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Man Huang, Dejun Wang, Zhijun Xu, Yongshan Xu, Xiaoping Xu, Yuefeng Ma, Zheng Xia
PURPOSE: Large-scale genome-wide association studies have identified TREM2 variants to be significantly associated with Alzheimer's disease (AD) in caucasian population. The goal of this systematic study and meta-analysis was to assess the association between Triggering receptor expressed on myeloid cells 2 (TREM2) variants and AD in East Asian population. METHODS: In this study, literatures were searched in PubMed, MEDLINE, EMBASE, and the Cochrane library to screen citations from January 1990 to June 2014...
September 2015: American Journal of Alzheimer's Disease and Other Dementias
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