Reiko Nishihara, Kana Wu, Paul Lochhead, Teppei Morikawa, Xiaoyun Liao, Zhi Rong Qian, Kentaro Inamura, Sun A Kim, Aya Kuchiba, Mai Yamauchi, Yu Imamura, Walter C Willett, Bernard A Rosner, Charles S Fuchs, Edward Giovannucci, Shuji Ogino, Andrew T Chan
BACKGROUND: Colonoscopy and sigmoidoscopy provide protection against colorectal cancer, but the magnitude and duration of protection, particularly against cancer of the proximal colon, remain uncertain. METHODS: We examined the association of the use of lower endoscopy (updated biennially from 1988 through 2008) with colorectal-cancer incidence (through June 2010) and colorectal-cancer mortality (through June 2012) among participants in the Nurses' Health Study and the Health Professionals Follow-up Study...
September 19, 2013: New England Journal of Medicine