionally, environmental factors such as perinatal stress and early adversities contribute to the occurrence and severity of ADHD. Recently, DNA methylation has emerged as a mechanism that potentially mediates gene-environmental interaction effects in the aetiology and phenomenology of psychiatric disorders. Here, we investigated whether serotonin transporter gene (SLC6A4) methylation patterns were associated with clinical characteristics and regional cortical thickness in children with ADHD...
October 2015: Psychological Medicine
https://read.qxmd.com/read/25989041/ncam1-ttc12-ankk1-drd2-gene-cluster-and-the-clinical-and-genetic-heterogeneity-of-adults-with-adhd
#22
JOURNAL ARTICLE
Nina R Mota, Diego L Rovaris, Djenifer B Kappel, Felipe A Picon, Eduardo S Vitola, Carlos A I Salgado, Rafael G Karam, Luis A Rohde, Eugenio H Grevet, Claiton H D Bau
Dysfunctions of the dopaminergic system have been implicated on the etiology of Attention Deficit/Hyperactivity Disorder (ADHD). Meta-analyses addressing the association of the dopamine receptor D2 (DRD2) gene and ADHD were inconclusive due to excessive heterogeneity across studies. Both the great phenotypic heterogeneity of ADHD and the complexity of the genomic region where DRD2 is located could contribute to the inconsistent findings. Most previous DRD2 studies focused on the well-known Taq1A (rs1800497) SNP, which is actually placed in a neighbor gene (ANKK1)...
September 2015: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://read.qxmd.com/read/22474711/encouraging-news-about-adhd-drugs-and-heart-risk-in-adults
#23
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March 2012: Harvard Mental Health Letter
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