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RANDOMIZED CONTROLLED TRIAL
Sanjit S Jolly, John A Cairns, Salim Yusuf, Brandi Meeks, Janice Pogue, Michael J Rokoss, Sasko Kedev, Lehana Thabane, Goran Stankovic, Raul Moreno, Anthony Gershlick, Saqib Chowdhary, Shahar Lavi, Kari Niemelä, Philippe Gabriel Steg, Ivo Bernat, Yawei Xu, Warren J Cantor, Christopher B Overgaard, Christoph K Naber, Asim N Cheema, Robert C Welsh, Olivier F Bertrand, Alvaro Avezum, Ravinay Bhindi, Samir Pancholy, Sunil V Rao, Madhu K Natarajan, Jurriën M ten Berg, Olga Shestakovska, Peggy Gao, Petr Widimsky, Vladimír Džavík
BACKGROUND: During primary percutaneous coronary intervention (PCI), manual thrombectomy may reduce distal embolization and thus improve microvascular perfusion. Small trials have suggested that thrombectomy improves surrogate and clinical outcomes, but a larger trial has reported conflicting results. METHODS: We randomly assigned 10,732 patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary PCI to a strategy of routine upfront manual thrombectomy versus PCI alone...
April 9, 2015: New England Journal of Medicine
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